General information for g11673.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Importin-9.
Parent gene
- The parent gene g11673 is located on chr_1: 17738937..17742226 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11673 | g11673.t1 | isoform | g11673.t1 | 17737561 | 17740929 |
| chr_1 | g11673 | g11673.t1 | exon | g11673.t1.exon1 | 17737561 | 17737748 |
| chr_1 | g11673 | g11673.t1 | cds | g11673.t1.CDS1 | 17737561 | 17737748 |
| chr_1 | g11673 | g11673.t1 | exon | g11673.t1.exon2 | 17737814 | 17738245 |
| chr_1 | g11673 | g11673.t1 | cds | g11673.t1.CDS2 | 17737814 | 17738245 |
| chr_1 | g11673 | g11673.t1 | exon | g11673.t1.exon3 | 17738312 | 17738534 |
| chr_1 | g11673 | g11673.t1 | cds | g11673.t1.CDS3 | 17738312 | 17738534 |
| chr_1 | g11673 | g11673.t1 | exon | g11673.t1.exon4 | 17738608 | 17740571 |
| chr_1 | g11673 | g11673.t1 | cds | g11673.t1.CDS4 | 17738608 | 17740571 |
| chr_1 | g11673 | g11673.t1 | exon | g11673.t1.exon5 | 17740648 | 17740758 |
| chr_1 | g11673 | g11673.t1 | cds | g11673.t1.CDS5 | 17740648 | 17740758 |
| chr_1 | g11673 | g11673.t1 | exon | g11673.t1.exon6 | 17740821 | 17740929 |
| chr_1 | g11673 | g11673.t1 | cds | g11673.t1.CDS6 | 17740821 | 17740929 |
| chr_1 | g11673 | g11673.t1 | TSS | g11673.t1 | NA | NA |
| chr_1 | g11673 | g11673.t1 | TTS | g11673.t1 | NA | NA |
Sequences
>g11673.t1 Gene=g11673 Length=3027
ATGATGGGAGACGCTGTTAAGCAAGCAATTTTTGAGGAACTCAATATTGTTTTGAAAGAT
CCTACACAGAAAAATGAAGAACGTTTAAATCAGCTAAAATTCACAGAAAATTATGGAATT
TATCTTGCGGAATTGACGCTTGATGATTCATTAGATTCAGGATTGCGTCAACTTGCGTCT
GTCATGTTAAAGAAATATGTTGATGAGCATTGGTCACCAGATCCAAACAAAGAAGACCAA
ACACAACTTTTGGCTAGCGATGCAGTTAAACAGGCTATTAAATCAATTTTACCGAATGGT
TTATATTGCAATAATTCAAAAATTCGTAATACAGTAGCGTATACTATAAGCACAATTGCG
GGATTGGATGACTGGATCGAACTTTTTCTTATTATTGTCAATTGTCTAGCAGGAAATGAA
GATGCTGTTCATGGAGCTATGCAAGTTTTGATTGAATTTACATATGAACTTGAAGAGAAA
GTAAAGCAAGTAGGGCCAATAATTCTCTCAGAAATTTATCGTATTTACAATTCCGAAACG
CAATATAGTGTCAAAACAAGATCGTCGGCTGTTGAAATTCTCAATTCAATATTAAAGTGT
GCCAACATTCATATCGATTCAAAGGAACAAATCAGCTTCTTCGATCCGATTCTTCCTGCG
TTTTTGGAAAAATTGATTGCTGGCTTACATACACCAAACGGTAACACAAGCAACTTTAAT
TTAAAAACGGAGATTTTGCGGATTTTTACTTATATGATTTCTGAAATGCCCAAGTTTATT
CAACCTTTTATTCAAACACTTCTTCCACCTATTTGGTCACTGCTCACACAAATGGCTGAT
