General information for g11648.t7
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Ras-like protein 2.
Parent gene
- The parent gene g11648 is located on chr_1: 17619218..17620081 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11648 | g11648.t7 | TSS | g11648.t7 | 17614254 | 17614254 |
| chr_1 | g11648 | g11648.t7 | isoform | g11648.t7 | 17614363 | 17620081 |
| chr_1 | g11648 | g11648.t7 | exon | g11648.t7.exon1 | 17614363 | 17614465 |
| chr_1 | g11648 | g11648.t7 | exon | g11648.t7.exon2 | 17614812 | 17614845 |
| chr_1 | g11648 | g11648.t7 | exon | g11648.t7.exon3 | 17614897 | 17614998 |
| chr_1 | g11648 | g11648.t7 | exon | g11648.t7.exon4 | 17618780 | 17619035 |
| chr_1 | g11648 | g11648.t7 | cds | g11648.t7.CDS1 | 17618789 | 17619035 |
| chr_1 | g11648 | g11648.t7 | exon | g11648.t7.exon5 | 17619091 | 17620081 |
| chr_1 | g11648 | g11648.t7 | cds | g11648.t7.CDS2 | 17619091 | 17619218 |
| chr_1 | g11648 | g11648.t7 | TTS | g11648.t7 | 17620077 | 17620077 |
Sequences
>g11648.t7 Gene=g11648 Length=1486
ATGTCAAAGAATAATCAAACAAGTGTGCAAACTTATAAACTCGTAGTTGTTGGCAGTGGT
GGTGTCGGAAAATCCTGTATTACTATTCAATTCATTCAAGCAAAGCTACTTTTGTAGTGA
CTATGATCCGACTATAGAGGCTTTTTATCAATTTCACAGAGGATAGTTATACGAAGAGAC
TTGTAATTGATGAAGTTGTAGCAAAGCTTGATATTCTTGATACAGCAGGCCAAGAGGAGT
TTTCTGCAATGCGTGAACAATATATGAGATCGGGTGAAGGATTTCTTCTAGTATTCAGTG
TCACAGATTATGCAAGTTTCGAAGAGATTTATAAATTTCATCGACAAATTTTACGTGTGA
AAGATCGTGATGAATTTCCTATGCTTATGATTGGTAACAAGTCAGATTTAGAAGCACAAC
GAGTTGTTTCTATTGATAAAGCACAAGAACTTAGTCGTCAACTTAAAATTCCATATCTTG
AATGTAGTGCAAAAGTGAGAATCAATGTTGATCAAGCATTCATCGAACTTGTGCGTATTG
TTAGAAGATTTCAAGAATCTGAACGGCCAGTTATCAATTCAACAAAAGGAAAACCTAAAA
ATTCCAAATGCTGTCTATTATAATTTATTGATAAAAAGCCATAAAAATCCTTTAACATTT
CATCAAAGAGCATTTAATGTGCTAAATGTCAACGTTTACTTTTTAAAAATTTATGTCTAC
AATGTGTTGTTGTTATAATCAAAATGTGCCTCGTACAAATAATGTGTTTTAATAATTAAT
ATTTAAAAAAGTAATATTTTGCAATGAATCTTCCAAATATCATACATCAATATGTATAAT
CAAAGAAAACACAAAAACTTATAAATCAGTCTTGTTTATCTATATTTCTTTTCATTTAAT
AAAAACAAAAACTAATAGAAAATATTATAAATTTGGTGCTTCATAAAGAAAAAAAGAAAA
AAGGATGAACGTGTCATGCATACAAAATATAATAAGTCAATGAAGAAAATGATCATACTT
ATCAATCTACAATATGGTTCTGAATATTAACTTAATGTTGCCAAAATTTCAAGAATATAA
AAAATACAATTAAATGAAACTAGTTAGATTTAATCATGAATAACGATGTATGGTATTAGA
TAAAAAAAACTTAATGCATCTCTAATAATAACAAAAAACAAAATGTTTTACATGAATAGT
ACTCACACTGATGATTCATGAGCAGTGCAAGTAAAATAGCTTTCAAAACTAGCACATTAT
TAACTAGATTTAATGTGCCTAATCATGTGACAACAAGTATATATACATCTTAAATATCAA
CTAATTTTTGATAAAGAAAAATTTAATGATTTTTAAATCGATTCATTTTTTATTAAAAAA
TAATATCTATAGATATTTTTTTCTGAAAAATTATTAAATAGATGGTATTAAAATGTTTTT
GAAACAAAAATTAAATTAACAAAATAAATTATTAATATTTTTCAAA
>g11648.t7 Gene=g11648 Length=124
MREQYMRSGEGFLLVFSVTDYASFEEIYKFHRQILRVKDRDEFPMLMIGNKSDLEAQRVV
SIDKAQELSRQLKIPYLECSAKVRINVDQAFIELVRIVRRFQESERPVINSTKGKPKNSK
CCLL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g11648.t7 | Gene3D | G3DSA:3.40.50.300 | - | 1 | 106 | 0.0000000 |
| 2 | g11648.t7 | PANTHER | PTHR24070:SF396 | RAS-RELATED PROTEIN R-RAS2 | 1 | 122 | 0.0000000 |
| 3 | g11648.t7 | PANTHER | PTHR24070 | RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY | 1 | 122 | 0.0000000 |
| 5 | g11648.t7 | PRINTS | PR00449 | Transforming protein P21 ras signature | 41 | 54 | 0.0000000 |
| 4 | g11648.t7 | PRINTS | PR00449 | Transforming protein P21 ras signature | 76 | 98 | 0.0000000 |
| 1 | g11648.t7 | Pfam | PF00071 | Ras family | 1 | 98 | 0.0000000 |
| 11 | g11648.t7 | ProSiteProfiles | PS51421 | small GTPase Ras family profile. | 1 | 124 | 27.3810000 |
| 7 | g11648.t7 | SMART | SM00173 | ras_sub_4 | 1 | 101 | 0.0000000 |
| 8 | g11648.t7 | SMART | SM00175 | rab_sub_5 | 1 | 100 | 0.0000001 |
| 9 | g11648.t7 | SMART | SM00174 | rho_sub_3 | 3 | 101 | 0.0092000 |
| 6 | g11648.t7 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 1 | 104 | 0.0000000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0007165 | signal transduction | BP |
| GO:0005525 | GTP binding | MF |
| GO:0003924 | GTPase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
