General information for g11491.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Unconventional myosin IC.
Parent gene
- The parent gene g11491 is located on chr_1: 16598572..16599945 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11491 | g11491.t1 | TTS | g11491.t1 | 16595830 | 16595830 |
| chr_1 | g11491 | g11491.t1 | isoform | g11491.t1 | 16596025 | 16599945 |
| chr_1 | g11491 | g11491.t1 | exon | g11491.t1.exon1 | 16596025 | 16596039 |
| chr_1 | g11491 | g11491.t1 | cds | g11491.t1.CDS1 | 16596025 | 16596039 |
| chr_1 | g11491 | g11491.t1 | exon | g11491.t1.exon2 | 16596094 | 16596199 |
| chr_1 | g11491 | g11491.t1 | cds | g11491.t1.CDS2 | 16596094 | 16596199 |
| chr_1 | g11491 | g11491.t1 | exon | g11491.t1.exon3 | 16596266 | 16596579 |
| chr_1 | g11491 | g11491.t1 | cds | g11491.t1.CDS3 | 16596266 | 16596579 |
| chr_1 | g11491 | g11491.t1 | exon | g11491.t1.exon4 | 16596635 | 16598104 |
| chr_1 | g11491 | g11491.t1 | cds | g11491.t1.CDS4 | 16596635 | 16598104 |
| chr_1 | g11491 | g11491.t1 | exon | g11491.t1.exon5 | 16598168 | 16598197 |
| chr_1 | g11491 | g11491.t1 | cds | g11491.t1.CDS5 | 16598168 | 16598197 |
| chr_1 | g11491 | g11491.t1 | exon | g11491.t1.exon6 | 16598263 | 16598514 |
| chr_1 | g11491 | g11491.t1 | cds | g11491.t1.CDS6 | 16598263 | 16598514 |
| chr_1 | g11491 | g11491.t1 | exon | g11491.t1.exon7 | 16598572 | 16598787 |
| chr_1 | g11491 | g11491.t1 | cds | g11491.t1.CDS7 | 16598572 | 16598787 |
| chr_1 | g11491 | g11491.t1 | exon | g11491.t1.exon8 | 16598850 | 16599036 |
| chr_1 | g11491 | g11491.t1 | cds | g11491.t1.CDS8 | 16598850 | 16599036 |
| chr_1 | g11491 | g11491.t1 | exon | g11491.t1.exon9 | 16599092 | 16599296 |
| chr_1 | g11491 | g11491.t1 | cds | g11491.t1.CDS9 | 16599092 | 16599296 |
| chr_1 | g11491 | g11491.t1 | exon | g11491.t1.exon10 | 16599354 | 16599424 |
| chr_1 | g11491 | g11491.t1 | cds | g11491.t1.CDS10 | 16599354 | 16599424 |
| chr_1 | g11491 | g11491.t1 | exon | g11491.t1.exon11 | 16599629 | 16599744 |
| chr_1 | g11491 | g11491.t1 | cds | g11491.t1.CDS11 | 16599629 | 16599744 |
| chr_1 | g11491 | g11491.t1 | exon | g11491.t1.exon12 | 16599820 | 16599945 |
| chr_1 | g11491 | g11491.t1 | cds | g11491.t1.CDS12 | 16599820 | 16599945 |
| chr_1 | g11491 | g11491.t1 | TSS | g11491.t1 | 16600046 | 16600046 |
Sequences
>g11491.t1 Gene=g11491 Length=3108
ATGGAGAGAGAAATTTATGATCGCGACCGTGCCGGTGTATCTGATGCAGTTTTATTAGAA
GACTATACAAGTGATGACGTATTTATTGCCAATCTTCAGAAACGATTCCATGAAAATATC
ATTTACACATATATTGGTCAAGTACTTGTTTCTGTAAATCCATATAAAGAACTTCCAATT
TATTCTGAGCAGGATATTCAAACATATAGAAAGAAATATTTCTTCGAGAATCCTCCCCAT
GTTTTTGCCACAAGTGATAACGCTTTTCGTTTACTTATTGAAGAAAATCGTAGTCAATGT
ATTTTGATATCAGGTGAGAGTGGCAGTGGTAAGACTGAGAATTCAAAGAAAATTTTACAG
TACATAGCAGCAGCTTCTGGCCATGTCGAAAGCGTTGAATCTGTGAAGGACAAATTGTTA
CAAACTAATCCAATTTTGGAGGCCTTTGGTAATGCCAAGACTAACAGAAATAACAATTCT
TCGAGATTTGGAAAGTATATGGATATAAATTTTAACTGGCAAGGAGTCCCAGATGGTGGA
GACATTTTAAACTATCTTCTTGAAAAATCGCGTATTGTTCATCAAAATGCAAACGAGAGA
AATTTCCACATTTTTTATCAGCTTCTAAGTGGCGGTGATGAGCAGCTTTTAGAAAAATTG
CATCTTAAGCGCAATTTTGCAGATTATTCATATATAAGTGGTGGCGACATTTTGCCAAGC
ACAGATAAGAACTTGGACGATGCAAACAATTTTAAAGTAGTGATGAATGCAATGAATACT
ATTGAAATTCCTAAAGAAGAACAAGATGAATTACTTGATATTGTTGCAAGTGTATTGCAT
TTGGGAAATATTACTTTCGGTGTCGGTGAAAAAGGTCATAGCACAGTTTATGAAAATGAA
GCAGTTCATGCTTTTGCAAATATACTTGGAATTGAATTTGATCAAGTTAAGAAATGTCTT
ACTCATCGTACAATCGATGCTCATGGTGATCTTGTCACATCACCTCTTAACCGTGATCAA
AGTTTTTATGCACGTGATGCACTTGCAAAAGCTATGTATGCACGAGTCTTTGATTGGCTC
GTTGAAACCATCAATAAGTCAATTCATACACCAACAAGTACTTCAAGAGTAAAAACTAAT
CATGTTCTTGGTGTGCTTGATATTTATGGATTTGAGGTCTTTGAAACGAACACATATGAA
CAGTTATGCATCAATTTTTGTAATGAAAAGTTACAACAATTATTTATTGAATTGACATTG
AAGCAAGAACAAGAAGAATATTTGAAAGAAGGAATAGAGTGGACTCCAGTGGAATATTTC
AATAATAAAATAATTTGTGATCTTATTGAAGAGAAGCATGTCGGCATTATCTCATTGCTA
GATGAAGAATGCTTAAGACCCGGGGATGCAACCGATTTGACATTCTTAGAAAAAATGAAT
GAACGTCTTGCATCACATCCGCATTATATTTTCAACAGTTCAAGAGCAAGTCTAGTCATC
CAAAAACTCGTGCATCGAGATGAATTTCAATTGAGACATTATGCGGGTGATGTCAAATAT
AATGTTGATGGATTTTTGGACAAAAATAGTGATTTGCTATTTCGAGATTTGAAAGAAGCT
ATGTCAGCATCAAAGAATAGTATCATCAAACTCCTCTTTCCATCTAGTGAATTTTTATTA
TCAAGAAAAAGACCTGATACTGCCATAACACAATTTAAAAATTCACTTAACAATTTGATG
CAAATTTTGGCATCAAAAGAACCAAGCTACATACGTTGCATCAAACCCAATCAACTGCAA
ACATCAGATAATTTTGATTTTGAACTAGTACGTCATCAAGTCAAATATTTGGGCTTAATG
GAAAATTTGAGAGTTAGACGAGCTGGTTTTGCATATCGTCGAACTTACGATGCATTCTTA
GAACGCTACAAGTGTCTCAGCAAGCAAACATGGCCAAATTTCAAGGGAAATCCTCGTGAT
GGTGTTCAAATTATTGCTAATGAGCTAAACTATGGCGCCGATGATTATCGAATGGGAAAA
