General information for g11405.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Hepatic leukemia factor.
Parent gene
- The parent gene g11405 is located on chr_1: 16009328..16018020 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11405 | g11405.t1 | TTS | g11405.t1 | 16008070 | 16008070 |
| chr_1 | g11405 | g11405.t1 | isoform | g11405.t1 | 16008195 | 16011776 |
| chr_1 | g11405 | g11405.t1 | exon | g11405.t1.exon1 | 16008195 | 16008281 |
| chr_1 | g11405 | g11405.t1 | cds | g11405.t1.CDS1 | 16008195 | 16008281 |
| chr_1 | g11405 | g11405.t1 | exon | g11405.t1.exon2 | 16008346 | 16008599 |
| chr_1 | g11405 | g11405.t1 | cds | g11405.t1.CDS2 | 16008346 | 16008599 |
| chr_1 | g11405 | g11405.t1 | exon | g11405.t1.exon3 | 16008802 | 16009060 |
| chr_1 | g11405 | g11405.t1 | cds | g11405.t1.CDS3 | 16008802 | 16009060 |
| chr_1 | g11405 | g11405.t1 | exon | g11405.t1.exon4 | 16009328 | 16009473 |
| chr_1 | g11405 | g11405.t1 | cds | g11405.t1.CDS4 | 16009328 | 16009473 |
| chr_1 | g11405 | g11405.t1 | exon | g11405.t1.exon5 | 16011335 | 16011776 |
| chr_1 | g11405 | g11405.t1 | cds | g11405.t1.CDS5 | 16011335 | 16011776 |
| chr_1 | g11405 | g11405.t1 | TSS | g11405.t1 | 16012647 | 16012647 |
Sequences
>g11405.t1 Gene=g11405 Length=1188
ATGGAATATCAGCAATTGCCGCCTGTTTCAATGATAATCGGAACACCGAATCAATCTCAA
TCACAAGCATCCCATTTACATAACTTGACAAACAGCAATAATAATAACAATAATGGATCA
AATAATCAACAGTTGCTTACAATGCAACCACCATTACTTCCACTACAAGTTGCTCACAAT
CTTCATCAGCTTACATCGCAGAATGGCAATTCACATGGTCTCGGCAATGCCACACAAAAT
CAAAACACTCAATCACTACCACCAACCACCCAGCTCTTGCAAGCAATTCACAACAATACT
CAGCAGCATCCAAATATGAATGGAAATGGCAATAATAACACAGGCAATAATACTAGTGAC
AATAACGCACCCAACGATGAGAATAATCGTTGGACACAATATCAAGTGCAACAATTATGG
CGACATCATGCATATTTGAACGGAAAAACAAGTAATAAAGACATTTGCGGTGACGATAAA
CATAAAGAAGATGGTGATCCCTGGAATGTGGAAGCACAAGCAGCATTTTTAGGACCGAAC
CTGTGGGATAAAACATTACCATACGACACAAATCTAAAAGTACATCAATACGCTGATTTG
GATGAATTTTTATCGGAAAATGGTATACCAGTCGATGGCTTAAATGGCTTACCGAGCAGT
CATTTGGGACATTCAGCGAGTATGGGTAATGGAAGCGGTGGCGGAGGTGGTGGTGTAACA
AATAATCGCAACGATTTGGGCCTCTCACTAGGACTAAGTGCAGTTACAAAGCGAGAAAGA
TCTCCTTCACCATCTGATTGTATGAGTCCCGATACTATAAACAATCCACCTTCTCCTGCA
GACTCCATTTTCGATGTTACAGCATTTTCAATGTCTTCTTCACGCGATTTTGATCCACGT
ACGCGTGCATTCTCGGATGAAGATTTAAAACCGCAACCAATGATAAAAAAGTCTCGCAAG
CAATTCGTACCCGATGAAATGAAAGATGACAAATACTGGGCGCGCAGACGAAAGAACAAC
ATGGCCGCCAAGCGCTCGCGGGATGCTCGCCGCATGAAAGAAAATCAAATAGCGCTTCGA
GCCGGATATTTAGAAAAAGAAAACATGAATTTGCACCGTGAAGTTGAGCAGCTAAAACAA
GAAAATATGGAGCTAAGAGCGCGTTTATCAAAATATCAAGAAGTGTAA
>g11405.t1 Gene=g11405 Length=395
MEYQQLPPVSMIIGTPNQSQSQASHLHNLTNSNNNNNNGSNNQQLLTMQPPLLPLQVAHN
LHQLTSQNGNSHGLGNATQNQNTQSLPPTTQLLQAIHNNTQQHPNMNGNGNNNTGNNTSD
NNAPNDENNRWTQYQVQQLWRHHAYLNGKTSNKDICGDDKHKEDGDPWNVEAQAAFLGPN
LWDKTLPYDTNLKVHQYADLDEFLSENGIPVDGLNGLPSSHLGHSASMGNGSGGGGGGVT
NNRNDLGLSLGLSAVTKRERSPSPSDCMSPDTINNPPSPADSIFDVTAFSMSSSRDFDPR
TRAFSDEDLKPQPMIKKSRKQFVPDEMKDDKYWARRRKNNMAAKRSRDARRMKENQIALR
AGYLEKENMNLHREVEQLKQENMELRARLSKYQEV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g11405.t1 | CDD | cd14695 | bZIP_HLF | 328 | 387 | 3.01894E-32 |
| 6 | g11405.t1 | Coils | Coil | Coil | 361 | 395 | - |
| 5 | g11405.t1 | Gene3D | G3DSA:1.20.5.170 | - | 316 | 393 | 1.3E-18 |
| 2 | g11405.t1 | PANTHER | PTHR11988 | THYROTROPH EMBRYONIC FACTOR RELATED | 136 | 395 | 1.7E-88 |
| 3 | g11405.t1 | PANTHER | PTHR11988:SF27 | GH27708P | 136 | 395 | 1.7E-88 |
| 1 | g11405.t1 | Pfam | PF07716 | Basic region leucine zipper | 328 | 381 | 5.9E-17 |
| 9 | g11405.t1 | ProSiteProfiles | PS50217 | Basic-leucine zipper (bZIP) domain profile. | 329 | 392 | 11.668 |
| 8 | g11405.t1 | SMART | SM00338 | brlzneu | 327 | 391 | 7.1E-8 |
| 4 | g11405.t1 | SUPERFAMILY | SSF57959 | Leucine zipper domain | 328 | 389 | 1.13E-16 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006357 | regulation of transcription by RNA polymerase II | BP |
| GO:0006355 | regulation of transcription, DNA-templated | BP |
| GO:0003700 | DNA-binding transcription factor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K09057 (hepatic leukemia factor)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
