General information for g11394.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Brain-specific angiogenesis inhibitor 1-associated protein 2.
Parent gene
- The parent gene g11394 is located on chr_1: 15942591..15944329 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11394 | g11394.t1 | isoform | g11394.t1 | 15940698 | 15944329 |
| chr_1 | g11394 | g11394.t1 | exon | g11394.t1.exon1 | 15940698 | 15941349 |
| chr_1 | g11394 | g11394.t1 | cds | g11394.t1.CDS1 | 15940698 | 15941349 |
| chr_1 | g11394 | g11394.t1 | exon | g11394.t1.exon2 | 15941453 | 15941604 |
| chr_1 | g11394 | g11394.t1 | cds | g11394.t1.CDS2 | 15941453 | 15941604 |
| chr_1 | g11394 | g11394.t1 | exon | g11394.t1.exon3 | 15941670 | 15941823 |
| chr_1 | g11394 | g11394.t1 | cds | g11394.t1.CDS3 | 15941670 | 15941823 |
| chr_1 | g11394 | g11394.t1 | exon | g11394.t1.exon4 | 15941890 | 15941968 |
| chr_1 | g11394 | g11394.t1 | cds | g11394.t1.CDS4 | 15941890 | 15941968 |
| chr_1 | g11394 | g11394.t1 | exon | g11394.t1.exon5 | 15942044 | 15942513 |
| chr_1 | g11394 | g11394.t1 | cds | g11394.t1.CDS5 | 15942044 | 15942513 |
| chr_1 | g11394 | g11394.t1 | exon | g11394.t1.exon6 | 15942590 | 15942929 |
| chr_1 | g11394 | g11394.t1 | cds | g11394.t1.CDS6 | 15942590 | 15942929 |
| chr_1 | g11394 | g11394.t1 | exon | g11394.t1.exon7 | 15943789 | 15943951 |
| chr_1 | g11394 | g11394.t1 | cds | g11394.t1.CDS7 | 15943789 | 15943951 |
| chr_1 | g11394 | g11394.t1 | exon | g11394.t1.exon8 | 15944285 | 15944329 |
| chr_1 | g11394 | g11394.t1 | cds | g11394.t1.CDS8 | 15944285 | 15944329 |
| chr_1 | g11394 | g11394.t1 | TSS | g11394.t1 | 15944776 | 15944776 |
| chr_1 | g11394 | g11394.t1 | TTS | g11394.t1 | NA | NA |
Sequences
>g11394.t1 Gene=g11394 Length=2055
ATGGATGAAGAAAAGAATGTCAAAGCTATTGATGCAATTTATAAGAACATCCTTGAAAGA
TTTAACCCTGAATCGAAGAAAATGCTTATGAATGCCAAAACATATCTGAAAGCTCTACAA
AATTCATCACAAGCATCAAAATTATTTAGTGAATCTCTCACAAAACTTGCAGAAAACGCT
CAATCGGCTCCGGGAGCCAAAGATATCGGTTCCGCACTAGCCAAAATAATTGATGTATTT
AAGTCAATTGAAGAGCAACATCAGCAAATTCTCAAAGTAATTTATGTCGATTTTATCTGT
CCTCTTGAGACAAATTTGGCGAAAGATGTCAAAGTTATTCAAGCAGAGCAGAAAAAATTT
TCTCATCAGTTAAAAATGCGAACTGATAGTTTTGATAAAGCAACAGCGGCTGTTAAGAAA
CATAGAAAGAAGAAAAATAATGCAGAACGAGAATTAAAATGTATTCAAATGCTCGAGGAA
GAAAAGAAAAATCTTGACAATTTTATGCAGCGAGAAAGTAACAATGCGCTCTTACAAGAG
CGACGTCGATATGGCTTTATTTTGGAACGATATACGGAAAGCATAGCAAAGCATTATCTA
CATTTTTTTAATAATAGCTTCGAAAGTATAAATAGCAACATTCAACGTTGGAATGAGATT
GCTGCAACACGTGAAATGATCACTACTTCACCAATGAGTGCTGAAGGCACGTTATCGAGA
AAAAACAATGGCGAGACGCTGACAATAAAGAAAGACAATGAAAATTTCAATTCCAGAAGA
AATTTGGAACGAGTGAGTCTAAGCTTAAGCGATGAAAGTGAATCGAATTTGTCAATTAAC
AACAACAACAAAAATGATTCAGAAAATAGTCGTCCGCCTCATTATTCGATGGACAAAATA
GCTTCAAATCCTAACAATCGAATTGTAGTGGCCGTCTATGGTTATACAGCGACACAAGAA
AATCAATTGAGCTTCGCTGAGGGAGATAAAATATGTTTAATTGGCGATAATATAAGTGGC
TGGCGATTTGGAGAAAATGTCAAGACGAAAACTTTCGGATGGTTCCCAAGCTCATACGTC
AATGGAAATCATCCAAAAACTAATGGAAATACAAAAGAAAATGATATAATGAATGAAGGA
ACATTTGGAAATACGTTGGGCAGTAGATATTCAATCAGTAAACAGAGAAATTTTCAAAAT
CCACCAGCTGTTAGAGCACCATCTCCACCAGCGTCTCAAAACAACGAAATGAATGCAAAA
CAGAGTTTACGCGGAATTTATAGCAGCAACGACAGTGGATTCGATAATGAAGTTCCACCC
ATTGCTCCAGAAATAGATTATTCAGATGACGATGATAATGATGATGATGATAATGAGCAT
ATGCCGCAAAAAGTTCCAATAAGAAAACCAAATGATGGTTTCTTAAGTAGTGGACAATCT