ACAAAAGTTTTCATTCGCCTTCCTCAAACTCTCTTTATGACTGAAGACGCATTTCAGTTA
AAGAAAAATTATGTGGCATCAATCATTCAGGCGCGTTGGAAAGGGAAAATTCAACGAAGA
AAATATTTGGAATTGCGTGAGTCTGTTATCATCACTCAATCCTATTGTCGAAGAGTTTTG
GCAAAAAGACGATTGGCAGAACGCAAAGGCGCAGTTGAACGAATTAGATTCTTCATCAAA
GGATTTATTACACGCAATCAAGCACCTAATGAATGCAATGCAAAATTTATTCAACTTGTC
AAACAAATGTGGTTGATTCGTTTGTCTAAATCACTTCCAAATAGCTTTATGAATCATTCA
TGGCCAAAACCATCAGCTCATTGTGAAGAAGCATCAGAACATTTGAAAAAAATGCATTTG
CTCTATTTAGCAAAAAGATATCGTGATCGTTTGACACCTGAAAGAAAAGCAGCATTTGAT
ATGAAAGTCCTTGCAGAGTCTGTTTTTAAAGGTGCAAAGAGAAGCTATCCAAAGAGTATC
CCACATTGGTTTATTAATGATAGGGTAGTTGATCATCATCAAGCTCAAATTAAAAGCTTT
ATTAAAAGTCCTACATTTGGTGAAAGAGTTATTTATCAAACATCTTGCATGAAATATGAC
CGTCGCGGATATAAGCCACGAGAGAGAATTTTAATCATTGGTGATAAAAGTTTGTTCTTG
ATTGATGCAAAAACTTACAAACAAAAACACCGCATTAGTCTGAATAAAATTCCCAACATT
GTATTAACAAAAGAAGGTGATAATTTGCTACTAGTAAGAATTCCACTTGAGTTGAAAAAA
GATAAGGGTGATTTGATTCTTGACGTGCCATACATTATTGAGTGCTGCACATGGTGGATA
AAAGCAACAAATAACATAAATATTATTCAGATTACAGATAGTGCTACATTCTCACATAAT
ATGACTTCAGGAAAGAGTGGTGTGATTCAAGTTGAATTAGGTACTGCAAGCATAACAACA
ATAACAAAAGCTAAATCAGGAAATTTGCTTGTGATTGCTGCTCAATAA
>g11491.t1 Gene=g11491 Length=1035
MEREIYDRDRAGVSDAVLLEDYTSDDVFIANLQKRFHENIIYTYIGQVLVSVNPYKELPI
YSEQDIQTYRKKYFFENPPHVFATSDNAFRLLIEENRSQCILISGESGSGKTENSKKILQ
YIAAASGHVESVESVKDKLLQTNPILEAFGNAKTNRNNNSSRFGKYMDINFNWQGVPDGG
DILNYLLEKSRIVHQNANERNFHIFYQLLSGGDEQLLEKLHLKRNFADYSYISGGDILPS
TDKNLDDANNFKVVMNAMNTIEIPKEEQDELLDIVASVLHLGNITFGVGEKGHSTVYENE
AVHAFANILGIEFDQVKKCLTHRTIDAHGDLVTSPLNRDQSFYARDALAKAMYARVFDWL
VETINKSIHTPTSTSRVKTNHVLGVLDIYGFEVFETNTYEQLCINFCNEKLQQLFIELTL
KQEQEEYLKEGIEWTPVEYFNNKIICDLIEEKHVGIISLLDEECLRPGDATDLTFLEKMN
ERLASHPHYIFNSSRASLVIQKLVHRDEFQLRHYAGDVKYNVDGFLDKNSDLLFRDLKEA
MSASKNSIIKLLFPSSEFLLSRKRPDTAITQFKNSLNNLMQILASKEPSYIRCIKPNQLQ
TSDNFDFELVRHQVKYLGLMENLRVRRAGFAYRRTYDAFLERYKCLSKQTWPNFKGNPRD
GVQIIANELNYGADDYRMGKTKVFIRLPQTLFMTEDAFQLKKNYVASIIQARWKGKIQRR
KYLELRESVIITQSYCRRVLAKRRLAERKGAVERIRFFIKGFITRNQAPNECNAKFIQLV
KQMWLIRLSKSLPNSFMNHSWPKPSAHCEEASEHLKKMHLLYLAKRYRDRLTPERKAAFD
MKVLAESVFKGAKRSYPKSIPHWFINDRVVDHHQAQIKSFIKSPTFGERVIYQTSCMKYD
RRGYKPRERILIIGDKSLFLIDAKTYKQKHRISLNKIPNIVLTKEGDNLLLVRIPLELKK
DKGDLILDVPYIIECCTWWIKATNNINIIQITDSATFSHNMTSGKSGVIQVELGTASITT
ITKAKSGNLLVIAAQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 17 | g11491.t1 | CDD | cd01378 | MYSc_Myo1 | 28 | 686 | 0.0000000 |
