General information for g11456.t85
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Hsp90 co-chaperone Cdc37.
Parent gene
- The parent gene g11456 is located on chr_1: 16359059..16361209 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11456 | g11456.t85 | TTS | g11456.t85 | 16358079 | 16358079 |
| chr_1 | g11456 | g11456.t85 | isoform | g11456.t85 | 16358239 | 16359529 |
| chr_1 | g11456 | g11456.t85 | exon | g11456.t85.exon1 | 16358239 | 16358439 |
| chr_1 | g11456 | g11456.t85 | cds | g11456.t85.CDS1 | 16358239 | 16358439 |
| chr_1 | g11456 | g11456.t85 | exon | g11456.t85.exon2 | 16358577 | 16359529 |
| chr_1 | g11456 | g11456.t85 | cds | g11456.t85.CDS2 | 16358577 | 16359350 |
| chr_1 | g11456 | g11456.t85 | TSS | g11456.t85 | 16359617 | 16359617 |
Sequences
>g11456.t85 Gene=g11456 Length=1154
ATGGTCGATTACTCAAAGTGGAAGAATATTGAAGTATCTGATGATGAAGATGGTAAGGTT
TTTATGCAATTCACATCAAGAACTAGCTAAAATTTGTTTTTTTAGATACTCATCCAAATA
TCGATACACCAAGTCTTTTTCGTTGGAGGCATCAGGCAAGAATTGAACGTATGGAAGAAA
TGGAACAGCAAAAAAAGCAATTGGAATCAGCAATTAAAGAGAATGAAAAGTTGCTAAATG
ATTTGAAGGAAAAATTAAAAATATCACCCGAGGACAAAAAACTTACAGATGAAATTAAAA
AACAAGAAGCCGAAAGAATTAAATTAATGGATGTTCAGAAAGATCTTAAGAAGAAAGAAC
AATTGGCTCCATGGAATGTTGACACATTATCTCAACCCAAATTTTCAAAAACAGTTATCA
ATAAAAAGGATGAGAGAAATTATGAAGAAATGACAGATGAAGAAAAGGAACAGCACATGA
AAAAGTTTGTTAAAGAAAATGAAGCACTTATGAAACAATTTGGAATGTTGCGCAAATTCG
ATGATTCTAAAACTTTCTTAATGAAACATACCTCTTTGGTACACGAAGATACTGCAAATT
ATCTCGTTATTTGGTGCATTAATTTAGAAATGGAAGAGAAGCATGAACTGATGACACATG
TTGCTCATCAATGCATTTGTATGCAATACATGCTTGAACTTTCTAAACAACTTAAAATTG
ATCCTCGAGCATGTATTGCTCCATTTTTTGAGAGAATTCAAACTGCTGATGTTGAGTACA
AACGTCAATTTGAAGATGAAATTGCTGCATTTATCGGTCGTATTGAGAGACGAGCAAAGG
AGAAAATTGCAGAAGCTCTTAAAGAACAAGAGGAAGAAGAAAAACGCGAGAGACTTGCAC
GACTTGGACCTGGCGGTTTGGATCCAGCTGAAGTTTTTGAAACATTGCCCAAGGATCTTC
AAGTTTGTTTTGAAACTCGTGATACAGAAATGCTAAAGGAAGTAATTTCAAAAATGCCAG
AAGATGAAGCAAAATATCACATGAAGCGTTGTGTAGATTCTGGTTTATGGGTACCTGATG
CAAGTCAACTACCATCATCTGAAAATGAGGAAGAAAATAAAACAACTCAAAACAACGATT
TGGATTTGGATTAA
>g11456.t85 Gene=g11456 Length=324
MEQQKKQLESAIKENEKLLNDLKEKLKISPEDKKLTDEIKKQEAERIKLMDVQKDLKKKE
QLAPWNVDTLSQPKFSKTVINKKDERNYEEMTDEEKEQHMKKFVKENEALMKQFGMLRKF
DDSKTFLMKHTSLVHEDTANYLVIWCINLEMEEKHELMTHVAHQCICMQYMLELSKQLKI
DPRACIAPFFERIQTADVEYKRQFEDEIAAFIGRIERRAKEKIAEALKEQEEEEKRERLA
RLGPGGLDPAEVFETLPKDLQVCFETRDTEMLKEVISKMPEDEAKYHMKRCVDSGLWVPD
ASQLPSSENEEENKTTQNNDLDLD
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g11456.t85 | Coils | Coil | Coil | 1 | 28 | - |
| 10 | g11456.t85 | Coils | Coil | Coil | 39 | 59 | - |
| 11 | g11456.t85 | Coils | Coil | Coil | 216 | 240 | - |
| 9 | g11456.t85 | Gene3D | G3DSA:1.20.58.610 | - | 99 | 228 | 9.7E-57 |
| 8 | g11456.t85 | MobiDBLite | mobidb-lite | consensus disorder prediction | 299 | 324 | - |
| 3 | g11456.t85 | PANTHER | PTHR12800:SF3 | HSP90 CO-CHAPERONE CDC37 | 3 | 315 | 1.5E-95 |
| 4 | g11456.t85 | PANTHER | PTHR12800 | CDC37-RELATED | 3 | 315 | 1.5E-95 |
| 1 | g11456.t85 | Pfam | PF08565 | Cdc37 Hsp90 binding domain | 114 | 225 | 5.4E-23 |
| 2 | g11456.t85 | Pfam | PF08564 | Cdc37 C terminal domain | 246 | 316 | 1.6E-14 |
| 7 | g11456.t85 | SMART | SM01070 | CDC37_M_2 | 76 | 234 | 8.6E-59 |
| 6 | g11456.t85 | SMART | SM01069 | CDC37_C_2 | 241 | 315 | 9.1E-32 |
| 5 | g11456.t85 | SUPERFAMILY | SSF101391 | Hsp90 co-chaperone CDC37 | 100 | 301 | 2.48E-70 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed