General information for g11445.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Collagen alpha-1(XVIII) chain.
Parent gene
- The parent gene g11445 is located on chr_1: 16305287..16305802 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11445 | g11445.t1 | TTS | g11445.t1 | 16300976 | 16300976 |
| chr_1 | g11445 | g11445.t1 | isoform | g11445.t1 | 16301514 | 16305802 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon1 | 16301514 | 16301650 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS1 | 16301514 | 16301650 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon2 | 16301716 | 16301787 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS2 | 16301716 | 16301787 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon3 | 16301869 | 16301927 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS3 | 16301869 | 16301927 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon4 | 16301993 | 16302181 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS4 | 16301993 | 16302181 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon5 | 16302243 | 16302373 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS5 | 16302243 | 16302373 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon6 | 16302432 | 16302473 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS6 | 16302432 | 16302473 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon7 | 16302530 | 16302661 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS7 | 16302530 | 16302661 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon8 | 16302729 | 16302821 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS8 | 16302729 | 16302821 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon9 | 16302875 | 16302948 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS9 | 16302875 | 16302948 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon10 | 16303009 | 16303038 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS10 | 16303009 | 16303038 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon11 | 16303096 | 16303129 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS11 | 16303096 | 16303129 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon12 | 16303223 | 16303309 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS12 | 16303223 | 16303309 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon13 | 16303377 | 16303453 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS13 | 16303377 | 16303453 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon14 | 16303596 | 16303623 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS14 | 16303596 | 16303623 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon15 | 16303702 | 16303727 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS15 | 16303702 | 16303727 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon16 | 16303783 | 16303840 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS16 | 16303783 | 16303840 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon17 | 16304018 | 16304053 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS17 | 16304018 | 16304053 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon18 | 16304241 | 16304263 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS18 | 16304241 | 16304263 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon19 | 16304324 | 16304432 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS19 | 16304324 | 16304432 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon20 | 16304509 | 16304583 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS20 | 16304509 | 16304583 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon21 | 16304680 | 16304756 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS21 | 16304680 | 16304756 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon22 | 16304823 | 16304833 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS22 | 16304823 | 16304833 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon23 | 16304995 | 16305034 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS23 | 16304995 | 16305034 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon24 | 16305114 | 16305143 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS24 | 16305114 | 16305143 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon25 | 16305210 | 16305288 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS25 | 16305210 | 16305288 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon26 | 16305584 | 16305727 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS26 | 16305584 | 16305727 |
| chr_1 | g11445 | g11445.t1 | exon | g11445.t1.exon27 | 16305794 | 16305802 |
| chr_1 | g11445 | g11445.t1 | cds | g11445.t1.CDS27 | 16305794 | 16305802 |
| chr_1 | g11445 | g11445.t1 | TSS | g11445.t1 | 16306518 | 16306518 |
Sequences
>g11445.t1 Gene=g11445 Length=1902
