Gene loci information

Transcript annotation

  • This transcript has been annotated as Elongin-C.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g11620 g11620.t1 TSS g11620.t1 17476548 17476548
chr_1 g11620 g11620.t1 isoform g11620.t1 17476781 17477313
chr_1 g11620 g11620.t1 exon g11620.t1.exon1 17476781 17476904
chr_1 g11620 g11620.t1 cds g11620.t1.CDS1 17476781 17476904
chr_1 g11620 g11620.t1 exon g11620.t1.exon2 17476968 17477034
chr_1 g11620 g11620.t1 cds g11620.t1.CDS2 17476968 17477034
chr_1 g11620 g11620.t1 exon g11620.t1.exon3 17477091 17477158
chr_1 g11620 g11620.t1 cds g11620.t1.CDS3 17477091 17477158
chr_1 g11620 g11620.t1 exon g11620.t1.exon4 17477240 17477313
chr_1 g11620 g11620.t1 cds g11620.t1.CDS4 17477240 17477313
chr_1 g11620 g11620.t1 TTS g11620.t1 17477379 17477379

Sequences

>g11620.t1 Gene=g11620 Length=333
ATGAATGAAGAAAAATATGGAGGATGTGAAGGACCTGATGCGATGTATGTGAAGTTAATT
TCATCAGATGGTCATGAGTTTATAGTCAAAAGAGAGCATGCATTAACATCAGGTACTATA
AAAGCTATGTTATCTGGTCCTGGACAGTTTGCGGAAAATGAAGCAAATGAAGTCAACTTT
AGAGAAATCCCCTCTCATGTTTTGCAAAAAGTATGCATGTATTTTACTTATAAAGTCCGA
TACACAAACAGTTCGACAGAAATTCCTGAGTTTACAATTGCACCAGAGATTGCATTGGAA
CTTTTGATGGCTGCAAACTTTCTGGATTGCTAA

>g11620.t1 Gene=g11620 Length=110
MNEEKYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENEANEVNF
REIPSHVLQKVCMYFTYKVRYTNSSTEIPEFTIAPEIALELLMAANFLDC

Protein features from InterProScan

Transcript Database ID Name Start End E.value
7 g11620.t1 CDD cd18321 BTB_POZ_EloC 16 110 0
6 g11620.t1 Gene3D G3DSA:3.30.710.10 Potassium Channel Kv1.1; Chain A 14 110 0
2 g11620.t1 PANTHER PTHR20648:SF12 - 3 110 0
3 g11620.t1 PANTHER PTHR20648 ELONGIN-C 3 110 0
1 g11620.t1 Pfam PF03931 Skp1 family, tetramerisation domain 16 78 0
5 g11620.t1 SMART SM00512 skp1_3 14 110 0
4 g11620.t1 SUPERFAMILY SSF54695 POZ domain 12 110 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006511 ubiquitin-dependent protein catabolic process BP

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values