AATAGTCATGGCGATTTAACAGAGAATATTTCGACTATGAAACGCAATAAAGGATTTTGG
AGGTTTAGTAGATCAGAAGATTTACTTGAAGGTATGGGTTTATGGAAACATCGAGATCTT
TTACCAATTGAAAATATTGATGATAGCACTTTAAAGAAATCATCAGTCAATTATAAAAAG
CCAGTTGAAAAGAATACGATTAACTCAGAGATAATTCATCAAAGAATGTCAAAGGAAAAG
CCTCATGAGGAAGGTTTCGATGATATTTATGATGAGACACCAAAAAGACGAAATCATACT
GGTCCGGTAATTATGAATGAAAATAGTTTCTATAAAGAATTGCAGGATACAAATTTCTAT
GATGACGATGATGATGATGTTCTTGTGCGAACGGTCAAGAGAAAAGAAATTTTAAAACAA
TATCATTCAAGTGAAACAGATACGGAACTCTCGATAAACTCGGATCCATATGATTGCGTT
TTACAAAAAACAAATAATAATACTCTGTTACCACGAACAAAACTTTTAAAAGCTAGAAAT
GAATCTTATGATCACGGTTTAGAAAGCTCTTCAAATAAGACTAAAGCTAAAAGTTTTCAA
TCATGGCACCATTAA
>g11394.t1 Gene=g11394 Length=684
MDEEKNVKAIDAIYKNILERFNPESKKMLMNAKTYLKALQNSSQASKLFSESLTKLAENA
QSAPGAKDIGSALAKIIDVFKSIEEQHQQILKVIYVDFICPLETNLAKDVKVIQAEQKKF
SHQLKMRTDSFDKATAAVKKHRKKKNNAERELKCIQMLEEEKKNLDNFMQRESNNALLQE
RRRYGFILERYTESIAKHYLHFFNNSFESINSNIQRWNEIAATREMITTSPMSAEGTLSR
KNNGETLTIKKDNENFNSRRNLERVSLSLSDESESNLSINNNNKNDSENSRPPHYSMDKI
ASNPNNRIVVAVYGYTATQENQLSFAEGDKICLIGDNISGWRFGENVKTKTFGWFPSSYV
NGNHPKTNGNTKENDIMNEGTFGNTLGSRYSISKQRNFQNPPAVRAPSPPASQNNEMNAK
QSLRGIYSSNDSGFDNEVPPIAPEIDYSDDDDNDDDDNEHMPQKVPIRKPNDGFLSSGQS
NSHGDLTENISTMKRNKGFWRFSRSEDLLEGMGLWKHRDLLPIENIDDSTLKKSSVNYKK
PVEKNTINSEIIHQRMSKEKPHEEGFDDIYDETPKRRNHTGPVIMNENSFYKELQDTNFY
DDDDDDVLVRTVKRKEILKQYHSSETDTELSINSDPYDCVLQKTNNNTLLPRTKLLKARN
ESYDHGLESSSNKTKAKSFQSWHH
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g11394.t1 | Coils | Coil | Coil | 131 | 175 | - |
| 8 | g11394.t1 | Gene3D | G3DSA:1.20.1270.60 | Arfaptin | 1 | 220 | 9.5E-58 |
| 7 | g11394.t1 | Gene3D | G3DSA:2.30.30.40 | SH3 Domains | 303 | 362 | 1.1E-14 |
| 15 | g11394.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 231 | 255 | - |
| 11 | g11394.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 267 | 290 | - |
| 16 | g11394.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 267 | 292 | - |
| 12 | g11394.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 464 | 488 | - |
| 14 | g11394.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 473 | 488 | - |
| 13 | g11394.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 663 | 684 | - |
| 3 | g11394.t1 | PANTHER | PTHR14206:SF7 | INSULIN RECEPTOR SUBSTRATE 53 KDA, ISOFORM A | 1 | 478 | 1.3E-92 |
| 4 | g11394.t1 | PANTHER | PTHR14206 | BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 | 1 | 478 | 1.3E-92 |
| 1 | g11394.t1 | Pfam | PF08397 | IRSp53/MIM homology domain | 14 | 222 | 1.5E-27 |
| 2 | g11394.t1 | Pfam | PF00018 | SH3 domain | 310 | 357 | 1.5E-11 |
| 18 | g11394.t1 | ProSiteProfiles | PS51338 | IMD domain profile. | 1 | 190 | 26.348 |
| 17 | g11394.t1 | ProSiteProfiles | PS50002 | Src homology 3 (SH3) domain profile. | 304 | 365 | 21.277 |
| 10 | g11394.t1 | SMART | SM00326 | SH3_2 | 307 | 364 | 2.0E-14 |
| 5 | g11394.t1 | SUPERFAMILY | SSF103657 | BAR/IMD domain-like | 2 | 226 | 1.01E-48 |
| 6 | g11394.t1 | SUPERFAMILY | SSF50044 | SH3-domain | 285 | 361 | 1.44E-16 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
| GO:0007009 | plasma membrane organization | BP |
KEGG
Orthology
- This transcript has been annotated with K05627 (BAI1-associated protein 2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