| 14 | g11491.t1 | Gene3D | G3DSA:3.40.850.10 | Kinesin | 22 | 629 | 0.0000000 |
| 13 | g11491.t1 | Gene3D | G3DSA:1.10.10.820 | - | 200 | 259 | 0.0000000 |
| 12 | g11491.t1 | Gene3D | G3DSA:1.20.120.720 | - | 260 | 367 | 0.0000000 |
| 16 | g11491.t1 | Gene3D | G3DSA:1.20.58.530 | - | 394 | 586 | 0.0000000 |
| 11 | g11491.t1 | Gene3D | G3DSA:3.30.70.3240 | - | 630 | 696 | 0.0000000 |
| 15 | g11491.t1 | Gene3D | G3DSA:1.20.5.190 | - | 701 | 753 | 0.0000085 |
| 3 | g11491.t1 | PANTHER | PTHR13140:SF353 | UNCONVENTIONAL MYOSIN-IH | 6 | 985 | 0.0000000 |
| 4 | g11491.t1 | PANTHER | PTHR13140 | MYOSIN | 6 | 985 | 0.0000000 |
| 8 | g11491.t1 | PRINTS | PR00193 | Myosin heavy chain signature | 42 | 61 | 0.0000000 |
| 5 | g11491.t1 | PRINTS | PR00193 | Myosin heavy chain signature | 98 | 123 | 0.0000000 |
| 9 | g11491.t1 | PRINTS | PR00193 | Myosin heavy chain signature | 144 | 171 | 0.0000000 |
| 7 | g11491.t1 | PRINTS | PR00193 | Myosin heavy chain signature | 382 | 410 | 0.0000000 |
| 6 | g11491.t1 | PRINTS | PR00193 | Myosin heavy chain signature | 435 | 463 | 0.0000000 |
| 1 | g11491.t1 | Pfam | PF00063 | Myosin head (motor domain) | 17 | 686 | 0.0000000 |
| 2 | g11491.t1 | Pfam | PF06017 | Unconventional myosin tail, actin- and lipid-binding | 842 | 1025 | 0.0000000 |
| 22 | g11491.t1 | ProSiteProfiles | PS51456 | Myosin motor domain profile. | 12 | 699 | 250.8320000 |
| 23 | g11491.t1 | ProSiteProfiles | PS50096 | IQ motif profile. | 702 | 729 | 7.3460000 |
| 21 | g11491.t1 | ProSiteProfiles | PS51757 | Class I myosin tail homology (TH1) domain profile. | 853 | 1035 | 19.7600000 |
| 20 | g11491.t1 | SMART | SM00242 | MYSc_2a | 5 | 700 | 0.0000000 |
| 18 | g11491.t1 | SMART | SM00015 | iq_5 | 701 | 723 | 7.5000000 |
| 19 | g11491.t1 | SMART | SM00015 | iq_5 | 724 | 746 | 1.8000000 |
| 10 | g11491.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 10 | 752 | 0.0000000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0005515 | protein binding | MF |
| GO:0016459 | myosin complex | CC |
| GO:0003774 | cytoskeletal motor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K10356 (myosin I)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed