General information for g11530.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Kinesin-like protein KIF3A.
Parent gene
- The parent gene g11530 is located on chr_1: 16878838..16881393 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11530 | g11530.t1 | TTS | g11530.t1 | 16878585 | 16878585 |
| chr_1 | g11530 | g11530.t1 | isoform | g11530.t1 | 16878838 | 16881393 |
| chr_1 | g11530 | g11530.t1 | exon | g11530.t1.exon1 | 16878838 | 16879935 |
| chr_1 | g11530 | g11530.t1 | cds | g11530.t1.CDS1 | 16878838 | 16879935 |
| chr_1 | g11530 | g11530.t1 | exon | g11530.t1.exon2 | 16880044 | 16880560 |
| chr_1 | g11530 | g11530.t1 | cds | g11530.t1.CDS2 | 16880044 | 16880560 |
| chr_1 | g11530 | g11530.t1 | exon | g11530.t1.exon3 | 16880655 | 16880762 |
| chr_1 | g11530 | g11530.t1 | cds | g11530.t1.CDS3 | 16880655 | 16880762 |
| chr_1 | g11530 | g11530.t1 | exon | g11530.t1.exon4 | 16880882 | 16880979 |
| chr_1 | g11530 | g11530.t1 | cds | g11530.t1.CDS4 | 16880882 | 16880979 |
| chr_1 | g11530 | g11530.t1 | exon | g11530.t1.exon5 | 16881382 | 16881393 |
| chr_1 | g11530 | g11530.t1 | cds | g11530.t1.CDS5 | 16881382 | 16881393 |
| chr_1 | g11530 | g11530.t1 | TSS | g11530.t1 | NA | NA |
Sequences
>g11530.t1 Gene=g11530 Length=1833
ATGAATGAACGAATTGACTTGTACATTAATACAGCGAGACCCATTGTAGATAAAGTTCTA
GAAGGTTATAATGGAACAATTTTGGCATACGGTCAAACTGGTACTGGCAAAACTTACACG
ATGGTTGGAAATGCAGATTCACCAGAAACAAGAGGCATCATTCCAAATAGCTTTGCACAT
ATATTTGGTCATATAGCGAAAGCCAAAGAAAATGAAAAATTTCTCGTGCGTGTAAGCTAT
ATGGAAATTTATAATGAAGAAGTTCGAGATTTACTTGGAAAAGAACTAAATAAAAGTCTT
GAAGTGAAAGAACGATCAGATATTGGTGTGTTTGTGAAAGATCTCTCGGGTTATGTTGTT
CACAATGCGGACGATTTGGATAACATTATGAAACTGGGCAACAAAAACAGGGCTGTTGGT
TCTACTTTAGTAAATCAACAATCATCGCGATCTCACGCAATTTTCTCTATTACAATTGAA
TCATCGTTGACGGTTGATAATGACACTAAAGTTAAAATGGGAAAACTTCAATTAGTCGAT
TTAGCTGGCTCTGAACGACAAAGCAAGACACAAGCTAGTGGAATTCGTCTAAAAGAGGCC
ACTAAGATCAACCTTTCACTCTCCGTATTAGGTAATGTTATTTCAGCACTCGTCGATGGT
AAAAGTTCTCATATTCCGTATCGTAATTCAAAACTTACTCGATTGTTACAAGATTCACTT
GGTGGCAATTCAAAGACACTTATGTGTGCAACAATTTCGCCATCAGAGTCAAATTACGTT
GAAACAATTTCAACATTGCGCTATGCTGGTCGTGCAAAGAGCATTCAAAATCATGCTCAT
ATGAATTTCGATCCTAAAGATGCTTTATTGAAGCATTTTCAACAAGAAATTGAAGAATTG
AAACGTCAATTAGAAGAAGGAGTTTTTGAGATAGGTGGTGATGAAATTGATGCAGATGAA
AATGATGATTTAAGCGAAGAATCAGATATTGAGATAGAAAATGAGAAAGAAAAGAGTAAA
GAAAAAAGCAAAAAGAAAAAGGCTAAAGCAAATAAAGACGAAATGCACAAAGAAAAATCT
GACGCAGAAAAAGAATTACTTGAGCTCAAAGCACAAGAACATGAAAAAGCGTTAAAGGTA
GCACAGTCAGAGCAAGATATAATTAGAGCCAAACTTCAATCTCTTGAAAATAAAATTTTA
AATGGTGGTGAGAATTTGTTAGAGAAAGCAAACCAACAGGAGCAACTTTTGGAAAAATCA
ATCGCAGAACTTGAAGCCACAAATAAGAAAGAACAAGAACTACAACAAACACTTCAGAAA
ATTGAGGCTGAACGAATTGACATTGAAGAACGATATTCTTCGCTTCAAGAAGAATGTGTT
GGAAAGACTAAGAAATTACAGAAAGTTATGCAAATGCTTATGGGTTTGAAATCAGAATTA
GCTGATCAACAGCAAGAACAGCAACGTGAAAAAGAGGGAATTTATGAAAATATTCGTAGT
TTGTCAAGAGAACTTGCTCTTTGTGAACTTGTTATTAACAATTATATACCGAAAGAATAT
