General information for g11619.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Septin-2.
Parent gene
- The parent gene g11619 is located on chr_1: 17476238..17477313 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11619 | g11619.t2 | TTS | g11619.t2 | 17473010 | 17473010 |
| chr_1 | g11619 | g11619.t2 | isoform | g11619.t2 | 17473728 | 17475213 |
| chr_1 | g11619 | g11619.t2 | exon | g11619.t2.exon1 | 17473728 | 17473892 |
| chr_1 | g11619 | g11619.t2 | cds | g11619.t2.CDS1 | 17473728 | 17473892 |
| chr_1 | g11619 | g11619.t2 | exon | g11619.t2.exon2 | 17473961 | 17474200 |
| chr_1 | g11619 | g11619.t2 | cds | g11619.t2.CDS2 | 17473961 | 17474200 |
| chr_1 | g11619 | g11619.t2 | exon | g11619.t2.exon3 | 17474281 | 17474355 |
| chr_1 | g11619 | g11619.t2 | cds | g11619.t2.CDS3 | 17474281 | 17474355 |
| chr_1 | g11619 | g11619.t2 | exon | g11619.t2.exon4 | 17474412 | 17474897 |
| chr_1 | g11619 | g11619.t2 | cds | g11619.t2.CDS4 | 17474412 | 17474897 |
| chr_1 | g11619 | g11619.t2 | exon | g11619.t2.exon5 | 17474954 | 17475213 |
| chr_1 | g11619 | g11619.t2 | cds | g11619.t2.CDS5 | 17474954 | 17475193 |
| chr_1 | g11619 | g11619.t2 | TSS | g11619.t2 | NA | NA |
Sequences
>g11619.t2 Gene=g11619 Length=1226
TCGAAAATCATTTGCGTAATATGAAACTCTCTGGCCATGTCGGTTTCGACTCTTTGCCTG
ATCAACTCGTCAATAAAAGCGTGCAAAATGGATTTGTTTTCAACATTTTATGTATTTCTG
AAACTGGTCTTGGAAAATCGACTTTAATGGATTCTCTTTTCAATACAAATTTTGAATCGA
CACCGAGTCCTCATACTTTACCAAGTGTAAAATTAAAGGCACAAACCTTTGAGTTGCAAG
AAAGTAACGTAAGACTAAAGCTAACAATTGTGGATACTGTGGGTTATGGAGATCAAATTA
ACAAAGATGATTCATTTAAATCCTTAGTTGATTACATAGATCAACAATATGAAGCTTACT
TGCAAGAGGAGTTAAAAATCAAGAGATCACTGTCATCTTATCATGACTCGCGTATTCATG
CATGCTTATATTTCATCTGTCCAACTGGACATGGTTTAAAATCACTCGATTTAGTTTGCA
TGAAAAAACTTGATACAAAAGTTAATATCATACCGATCATTGCCAAAGCAGATACCATTT
CTAAAACAGAATTGCAAAAATTTAAAGCAAAAATCAATGAAGAATTGCAAGCAAATGGAG
TTCAAATATATCATTTTCCAACTGATGATGAAACGGTAGCTGAGCAAAATAATACCATGA
ATTCTCACATTCCATTTGCAGTTGTAGGCAGCACTGAATTTGTCAAATTAGGAAGTAAAA
TGATTCGTGCTCGTCAATATCCCTGGGGTATTGTTCAAGTCGAAGACCCTTCTCATTGCG
ATTTTGTCAAACTTCGTGAAATGTTAATAAGAACTAATATGGAAGATATGCGTGAAAAAA
CTCACACACGTCATTATGAATTATATCGTCAAAAACGTCTTGAACAAATGGGATTCACTG
ATGTCGATAGTGAAAATAAACCAGTATCATTTCAACAAACATTTGAAGCTAAGCGTTCAA
ACCATTTAGCAGAATTGCAAGCAAAAGAAGATGAAGTTCGCCAAATGTTTGTAGTGCGTG
TGAAAGAAAAAGAATCCGAATTGAAGGAAAGTGAAAAAGAGTTGCATGCCAAATTTGAAA
AGTTGAAAAAAGACCATGCTGAAGAGAAACGAAAATTAGAAGAGGCACGTAAAAAACTTG
AAGAAGAGTTTGTGGAATTTAACAGGCGTAAGACCCAATTTAGTTCAAGCCACACTTTGA
CACTTGGAAAAAATAAGAAAAAATAG
>g11619.t2 Gene=g11619 Length=401
MKLSGHVGFDSLPDQLVNKSVQNGFVFNILCISETGLGKSTLMDSLFNTNFESTPSPHTL
PSVKLKAQTFELQESNVRLKLTIVDTVGYGDQINKDDSFKSLVDYIDQQYEAYLQEELKI
KRSLSSYHDSRIHACLYFICPTGHGLKSLDLVCMKKLDTKVNIIPIIAKADTISKTELQK
FKAKINEELQANGVQIYHFPTDDETVAEQNNTMNSHIPFAVVGSTEFVKLGSKMIRARQY
PWGIVQVEDPSHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFTDVDSENK
PVSFQQTFEAKRSNHLAELQAKEDEVRQMFVVRVKEKESELKESEKELHAKFEKLKKDHA
EEKRKLEEARKKLEEEFVEFNRRKTQFSSSHTLTLGKNKKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g11619.t2 | CDD | cd01850 | CDC_Septin | 23 | 291 | 4.38393E-148 |
| 6 | g11619.t2 | Coils | Coil | Coil | 327 | 383 | - |
| 5 | g11619.t2 | Gene3D | G3DSA:3.40.50.300 | - | 1 | 291 | 4.2E-116 |
| 2 | g11619.t2 | PANTHER | PTHR18884:SF69 | LD28935P-RELATED | 1 | 384 | 2.9E-278 |
| 3 | g11619.t2 | PANTHER | PTHR18884 | SEPTIN | 1 | 384 | 2.9E-278 |
| 7 | g11619.t2 | PIRSF | PIRSF006698 | Septin | 1 | 401 | 3.3E-137 |
| 1 | g11619.t2 | Pfam | PF00735 | Septin | 23 | 291 | 3.1E-99 |
| 9 | g11619.t2 | ProSiteProfiles | PS51719 | Septin-type guanine nucleotide-binding (G) domain profile. | 23 | 289 | 103.213 |
| 4 | g11619.t2 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 8 | 263 | 6.32E-26 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005525 | GTP binding | MF |
KEGG
Orthology
- This transcript has been annotated with K16939 (septin 6/8/11)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
