General information for g11364.t6
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Ribosomal protein S6 kinase beta.
Parent gene
- The parent gene g11364 is located on chr_1: 15812752..15813654 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11364 | g11364.t6 | isoform | g11364.t6 | 15812177 | 15813654 |
| chr_1 | g11364 | g11364.t6 | exon | g11364.t6.exon1 | 15812177 | 15812305 |
| chr_1 | g11364 | g11364.t6 | cds | g11364.t6.CDS1 | 15812178 | 15812305 |
| chr_1 | g11364 | g11364.t6 | exon | g11364.t6.exon2 | 15812358 | 15812422 |
| chr_1 | g11364 | g11364.t6 | cds | g11364.t6.CDS2 | 15812358 | 15812422 |
| chr_1 | g11364 | g11364.t6 | exon | g11364.t6.exon3 | 15812488 | 15812542 |
| chr_1 | g11364 | g11364.t6 | cds | g11364.t6.CDS3 | 15812488 | 15812542 |
| chr_1 | g11364 | g11364.t6 | exon | g11364.t6.exon4 | 15812600 | 15812678 |
| chr_1 | g11364 | g11364.t6 | cds | g11364.t6.CDS4 | 15812600 | 15812678 |
| chr_1 | g11364 | g11364.t6 | exon | g11364.t6.exon5 | 15812744 | 15812999 |
| chr_1 | g11364 | g11364.t6 | cds | g11364.t6.CDS5 | 15812744 | 15812999 |
| chr_1 | g11364 | g11364.t6 | exon | g11364.t6.exon6 | 15813065 | 15813105 |
| chr_1 | g11364 | g11364.t6 | cds | g11364.t6.CDS6 | 15813065 | 15813105 |
| chr_1 | g11364 | g11364.t6 | exon | g11364.t6.exon7 | 15813565 | 15813654 |
| chr_1 | g11364 | g11364.t6 | cds | g11364.t6.CDS7 | 15813565 | 15813654 |
| chr_1 | g11364 | g11364.t6 | TSS | g11364.t6 | 15813931 | 15813931 |
| chr_1 | g11364 | g11364.t6 | TTS | g11364.t6 | NA | NA |
Sequences
>g11364.t6 Gene=g11364 Length=715
ATGGCCGATGTATTTCAATTTGAGATCGATGAAACGCATCAGGAGGCGAATATTGATGCA
GACGATAATGATGAAGTTATTATAGATGATATGGATCTGGAAACGGAATTAAATATGAAT
AAAAATATGGACCTTGAAACTGAAACGATACAATTAAGCGAAGAAATCGTAAACCCGCCA
GGAAGAAAATTGGGACCGCAAGATTTTGAACTCAAAAAAGTGCTAGGAAAGGGAGGGTAC
GGAAAGGTATTTCAAGTGAAAAAAGTTACAGGTAAAGACGCAGGTAACTTTTTTGCAATG
AAGGTACTCAAAAAAGCATCTATTGTTCGAAATCAAAAAGACACAGCTCATACAAGAGCC
GAAAGAAATATATTGGAAGCTGTAAAACATCCATTTATTGTAGAATTAGTTTATGCATTT
CAAACTGGTGGAAAGTTATATTTGATTTTAGAATATCTCAGTGGAGGTGAACTTTTTATG
CATTTAGAACGTGAAGGAATATTTTTAGAGGACACTACATGCTTTTATTTGAATGAGATA
GTACTAGCATTAGAACATCTTCATTCGCTAGGAATCATTTATAGAGACCTTAAACCAGAA
AATGTCTTACTTGATGCACAAGGACATGTAAAATTAACGGATTTTGGACTTTGCAAAGAA
CATATTCATGAGGGCATAACTGCTTGGACGTTTTGTGGAACAATTGAATATATGT
>g11364.t6 Gene=g11364 Length=238
MADVFQFEIDETHQEANIDADDNDEVIIDDMDLETELNMNKNMDLETETIQLSEEIVNPP
GRKLGPQDFELKKVLGKGGYGKVFQVKKVTGKDAGNFFAMKVLKKASIVRNQKDTAHTRA
ERNILEAVKHPFIVELVYAFQTGGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLNEI
VLALEHLHSLGIIYRDLKPENVLLDAQGHVKLTDFGLCKEHIHEGITAWTFCGTIEYM
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g11364.t6 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 69 | 156 | 5.7E-77 |
| 9 | g11364.t6 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 157 | 238 | 5.7E-77 |
| 2 | g11364.t6 | PANTHER | PTHR24351:SF171 | RIBOSOMAL PROTEIN S6 KINASE BETA-2 | 8 | 238 | 2.4E-106 |
| 3 | g11364.t6 | PANTHER | PTHR24351 | RIBOSOMAL PROTEIN S6 KINASE | 8 | 238 | 2.4E-106 |
| 1 | g11364.t6 | Pfam | PF00069 | Protein kinase domain | 69 | 238 | 2.1E-46 |
| 7 | g11364.t6 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 75 | 101 | - |
| 6 | g11364.t6 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 192 | 204 | - |
| 10 | g11364.t6 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 69 | 238 | 36.951 |
| 5 | g11364.t6 | SMART | SM00220 | serkin_6 | 69 | 238 | 4.6E-25 |
| 4 | g11364.t6 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 62 | 238 | 5.26E-56 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