TTTTATATTAAAGCAATAGTCAATGAAGATGAAGGCAGTTTTGATTCATTCAACGTAGAT
GAAGATGAAAAGAATAATTTCATTAAAATGATTCTTCAAGTTTTTGAATTGATTAATGCG
ATTGCTGAAAGTAAAAAATTCAAAATGACTATCAAAAATGTGTTGAAAGATCTCGTTTAT
GTACTTATTCTTTATATGCAAATAACTGACGAACAAATTGAAGTTTGGTCAGAAGATATT
GAAAAATTTATTGAAGATGAAGATGATCCGGGAGTCGATAGTATTCGTTCATCAGGAAAA
GATATTTTAATGAGACTTGGAGAAGAATTTGAAAAAGATTTCATCGTTGGTTTTACCAAT
GCAATAAGAAAACACTTGGAAATATCTGATGTTGAACGAAACAATGGAAGAAAATCCTAT
TGGAAATCACAAGAAGCTGCAATGCTTGTTTTTGGCATTTCTGAATTTAAAGATTTAATC
ATTCGTTCACCTGAGCAATTTAATCTTGGTGATTATTTAAATATGACAAAAATGTTTATG
AGTTATCCAGTTTCTCCATTTCTCCTTGGTCGATGCTTATATGTGCTATCAAAATTCGTT
GAGACTGATCAAGGCATTATTCATTTAAATGATATCATGAACACAACATTATCAACTTTC
GAAAGCGACAAATCAATGATTTTAAAAGTATACGGCGTTCGATCGTCATATGAAATTTGT
TCAAATCTTAGCAATGCTACAGATGACCAGAAGCAGTTTGTCATCAGTAAATTGAATGTT
TTACTAGATGGAATATTACAGCTTATTCCCATTTCACAATGCGAATTATTGGGAATTACT
CTCGAATCACTTAGCGAATTACTTTCATTTGACGCCAATTTCACCGCGCAAACAGTATCT
CGTGTCATACCTTTGGTTCAAGCTTTATTTCTTAAATACCATGATGATCGCTTGTTAATT
GAGCACATTCTTGATATAGTGAAAATATGGGCACAGAATCCTAATTGCTCTATTTCTTTA
CAAGACAAAATAGTTCCGACAATGATTAAAATTTTAAATCTTGAAACTGAAAACACTAAC
GCACCAACACAAGATATTGCCTTAGATGTCTTAGAAACTATCGTCAAATACTCCAGAGCT
CCATTGAGTCCACTTTTGATTGAGCAAGCATTTCCCGCCGTTGTAAATGCAATTTTAAGA
ACTGAAGATAATTCAGTTTTACAATCGGGTGGAGAGTGTCTTCGAGCATTTTTGTTTGTG
TCAGCTGAACAAGTTTGTACATTTCAAAATGGCATGGGTCTTTCTTCGATTTTGGAAGTC
TTGACAATTTTGCTTAATCCTAAGTCGACTGAATCAAGTGCAACATTTGTTGGTCGTCTT
GTTATTACACTTATCACCAAAGCTGGAAATTTATTAGGAGATAAGATTGATTTGCTATTG
AAAGCTGCTTTAAGTAAAATGCAACTCGTTGTTTCGCTTCATGTTAATATGTCTCTTATA
ATGATTTTTGCACATTTATTTCTTATTCAAATTGATGCGGTTATGAATTTTCTTAGTTGC
ATTCCTGGACCGACAGGCGAGCCTGCAATCAATTTCGTATTTTCTAATTGGTTAACTCGT
CAGCATTCTTTTTATGGAACTTATGAGCGAAAAGTAAGCGTTATGGCATTATGCAAAATT
TTTTTGCATGGAATAAACACTCAAGATCAACGTTTAGTGAATGTTATGGTGAAAGATTTA
GTTGAATTACCAAATGCAGCACCAGTAACAACTAATGTTCGTACACGATCACAAGCAGCA
CAAACACAAGTTGTAAATGTTCCAATAATGGTCAAAATTTTTAAATTACTTATTAATGAA
TTAGTTAATTTGAGAGAAATTAAAAGCGCACTTAATAACACCATTGATAGCGAAGAGGAC
GATGACACTGAAAATAGCTTAAATACTGGATTAGAAATTGGTGAAAAAAATTTCAATGCA
TTTATGCTTTATGATGATGATGAAACTACCGAGGATGATCAAATGCTGCAAGATTTGATG
CAAGATCCTATTTTTCAAGAAGATACAGAAGTTTCGCTCACTAAATTTCTAACAGATTTT
AGTCGAAGTGAAAATTATCCAGTATTTGTGGAACAATTGACTCCTACAGAAAAGAAGCTC
TTACAAAGTTTAAACATCACAACTTAA
>g11673.t1 Gene=g11673 Length=1008
