General information for g1171.t11
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Thioredoxin-dependent peroxide reductase, mitochondrial.
Parent gene
- The parent gene g1171 is located on chr_3: 8483531..8484305 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1171 | g1171.t11 | isoform | g1171.t11 | 8482963 | 8484305 |
| chr_3 | g1171 | g1171.t11 | exon | g1171.t11.exon1 | 8482963 | 8483476 |
| chr_3 | g1171 | g1171.t11 | TTS | g1171.t11 | 8482969 | 8482969 |
| chr_3 | g1171 | g1171.t11 | cds | g1171.t11.CDS1 | 8483391 | 8483476 |
| chr_3 | g1171 | g1171.t11 | exon | g1171.t11.exon2 | 8483531 | 8483892 |
| chr_3 | g1171 | g1171.t11 | cds | g1171.t11.CDS2 | 8483531 | 8483892 |
| chr_3 | g1171 | g1171.t11 | exon | g1171.t11.exon3 | 8483948 | 8484104 |
| chr_3 | g1171 | g1171.t11 | cds | g1171.t11.CDS3 | 8483948 | 8484104 |
| chr_3 | g1171 | g1171.t11 | exon | g1171.t11.exon4 | 8484175 | 8484205 |
| chr_3 | g1171 | g1171.t11 | cds | g1171.t11.CDS4 | 8484175 | 8484205 |
| chr_3 | g1171 | g1171.t11 | exon | g1171.t11.exon5 | 8484267 | 8484305 |
| chr_3 | g1171 | g1171.t11 | cds | g1171.t11.CDS5 | 8484267 | 8484305 |
| chr_3 | g1171 | g1171.t11 | TSS | g1171.t11 | 8484372 | 8484372 |
Sequences
>g1171.t11 Gene=g1171 Length=1103
ATGGCATTTATTAATTCTCTCATTTCACGAAGCGTAAGTATTCGTCAAATCAACACACGA
TTTGTATCAACTTCATCAAGATTATTTGTTGCTCAAGTACAAAAACCAGCGCCAGATTTT
GAAGCTGTAGCTGTTTGTGATAATGATTTCAAAACTGTTAAGCTTGCAGATTATAAAGGA
AAATCATGGCTCGTTCTGTTTTTCTATCCGCTGGATTTCATTTTTGTTTGTCCTACGGAA
ATCATAAGTTTCTCTGATCGACTTGAAGAATTCAAAAAGCTCAATTGTGAAGTTGTCGGT
GTGTCAGTAGACTCACATTTCAGTCATTTGGCTTGGAAAAATACACCAAGAAAGGAAGGT
GGAATTGGTGACATCAAATATCCTTTATTAGCAGATTTGACTAAAAAAATATCTCAAGAT
TACGGCGTTCTACTCGAAGAGGGAGGAATTGCACTAAGAGGGCTTTTTATCATCGACCCA
AATGCAATTGTAAGACAAATAACGATCAACGATTTACCAGTTGGTCGTAGTGTTGATGAA
ACATTGCGATTGATCAAAGCATTTCAATTTGTTGAAAAGCATGGTGAAGTATGTGCTGCA
AATTGGAAAGAGAATGATCCCACAATCAAGCCAGATCCAAAAGGTTCAAAGGAATATTTT
AACAAAGTTAATTAAATTGTGTTTGTTGTATCATAGTCAGCACTGGATTTTGTGAAAAGG
AAAATAAATAGGAATGATGTCTGAAAAAGAAGTACTCAAAATTTTTAATTTGCATAATTA
TAAGCTCATTAGAGATGTGAATGAATTAAAATTACTTGTAGCAAAATTACATTCAAATCA
TCAACTTATAAGGAAATATTTTAATACACTTCGTTCAAAAGCACTAGAAAATAAAAGAAT
TCAAGAACTTTGTTATCGTGTTCGATCTAAAGAAATTACATTATCACAAAGTCTCAGCAT
ATCATGCCTCAAACCGTCACTGATCAAGCTTATATTTGCATTAAATCATTATCGAATCAA
ACTCATGCAAAGAATATTCAATAAATTCAAAACTTTTCATTTATTTCGTTAATAAAAACA
CAAAATTATCAAACTATAAATTA
>g1171.t11 Gene=g1171 Length=224
MAFINSLISRSVSIRQINTRFVSTSSRLFVAQVQKPAPDFEAVAVCDNDFKTVKLADYKG
KSWLVLFFYPLDFIFVCPTEIISFSDRLEEFKKLNCEVVGVSVDSHFSHLAWKNTPRKEG
GIGDIKYPLLADLTKKISQDYGVLLEEGGIALRGLFIIDPNAIVRQITINDLPVGRSVDE
TLRLIKAFQFVEKHGEVCAANWKENDPTIKPDPKGSKEYFNKVN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g1171.t11 | CDD | cd03015 | PRX_Typ2cys | 33 | 204 | 0.000 |
| 6 | g1171.t11 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 28 | 224 | 0.000 |
| 3 | g1171.t11 | PANTHER | PTHR10681 | THIOREDOXIN PEROXIDASE | 16 | 223 | 0.000 |
| 4 | g1171.t11 | PANTHER | PTHR10681:SF142 | PEROXIREDOXIN 3 | 16 | 223 | 0.000 |
| 8 | g1171.t11 | PIRSF | PIRSF000239 | AHPC | 27 | 224 | 0.000 |
| 2 | g1171.t11 | Pfam | PF00578 | AhpC/TSA family | 33 | 166 | 0.000 |
| 1 | g1171.t11 | Pfam | PF10417 | C-terminal domain of 1-Cys peroxiredoxin | 187 | 222 | 0.000 |
| 7 | g1171.t11 | ProSiteProfiles | PS51352 | Thioredoxin domain profile. | 31 | 190 | 17.975 |
| 5 | g1171.t11 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 32 | 223 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016209 | antioxidant activity | MF |
| GO:0055114 | NA | NA |
| GO:0051920 | peroxiredoxin activity | MF |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K03386 (peroxiredoxin 2/4)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed