General information for g11421.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Calcium/calmodulin-dependent protein kinase type 1.
Parent gene
- The parent gene g11421 is located on chr_1: 16137611..16142196 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11421 | g11421.t1 | TSS | g11421.t1 | 16134278 | 16134278 |
| chr_1 | g11421 | g11421.t1 | isoform | g11421.t1 | 16134924 | 16139144 |
| chr_1 | g11421 | g11421.t1 | exon | g11421.t1.exon1 | 16134924 | 16135042 |
| chr_1 | g11421 | g11421.t1 | cds | g11421.t1.CDS1 | 16134924 | 16135042 |
| chr_1 | g11421 | g11421.t1 | exon | g11421.t1.exon2 | 16135656 | 16135790 |
| chr_1 | g11421 | g11421.t1 | cds | g11421.t1.CDS2 | 16135656 | 16135790 |
| chr_1 | g11421 | g11421.t1 | exon | g11421.t1.exon3 | 16136553 | 16136609 |
| chr_1 | g11421 | g11421.t1 | cds | g11421.t1.CDS3 | 16136553 | 16136609 |
| chr_1 | g11421 | g11421.t1 | exon | g11421.t1.exon4 | 16137087 | 16137161 |
| chr_1 | g11421 | g11421.t1 | cds | g11421.t1.CDS4 | 16137087 | 16137161 |
| chr_1 | g11421 | g11421.t1 | exon | g11421.t1.exon5 | 16137611 | 16137749 |
| chr_1 | g11421 | g11421.t1 | cds | g11421.t1.CDS5 | 16137611 | 16137749 |
| chr_1 | g11421 | g11421.t1 | exon | g11421.t1.exon6 | 16137813 | 16137891 |
| chr_1 | g11421 | g11421.t1 | cds | g11421.t1.CDS6 | 16137813 | 16137891 |
| chr_1 | g11421 | g11421.t1 | exon | g11421.t1.exon7 | 16137954 | 16137985 |
| chr_1 | g11421 | g11421.t1 | cds | g11421.t1.CDS7 | 16137954 | 16137985 |
| chr_1 | g11421 | g11421.t1 | exon | g11421.t1.exon8 | 16138045 | 16138082 |
| chr_1 | g11421 | g11421.t1 | cds | g11421.t1.CDS8 | 16138045 | 16138082 |
| chr_1 | g11421 | g11421.t1 | exon | g11421.t1.exon9 | 16138146 | 16138190 |
| chr_1 | g11421 | g11421.t1 | cds | g11421.t1.CDS9 | 16138146 | 16138190 |
| chr_1 | g11421 | g11421.t1 | exon | g11421.t1.exon10 | 16138565 | 16138635 |
| chr_1 | g11421 | g11421.t1 | cds | g11421.t1.CDS10 | 16138565 | 16138635 |
| chr_1 | g11421 | g11421.t1 | exon | g11421.t1.exon11 | 16138694 | 16138820 |
| chr_1 | g11421 | g11421.t1 | cds | g11421.t1.CDS11 | 16138694 | 16138820 |
| chr_1 | g11421 | g11421.t1 | exon | g11421.t1.exon12 | 16138886 | 16138973 |
| chr_1 | g11421 | g11421.t1 | cds | g11421.t1.CDS12 | 16138886 | 16138973 |
| chr_1 | g11421 | g11421.t1 | exon | g11421.t1.exon13 | 16139043 | 16139144 |
| chr_1 | g11421 | g11421.t1 | cds | g11421.t1.CDS13 | 16139043 | 16139144 |
| chr_1 | g11421 | g11421.t1 | TTS | g11421.t1 | NA | NA |
Sequences
>g11421.t1 Gene=g11421 Length=1107
ATGCCCCTGTTTGGTAAAAAAGACTCTAAAAAGAATTCGAGGAAGGATATCAACAAGGAT
ATTGACAAACAAATAGCTAATATTGAAGATAAATACCATTTAAGACAAGTTTTAGGAAAT
GGTGCCTTTTCGGAAGTTCGACTTGGTGAAAGCAAAGAAAACCCGGGTCAATTATTTGCC
ATCAAAATTATTGATAAAAAAGCACTTAAAGGAAAGGAGGACTCACTGGAAAATGAAATT
AAAGTACTTAGAAGGTTCTCCGCAATGAATGCAAATGATAATGATAATGATAATAATATT
GAAACTAAGCGGTTAACTCATCCGAACATAGTGCAACTGCTAGAAACATACGAGGATAAG
ACAAAAGTTTATTTAGTTATGGAACTGGTAACTGGTGGTGAACTTTTCGATAGAATTGTA
GAAAAAGGTTCATATACAGAGAAAGATGCATCAGGTCTCATTCGACAAGTGCTTGAAGCT
GTCGATTATATGCATGAACAGGGAGTCGTTCATCGAGATCTAAAACCTGAAAATTTACTC
TATTACAACACCGAAGAAGATAGTAAAATAATGATAAGTGATTTTGGTCTCTCAAAGATG
GAAGATTCTGGAATAATGGCAACAGCATGTGGCACACCTGGTTATGTGGCGCCTGAAGTT
TTAGCCCAAAAACCATATGGCAAAGCAGTTGATGTCTGGTCAATAGGTGTTATATCATAC
ATTCTCTTATGTGGATATCCACCATTCTATGACGAAAATGATGCAAATCTTTTTGCACAA
ATTTTAAAAGGCGATTTCGAATTTGATTCACCATATTGGGATGAAATTAGTGAATCTGCA
AAAGACTTCATTCAGCACTTAATGTGTGTAGATGTTGAAAAGAGATATACGTGTAAACAA
GCACTTGCACATCCTTGGATTTCCGGAAATGCAGCCAGTAGTAAAAATATTCACGGCACT
GTATCAGAGCAATTGAAGAAGAATTTTGCAAAATCTCGTTGGAAGCAAGCATATCATGCA
GCTACGGTTATCAGACAAATGCAACGAATGGCATTGAATAGTGGTGGATCGAGTCGAAAC
AATGCTCGTAATGAATCTGAAAAGTAA
>g11421.t1 Gene=g11421 Length=368
MPLFGKKDSKKNSRKDINKDIDKQIANIEDKYHLRQVLGNGAFSEVRLGESKENPGQLFA
IKIIDKKALKGKEDSLENEIKVLRRFSAMNANDNDNDNNIETKRLTHPNIVQLLETYEDK
TKVYLVMELVTGGELFDRIVEKGSYTEKDASGLIRQVLEAVDYMHEQGVVHRDLKPENLL
YYNTEEDSKIMISDFGLSKMEDSGIMATACGTPGYVAPEVLAQKPYGKAVDVWSIGVISY
ILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKDFIQHLMCVDVEKRYTCKQ
ALAHPWISGNAASSKNIHGTVSEQLKKNFAKSRWKQAYHAATVIRQMQRMALNSGGSSRN
NARNESEK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g11421.t1 | CDD | cd14083 | STKc_CaMKI | 28 | 306 | 0.0 |
| 7 | g11421.t1 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 14 | 129 | 1.6E-30 |
| 8 | g11421.t1 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 130 | 346 | 5.2E-73 |
| 3 | g11421.t1 | PANTHER | PTHR24347:SF116 | CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1G | 20 | 87 | 6.3E-154 |
| 5 | g11421.t1 | PANTHER | PTHR24347 | SERINE/THREONINE-PROTEIN KINASE | 20 | 87 | 6.3E-154 |
| 2 | g11421.t1 | PANTHER | PTHR24347:SF116 | CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1G | 91 | 359 | 6.3E-154 |
| 4 | g11421.t1 | PANTHER | PTHR24347 | SERINE/THREONINE-PROTEIN KINASE | 91 | 359 | 6.3E-154 |
| 1 | g11421.t1 | Pfam | PF00069 | Protein kinase domain | 103 | 307 | 1.3E-66 |
| 11 | g11421.t1 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 38 | 62 | - |
| 10 | g11421.t1 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 169 | 181 | - |
| 13 | g11421.t1 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 32 | 307 | 50.237 |
| 12 | g11421.t1 | SMART | SM00220 | serkin_6 | 32 | 307 | 9.9E-103 |
| 6 | g11421.t1 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 23 | 328 | 4.45E-86 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
- This transcript has been annotated with K08794 (calcium/calmodulin-dependent protein kinase I)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