MMGDAVKQAIFEELNIVLKDPTQKNEERLNQLKFTENYGIYLAELTLDDSLDSGLRQLAS
VMLKKYVDEHWSPDPNKEDQTQLLASDAVKQAIKSILPNGLYCNNSKIRNTVAYTISTIA
GLDDWIELFLIIVNCLAGNEDAVHGAMQVLIEFTYELEEKVKQVGPIILSEIYRIYNSET
QYSVKTRSSAVEILNSILKCANIHIDSKEQISFFDPILPAFLEKLIAGLHTPNGNTSNFN
LKTEILRIFTYMISEMPKFIQPFIQTLLPPIWSLLTQMADFYIKAIVNEDEGSFDSFNVD
EDEKNNFIKMILQVFELINAIAESKKFKMTIKNVLKDLVYVLILYMQITDEQIEVWSEDI
EKFIEDEDDPGVDSIRSSGKDILMRLGEEFEKDFIVGFTNAIRKHLEISDVERNNGRKSY
WKSQEAAMLVFGISEFKDLIIRSPEQFNLGDYLNMTKMFMSYPVSPFLLGRCLYVLSKFV
ETDQGIIHLNDIMNTTLSTFESDKSMILKVYGVRSSYEICSNLSNATDDQKQFVISKLNV
LLDGILQLIPISQCELLGITLESLSELLSFDANFTAQTVSRVIPLVQALFLKYHDDRLLI
EHILDIVKIWAQNPNCSISLQDKIVPTMIKILNLETENTNAPTQDIALDVLETIVKYSRA
PLSPLLIEQAFPAVVNAILRTEDNSVLQSGGECLRAFLFVSAEQVCTFQNGMGLSSILEV
LTILLNPKSTESSATFVGRLVITLITKAGNLLGDKIDLLLKAALSKMQLVVSLHVNMSLI
MIFAHLFLIQIDAVMNFLSCIPGPTGEPAINFVFSNWLTRQHSFYGTYERKVSVMALCKI
FLHGINTQDQRLVNVMVKDLVELPNAAPVTTNVRTRSQAAQTQVVNVPIMVKIFKLLINE
LVNLREIKSALNNTIDSEEDDDTENSLNTGLEIGEKNFNAFMLYDDDETTEDDQMLQDLM
QDPIFQEDTEVSLTKFLTDFSRSENYPVFVEQLTPTEKKLLQSLNITT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g11673.t1 | Coils | Coil | Coil | 901 | 921 | - |
| 5 | g11673.t1 | Gene3D | G3DSA:1.25.10.10 | - | 20 | 978 | 4.4E-108 |
| 2 | g11673.t1 | PANTHER | PTHR10997 | IMPORTIN-7, 8, 11 | 5 | 1003 | 2.7E-157 |
| 3 | g11673.t1 | PANTHER | PTHR10997:SF9 | IMPORTIN-9 | 5 | 1003 | 2.7E-157 |
| 1 | g11673.t1 | Pfam | PF03810 | Importin-beta N-terminal domain | 26 | 101 | 3.9E-10 |
| 8 | g11673.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 768 | - |
| 9 | g11673.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 769 | 789 | - |
| 7 | g11673.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 790 | 1008 | - |
| 11 | g11673.t1 | ProSiteProfiles | PS50166 | Importin-beta N-terminal domain profile. | 25 | 103 | 12.562 |
| 10 | g11673.t1 | SMART | SM00913 | IBN_N_2 | 25 | 103 | 5.6E-6 |
| 4 | g11673.t1 | SUPERFAMILY | SSF48371 | ARM repeat | 25 | 1004 | 1.3E-86 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0031267 | small GTPase binding | MF |
| GO:0006886 | intracellular protein transport | BP |
KEGG
Orthology
- This transcript has been annotated with K20224 (importin-9)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
