General information for g11678.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as SUMO-activating enzyme subunit 1.
Parent gene
- The parent gene g11678 is located on chr_1: 17763068..17763651 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11678 | g11678.t1 | TSS | g11678.t1 | 17761943 | 17761943 |
| chr_1 | g11678 | g11678.t1 | isoform | g11678.t1 | 17762013 | 17763068 |
| chr_1 | g11678 | g11678.t1 | exon | g11678.t1.exon1 | 17762013 | 17762104 |
| chr_1 | g11678 | g11678.t1 | cds | g11678.t1.CDS1 | 17762013 | 17762104 |
| chr_1 | g11678 | g11678.t1 | exon | g11678.t1.exon2 | 17762165 | 17763068 |
| chr_1 | g11678 | g11678.t1 | cds | g11678.t1.CDS2 | 17762165 | 17763068 |
| chr_1 | g11678 | g11678.t1 | TTS | g11678.t1 | 17763167 | 17763167 |
Sequences
>g11678.t1 Gene=g11678 Length=996
ATGGTTGAACAAGACTATCAAGAACTCACTGCAGAAGAAGCCGAATTGTACGATCGTCAA
ATTCGTCTTTGGGGTTTAGAAAATCAGAAAAAATTGCGAAATTCAAAAATCTTAATTGCC
GGCATAAATGGATTGGGAGCAGAAATTGCTAAAAATATTATTTTAGCTGGAGTAAAATCC
GTGACTTTTTTGGATTCTAAATCTGTTTCAAAATTGGATTTTGCATCACAATTTTTCATT
CCACGAACTGACGAAAACAAGTTGAGAGCTGAAGCTAGTTTACCTAGAGCACAAGCACTT
AATCCTATGGTAGAACTTACAGCAGATACTGGAAATTTGCATGAAAAAGATGAGGAATTT
TTCAAAAAATTTGATGTCATTGTGATTATTGAAGGAAAAATGAGTGAACAAATTCGAATC
GATAATATCTGCAGAGCGAATAACATTAAATTTTTCGCTGCCGACATGTGGGGCTTATTT
GGATTTAGTTTTTCTGATCTTCAAGAACATGAATTTGCAGAAGACATTATCAAACATAAA
GTAGTTTCTAAACCTAATGAAAAGGTCAAAACCGAACCTATTAAAACTACATCCAAGCGC
TCTCTTAATTTTCCATCATTAGAAACAGCAATTGCTTTCGACTATAATTCACCTGCATTT
GTAAAGCGTATGAAAAAATCTGGACCTGCTCCGCTCGTAATGAAAATTCTTCAAACTTTT
CGTGAACAAGAAAATCGTGATCCACTTCCTGAAAATCGAGAAGAAGACATTAAAAAATTA
CTTTCAATTCGAGATTCATTGTCAAATTCTGAGCAAGTTACAGATATTTATTTTGAGCAT
GTCTTTGGACAAATCTCACCAAGTGCCGCAATATTAGGTGGCTCAGTTGCTCAAGAAATA
ATTAAGACAGTATCACAAAAGGATGCACCACATTACAACTATTTCTTTTTTGATCCTCAA
ACAGCATGTGGTTACATTGAGGCAATTGGAGTTTAA
>g11678.t1 Gene=g11678 Length=331
MVEQDYQELTAEEAELYDRQIRLWGLENQKKLRNSKILIAGINGLGAEIAKNIILAGVKS
VTFLDSKSVSKLDFASQFFIPRTDENKLRAEASLPRAQALNPMVELTADTGNLHEKDEEF
FKKFDVIVIIEGKMSEQIRIDNICRANNIKFFAADMWGLFGFSFSDLQEHEFAEDIIKHK
VVSKPNEKVKTEPIKTTSKRSLNFPSLETAIAFDYNSPAFVKRMKKSGPAPLVMKILQTF
REQENRDPLPENREEDIKKLLSIRDSLSNSEQVTDIYFEHVFGQISPSAAILGGSVAQEI
IKTVSQKDAPHYNYFFFDPQTACGYIEAIGV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g11678.t1 | CDD | cd01492 | Aos1_SUMO | 14 | 327 | 0 |
| 7 | g11678.t1 | Gene3D | G3DSA:3.40.50.720 | - | 2 | 331 | 0 |
| 2 | g11678.t1 | PANTHER | PTHR10953 | UBIQUITIN-ACTIVATING ENZYME E1 | 9 | 329 | 0 |
| 3 | g11678.t1 | PANTHER | PTHR10953:SF162 | SUMO-ACTIVATING ENZYME SUBUNIT 1 | 9 | 329 | 0 |
| 4 | g11678.t1 | PRINTS | PR01849 | Ubiquitin-activating enzyme E1 signature | 38 | 62 | 0 |
| 5 | g11678.t1 | PRINTS | PR01849 | Ubiquitin-activating enzyme E1 signature | 154 | 181 | 0 |
| 1 | g11678.t1 | Pfam | PF00899 | ThiF family | 17 | 318 | 0 |
| 6 | g11678.t1 | SUPERFAMILY | SSF69572 | Activating enzymes of the ubiquitin-like proteins | 10 | 327 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008641 | ubiquitin-like modifier activating enzyme activity | MF |
| GO:0006464 | cellular protein modification process | BP |
KEGG
Orthology
- This transcript has been annotated with K10684 (ubiquitin-like 1-activating enzyme E1 A)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