ATGGCTATGGTTATATCAAGTAGAGCAAAAGGGATGATTGGCGCATTTATATCATTGATA
CTTTTATCAACTGTTCTTGTAACTGCATCGACAAAAGGCTGGTGGTTTGGTTTAAATAAA
AATAATGGTGAACATGTTGCTGCTCGAATACAGGCAAACAGTGACTCAGATTTTAATGAT
TATAGTAACGAAAATGAAAGTCCAGTTTTACAGGCTCCACCAGATTTTAAGAATTATGGT
GGATACAGAAAGGGTGAAAAAGGTGAGAAGGGAGCTAGAGGAATTCCAGGCGATTCAATC
AGAGGGCCACCTGGACCTCCAGGTCCAAAAGGAGAATGTCAAATAGTTAATTTTAATAAT
AATACCAACAGTTACAATAATAATTTCAAACAGACGGAACAAAAATTAGCACCAGTTTGT
GCATGTAATTACGACAATATTATTGATATTCTTCACAATGAATCGGTAATTCAAATTCTA
CGAGGCCCTCAAGGCCCTCCGGGATTAACGGGAGCTCCCGGTCAAAAAGGGGAAATGGGC
GAAAGAGGAGCAGATGGTATTGATGGAATTCCAGGATTGCCAGGGACACCAGGAGAGAGT
TCATCTAATTGGGACTCATCTAGGATGTACAAGGAATCAATGATGGGAAGCATTCGTGGC
AAGGATTCACGAGGAGAAAAAGGCGATAAAGGCGATATGGGTATGAAAGGAATGAAGGGA
GAAGGTGGAGCAAAAGGAGAAAAAGGAGCATGTATAACAGTTCCAGAAATACAGACTAAC
AATTGCGGTTGTCCATTCAATGATACATACAAAGGAATAAAGGGAGATAAAGGGCTTAGA
GGAAAACGTGGAAAAACTGGCAGTCAAGGAGAAAAAGGACAGAAAGGAGATAGTGGGTCA
TCAGTGGGGCCAAAAGGTGACAAAGGAGAGCGAGGTCAACCAGGTCTGCCAGGACCACCT
TTTAGTGGCTTTGATGACTCAATGAATTATCAACGATCAGGAATCGGCACAATAATCACA
TTTCAAAATACTGACACAATGATAAAACAATCATCTACATATCCTGTAGGTTCAATTTGT
TATGTTATAGATGAGGAAGCTCTGTTAGTGAAAGTTTCAAAAGGATGGCAATACATTGCT
CTTGGCACATTATTACCATTCACAACTCCTTATGTAACCACTTCACCAATGTCTCCAACT
TCCTACATGGACCTTCAAGCTTCAAATTTGCTCAACAGTAACAGTATTTTAAAGTCTCCT
GAGAGCTATACATTTACAACACCTCCAGAATATGAAACATGGAATCCAAAAATGTTAAGA
TTGATTGCATTGAATGAACCATACTCTGGTAATTTACAAGGTTTACGAAACGCTGATTTA
AATTGTCATCGACAAGCAAGACGATCTGGATTGATGGGTAACTTTAGAGCTTTCTTATCA
ACTAGAATTCAGAACTTGGATTCTCTAATAAAACCCGAAGACAGAGAATTGCCAATAACA
AACTTGCGTGGGGATGTGCTTTTTAATTCATTCAACGCTATTTTCAATAATAATGCTCAA
GGAATCTTTCTGTCATCCAATTCACCGCGAATTATTAGCTTCAGTGGCAAAAATGTGATG
AATGACAATACTTGGCCTCATAAAATTGTTTGGCATGGCGCACGTGCGGATTCAATAGAC
ACAAATTGTGAAGGTTGGCATAGCAATTTTCAAGATAAGGTTGGTTTAGGGAGCAGTCTG
TTAGGAAATAAGTTACTTGCTCAAGAAATGTATAGTTGTCAGCAAAAGAATATTGTTCTA
TGCATTGAAGTGTTATCGCATAGTAGCAGTGGTGATATTGCAAATCGTCGAAAGCGTGAG
ATGATGCAGAGTAATGACGATACATACGACAACGAAAAATGA
>g11445.t1 Gene=g11445 Length=633
MAMVISSRAKGMIGAFISLILLSTVLVTASTKGWWFGLNKNNGEHVAARIQANSDSDFND
YSNENESPVLQAPPDFKNYGGYRKGEKGEKGARGIPGDSIRGPPGPPGPKGECQIVNFNN
NTNSYNNNFKQTEQKLAPVCACNYDNIIDILHNESVIQILRGPQGPPGLTGAPGQKGEMG
ERGADGIDGIPGLPGTPGESSSNWDSSRMYKESMMGSIRGKDSRGEKGDKGDMGMKGMKG
EGGAKGEKGACITVPEIQTNNCGCPFNDTYKGIKGDKGLRGKRGKTGSQGEKGQKGDSGS
SVGPKGDKGERGQPGLPGPPFSGFDDSMNYQRSGIGTIITFQNTDTMIKQSSTYPVGSIC
YVIDEEALLVKVSKGWQYIALGTLLPFTTPYVTTSPMSPTSYMDLQASNLLNSNSILKSP
ESYTFTTPPEYETWNPKMLRLIALNEPYSGNLQGLRNADLNCHRQARRSGLMGNFRAFLS
TRIQNLDSLIKPEDRELPITNLRGDVLFNSFNAIFNNNAQGIFLSSNSPRIISFSGKNVM
NDNTWPHKIVWHGARADSIDTNCEGWHSNFQDKVGLGSSLLGNKLLAQEMYSCQQKNIVL
CIEVLSHSSSGDIANRRKREMMQSNDDTYDNEK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g11445.t1 | Gene3D | G3DSA:1.20.5.320 | - | 83 | 135 | 2.5E-5 |
| 11 | g11445.t1 | Gene3D | G3DSA:2.10.10.50 | - | 337 | 377 | 1.6E-6 |
| 13 | g11445.t1 | Gene3D | G3DSA:3.10.100.10 | - | 432 | 605 | 7.7E-61 |
| 22 | g11445.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 86 | 107 | - |
| 21 | g11445.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 215 | 236 | - |
| 24 | g11445.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 215 | 247 | - |
| 20 | g11445.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 275 | 290 | - |
| 23 | g11445.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 275 | 313 | - |
| 6 | g11445.t1 | PANTHER | PTHR24023:SF965 | COLLAGEN TYPE XVIII ALPHA 1 CHAIN B | 75 | 117 | 2.0E-56 |
| 8 | g11445.t1 | PANTHER | PTHR24023 | COLLAGEN ALPHA | 75 | 117 | 2.0E-56 |
| 5 | g11445.t1 | PANTHER | PTHR24023:SF965 | COLLAGEN TYPE XVIII ALPHA 1 CHAIN B | 162 | 597 | 2.0E-56 |
| 7 | g11445.t1 | PANTHER | PTHR24023 | COLLAGEN ALPHA | 162 | 597 | 2.0E-56 |
| 3 | g11445.t1 | Pfam | PF01391 | Collagen triple helix repeat (20 copies) | 162 | 199 | 2.2E-7 |
| 4 | g11445.t1 | Pfam | PF01391 | Collagen triple helix repeat (20 copies) | 272 | 319 | 6.5E-7 |
| 2 | g11445.t1 | Pfam | PF06482 | Collagenase NC10 and Endostatin | 339 | 393 | 3.7E-7 |
| 1 | g11445.t1 | Pfam | PF06482 | Collagenase NC10 and Endostatin | 427 | 604 | 4.7E-58 |
| 15 | g11445.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 29 | - |
| 16 | g11445.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 12 | - |
| 17 | g11445.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 13 | 24 | - |
| 18 | g11445.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 25 | 29 | - |
| 14 | g11445.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 30 | 633 | - |
| 9 | g11445.t1 | SUPERFAMILY | SSF56436 | C-type lectin-like | 437 | 603 | 5.02E-51 |
| 10 | g11445.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 29 | - |
| 19 | g11445.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 13 | 35 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K06823 (collagen type XVIII alpha)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