CAAACATTGATTGACAAGTTCACTTACTGGAACGAAGAGATTGGCGAGTGGCAATTGAAA
TGTGTTGCATATACCGGTAACAATATGCGCAAAAACATTAATGAACAACAGAAAAATGCT
AAAGAAGAAAAAGAATATGTTGATTTGAGCCATGTCTATTTAAGTTACAATGTTGACGGA
TTAACTGAGCCGGTTCGCGGAAAAACATCTCGACCTAAAACATCACATTCTGGTGTACCA
CGCTATTACCAAAGAATTAATAATATAAATTAG
>g11530.t1 Gene=g11530 Length=610
MNERIDLYINTARPIVDKVLEGYNGTILAYGQTGTGKTYTMVGNADSPETRGIIPNSFAH
IFGHIAKAKENEKFLVRVSYMEIYNEEVRDLLGKELNKSLEVKERSDIGVFVKDLSGYVV
HNADDLDNIMKLGNKNRAVGSTLVNQQSSRSHAIFSITIESSLTVDNDTKVKMGKLQLVD
LAGSERQSKTQASGIRLKEATKINLSLSVLGNVISALVDGKSSHIPYRNSKLTRLLQDSL
GGNSKTLMCATISPSESNYVETISTLRYAGRAKSIQNHAHMNFDPKDALLKHFQQEIEEL
KRQLEEGVFEIGGDEIDADENDDLSEESDIEIENEKEKSKEKSKKKKAKANKDEMHKEKS
DAEKELLELKAQEHEKALKVAQSEQDIIRAKLQSLENKILNGGENLLEKANQQEQLLEKS
IAELEATNKKEQELQQTLQKIEAERIDIEERYSSLQEECVGKTKKLQKVMQMLMGLKSEL
ADQQQEQQREKEGIYENIRSLSRELALCELVINNYIPKEYQTLIDKFTYWNEEIGEWQLK
CVAYTGNNMRKNINEQQKNAKEEKEYVDLSHVYLSYNVDGLTEPVRGKTSRPKTSHSGVP
RYYQRINNIN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g11530.t1 | Coils | Coil | Coil | 290 | 310 | - |
| 10 | g11530.t1 | Coils | Coil | Coil | 338 | 398 | - |
| 11 | g11530.t1 | Coils | Coil | Coil | 407 | 458 | - |
| 13 | g11530.t1 | Coils | Coil | Coil | 466 | 504 | - |
| 9 | g11530.t1 | Gene3D | G3DSA:3.40.850.10 | Kinesin | 2 | 294 | 2.1E-127 |
| 17 | g11530.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 312 | 362 | - |
| 18 | g11530.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 312 | 330 | - |
| 16 | g11530.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 331 | 362 | - |
| 2 | g11530.t1 | PANTHER | PTHR24115:SF472 | KINESIN-LIKE PROTEIN KIF3A | 5 | 579 | 1.6E-205 |
| 3 | g11530.t1 | PANTHER | PTHR24115 | KINESIN-RELATED | 5 | 579 | 1.6E-205 |
| 7 | g11530.t1 | PRINTS | PR00380 | Kinesin heavy chain signature | 22 | 43 | 5.6E-43 |
| 4 | g11530.t1 | PRINTS | PR00380 | Kinesin heavy chain signature | 142 | 159 | 5.6E-43 |
| 6 | g11530.t1 | PRINTS | PR00380 | Kinesin heavy chain signature | 175 | 193 | 5.6E-43 |
| 5 | g11530.t1 | PRINTS | PR00380 | Kinesin heavy chain signature | 225 | 246 | 5.6E-43 |
| 1 | g11530.t1 | Pfam | PF00225 | Kinesin motor domain | 6 | 275 | 1.9E-106 |
| 15 | g11530.t1 | ProSitePatterns | PS00411 | Kinesin motor domain signature. | 174 | 185 | - |
| 19 | g11530.t1 | ProSiteProfiles | PS50067 | Kinesin motor domain profile. | 1 | 275 | 113.3 |
| 14 | g11530.t1 | SMART | SM00129 | kinesin_4 | 4 | 283 | 9.3E-127 |
| 8 | g11530.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 6 | 305 | 2.25E-110 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:1990939 | NA | NA |
| GO:0007018 | microtubule-based movement | BP |
| GO:0005524 | ATP binding | MF |
| GO:0003777 | microtubule motor activity | MF |
| GO:0008017 | microtubule binding | MF |
KEGG
Orthology
- This transcript has been annotated with K10394 (kinesin family member 3A)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
