General information for g11647.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ADP-ribose pyrophosphatase, mitochondrial.
Parent gene
- The parent gene g11647 is located on chr_1: 17612919..17613992 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11647 | g11647.t1 | TTS | g11647.t1 | 17612144 | 17612144 |
| chr_1 | g11647 | g11647.t1 | isoform | g11647.t1 | 17612919 | 17613862 |
| chr_1 | g11647 | g11647.t1 | exon | g11647.t1.exon1 | 17612919 | 17613263 |
| chr_1 | g11647 | g11647.t1 | cds | g11647.t1.CDS1 | 17612919 | 17613263 |
| chr_1 | g11647 | g11647.t1 | exon | g11647.t1.exon2 | 17613322 | 17613475 |
| chr_1 | g11647 | g11647.t1 | cds | g11647.t1.CDS2 | 17613322 | 17613475 |
| chr_1 | g11647 | g11647.t1 | exon | g11647.t1.exon3 | 17613543 | 17613862 |
| chr_1 | g11647 | g11647.t1 | cds | g11647.t1.CDS3 | 17613543 | 17613862 |
| chr_1 | g11647 | g11647.t1 | TSS | g11647.t1 | 17613971 | 17613971 |
Sequences
>g11647.t1 Gene=g11647 Length=819
ATGAATAAAATTTTTAAGCATATTGTGTGTCGTAATCAACTTTATGCAAATCAAATTCAA
AGATTTCCAGTTCCAGATGAATTTGTTCCTTGGTCAGTTAATTATGACAATTACAAACCA
CAATTTTATGAATCGCCCACATTAAATGGTAAACCATGGGCTGATGAACCATTGGACAGT
GAAAATTTTAAACCAAAATATAATCAACTTGATGGTAATGTTAACAGAAAAAGTCACATT
GGAGAATATAAAATTGTGAATCGAATGCCTCAAAATATATTTGGAAGAACAGGAATTTGT
GGTAGAGGTGTTTTAGGAAGATTTGGTCCAAATCATGCAGCAGATCCAATTGTTTCTACA
TGGAAAAGAGATGAAAATAACAAAATTGTTAAACATTCTGATGGAAAAGCAATTTTAAAA
GTTTTATGCATCCAAAGAGGTGATACTAATGAAATTGCATTGCCTGGTGGAATGGTCGAT
CCTGGAGAAAATGTTTCAGTAACACTTAAGCGGGAATTTATGGAGGAAACTTTAAACAAT
AAAATAGATGAATCAGTTCTTGATGATTTTTTTAGTCATGGAATTGAAGTTTATAAAGGC
TATATCGATGATCCTAGAAATACAGATAATGCTTGGATGGAAACTGTTGCATTCAATTTT
CACGATGAAAGTGGAGACTTTTTGAAGCAATTAAACTTTGAAGCAGGCGATGATGCAGTA
GGGATTCATTGGATTGATGTATCTCGAGATGTAAAATTATATGCAAGCCATTTAAAATTG
ATTGAAGCAACTGCGCAGTTAAGAAATGCTCATTTTTAA
>g11647.t1 Gene=g11647 Length=272
MNKIFKHIVCRNQLYANQIQRFPVPDEFVPWSVNYDNYKPQFYESPTLNGKPWADEPLDS
ENFKPKYNQLDGNVNRKSHIGEYKIVNRMPQNIFGRTGICGRGVLGRFGPNHAADPIVST
WKRDENNKIVKHSDGKAILKVLCIQRGDTNEIALPGGMVDPGENVSVTLKREFMEETLNN
KIDESVLDDFFSHGIEVYKGYIDDPRNTDNAWMETVAFNFHDESGDFLKQLNFEAGDDAV
GIHWIDVSRDVKLYASHLKLIEATAQLRNAHF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 4 | g11647.t1 | Gene3D | G3DSA:3.90.79.10 | Nucleoside Triphosphate Pyrophosphohydrolase | 112 | 272 | 0.0000000 |
| 2 | g11647.t1 | PANTHER | PTHR13030 | NUDIX HYDROLASE | 5 | 272 | 0.0000000 |
| 1 | g11647.t1 | Pfam | PF00293 | NUDIX domain | 136 | 247 | 0.0000001 |
| 5 | g11647.t1 | ProSiteProfiles | PS51462 | Nudix hydrolase domain profile. | 120 | 267 | 11.3070000 |
| 3 | g11647.t1 | SUPERFAMILY | SSF55811 | Nudix | 7 | 271 | 0.0000000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0047631 | ADP-ribose diphosphatase activity | MF |
| GO:0016787 | hydrolase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K13988 (ADP-ribose pyrophosphatase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
