General information for g11711.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Eye-specific diacylglycerol kinase.
Parent gene
- The parent gene g11711 is located on chr_1: 17988715..17998172 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11711 | g11711.t3 | isoform | g11711.t3 | 17972191 | 17992918 |
| chr_1 | g11711 | g11711.t3 | exon | g11711.t3.exon1 | 17972191 | 17972460 |
| chr_1 | g11711 | g11711.t3 | TSS | g11711.t3 | 17972194 | 17972194 |
| chr_1 | g11711 | g11711.t3 | exon | g11711.t3.exon2 | 17989084 | 17989222 |
| chr_1 | g11711 | g11711.t3 | exon | g11711.t3.exon3 | 17989895 | 17990098 |
| chr_1 | g11711 | g11711.t3 | cds | g11711.t3.CDS1 | 17989910 | 17990098 |
| chr_1 | g11711 | g11711.t3 | exon | g11711.t3.exon4 | 17992414 | 17992543 |
| chr_1 | g11711 | g11711.t3 | cds | g11711.t3.CDS2 | 17992414 | 17992543 |
| chr_1 | g11711 | g11711.t3 | exon | g11711.t3.exon5 | 17992618 | 17992918 |
| chr_1 | g11711 | g11711.t3 | cds | g11711.t3.CDS3 | 17992618 | 17992916 |
| chr_1 | g11711 | g11711.t3 | TTS | g11711.t3 | NA | NA |
Sequences
>g11711.t3 Gene=g11711 Length=1044
GTTTAGTTGTTTTTCACTCGTCGTTATTCAAAGACCGTACATGTTTTAATGAAACTTAAA
AATTGTTTTTCATCATTTTTATTAAGTAATTACTTCAATAATTACTATTTTTAATTTTTA
TCGAGAATTGCTAAAAATATTCTTCCATTCCATGACTGAAAATATTTTGAACGGAAACAT
ATAGTCATTAGTTTATATTGTTTGAAAACATTCGCGAGATGAAGTGGATATTAAAAAGTT
CTGGAATAATTTACATAAATGATAGTGTAAAAAACCAGGCGATAATTCAGGAACACGACA
AATAAGAAACACACCGGACTGGACAGAAAATGCTGTGTCAGGAGATCATTTGTGGGTGCC
TACTTCGGTATCAGGAGATTGCTGTTATATCGGTGATAATGACTGTACTAAACATGGACC
AAGAATGAAATGTTCCGCATGTAAAATTATTGCTCATGCAAGTTGTATATCGATTTTAAT
GGATCGATCGCAATTAGCATGCAAACCAACATTTCGTGATGTGGGTGTCCGTCAATATCG
AGAACAAACTAGAACTCATCATCATTGGATACATCGCCGTACTGAGAAAGGCAAATGTCG
TCAGTGTGGAAAGTCTTTACAAGCGAAATTATCATTTAGTTCAAAGGAGATTGTGGCTTT
ATCATGTGCCTGGTGCAAATCATCATATCATAATAAAGAGGCATGTTTTAATCCACAGCG
CATAGGTGAAGAGTGTTCATTAGGGACTCATTCACGTATAATAGTTCCTCCATCATGGAT
TGTAAAACTTCCAAAAAGAGGCAGTTTCAAATCATCACTGCGGAAAACACCAAAAAAGAA
AACAGCCGGAAAGAAAAAGTCTAAAGAGAAAGAGCTGAGAACATTTGTAATAAAACCTAT
TCCAACACCAAATCTTACGCCTGTTTTGGTTTTTATAAATCCAAAAAGTGGCGGTAATCA
AGGTGCAAAATTACTTCAAAAATTCCAATGGCTTCTGAATCCTCGTCAAGTATTTGATTT
GACACAAGGTGGACCTAAAATGGG
>g11711.t3 Gene=g11711 Length=206
MKCSACKIIAHASCISILMDRSQLACKPTFRDVGVRQYREQTRTHHHWIHRRTEKGKCRQ
CGKSLQAKLSFSSKEIVALSCAWCKSSYHNKEACFNPQRIGEECSLGTHSRIIVPPSWIV
KLPKRGSFKSSLRKTPKKKTAGKKKSKEKELRTFVIKPIPTPNLTPVLVFINPKSGGNQG
AKLLQKFQWLLNPRQVFDLTQGGPKM
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g11711.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 129 | 145 | - |
| 6 | g11711.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 129 | 148 | - |
| 3 | g11711.t3 | PANTHER | PTHR11255:SF43 | DIACYLGLYCEROL KINASE ZETA | 2 | 205 | 4.8E-83 |
| 4 | g11711.t3 | PANTHER | PTHR11255 | DIACYLGLYCEROL KINASE | 2 | 205 | 4.8E-83 |
| 2 | g11711.t3 | Pfam | PF00130 | Phorbol esters/diacylglycerol binding domain (C1 domain) | 46 | 104 | 1.3E-10 |
| 1 | g11711.t3 | Pfam | PF00781 | Diacylglycerol kinase catalytic domain | 166 | 201 | 2.7E-6 |
| 8 | g11711.t3 | ProSiteProfiles | PS50146 | DAG-kinase catalytic (DAGKc) domain profile. | 162 | 206 | 17.647 |
| 7 | g11711.t3 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 24 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004143 | diacylglycerol kinase activity | MF |
| GO:0007165 | signal transduction | BP |
| GO:0016301 | kinase activity | MF |
| GO:0035556 | intracellular signal transduction | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
