Gene loci information

Transcript annotation

  • This transcript has been annotated as Splicing factor 3B subunit 6.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g11679 g11679.t1 TTS g11679.t1 17763087 17763087
chr_1 g11679 g11679.t1 isoform g11679.t1 17763149 17763651
chr_1 g11679 g11679.t1 exon g11679.t1.exon1 17763149 17763357
chr_1 g11679 g11679.t1 cds g11679.t1.CDS1 17763149 17763357
chr_1 g11679 g11679.t1 exon g11679.t1.exon2 17763419 17763560
chr_1 g11679 g11679.t1 cds g11679.t1.CDS2 17763419 17763560
chr_1 g11679 g11679.t1 exon g11679.t1.exon3 17763622 17763651
chr_1 g11679 g11679.t1 cds g11679.t1.CDS3 17763622 17763651
chr_1 g11679 g11679.t1 TSS g11679.t1 17763786 17763786

Sequences

>g11679.t1 Gene=g11679 Length=381
ATGGCGTTGGCGATGCAAAAGCGGAATAATGTTCGACTTCCTCCAGAAGTTAATAGAATA
TTATATGTAAGAAACCTTCCCTATAAAATCACTAGTGATGAAATGTATGATATTTTTGGT
AAATATGGTGCAATCAGACAAATTAGAGTTGGAAATATTCCAGAAACAAAAGGAACGGCT
TTTGTGGTATATGAAGATATTTGGGATGCAAAAAATGCATGTGATCATTTGTCTGGTTTT
AATGTCTGCAATCGCTATCTCATTGTATTATATTATCAAGCATCGAAAGCATTCAAAACT
ACTGACATAAATGCAAAACAAGATGAAATTGAAAAAATGAAGGCAAAATACAACATAAAT
TCCGATGATTTACGAAAGTGA

>g11679.t1 Gene=g11679 Length=126
MALAMQKRNNVRLPPEVNRILYVRNLPYKITSDEMYDIFGKYGAIRQIRVGNIPETKGTA
FVVYEDIWDAKNACDHLSGFNVCNRYLIVLYYQASKAFKTTDINAKQDEIEKMKAKYNIN
SDDLRK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g11679.t1 CDD cd12241 RRM_SF3B14 17 93 0.000
6 g11679.t1 Gene3D G3DSA:3.30.70.330 - 15 122 0.000
2 g11679.t1 PANTHER PTHR12785 SPLICING FACTOR 3B 5 116 0.000
3 g11679.t1 PANTHER PTHR12785:SF7 SPLICING FACTOR 3B SUBUNIT 6 5 116 0.000
1 g11679.t1 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 21 87 0.000
7 g11679.t1 ProSiteProfiles PS50102 Eukaryotic RNA Recognition Motif (RRM) profile. 19 94 14.778
5 g11679.t1 SMART SM00360 rrm1_1 20 90 0.000
4 g11679.t1 SUPERFAMILY SSF54928 RNA-binding domain, RBD 18 96 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0003676 nucleic acid binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values