General information for g11758.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Solute carrier family 26 member 6.
Parent gene
- The parent gene g11758 is located on chr_1: 18259412..18261912 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11758 | g11758.t1 | TTS | g11758.t1 | 18258487 | 18258487 |
| chr_1 | g11758 | g11758.t1 | isoform | g11758.t1 | 18259412 | 18261912 |
| chr_1 | g11758 | g11758.t1 | exon | g11758.t1.exon1 | 18259412 | 18260266 |
| chr_1 | g11758 | g11758.t1 | cds | g11758.t1.CDS1 | 18259412 | 18260266 |
| chr_1 | g11758 | g11758.t1 | exon | g11758.t1.exon2 | 18260321 | 18260728 |
| chr_1 | g11758 | g11758.t1 | cds | g11758.t1.CDS2 | 18260321 | 18260728 |
| chr_1 | g11758 | g11758.t1 | exon | g11758.t1.exon3 | 18260820 | 18260984 |
| chr_1 | g11758 | g11758.t1 | cds | g11758.t1.CDS3 | 18260820 | 18260984 |
| chr_1 | g11758 | g11758.t1 | exon | g11758.t1.exon4 | 18261053 | 18261468 |
| chr_1 | g11758 | g11758.t1 | cds | g11758.t1.CDS4 | 18261053 | 18261468 |
| chr_1 | g11758 | g11758.t1 | exon | g11758.t1.exon5 | 18261729 | 18261912 |
| chr_1 | g11758 | g11758.t1 | cds | g11758.t1.CDS5 | 18261729 | 18261912 |
| chr_1 | g11758 | g11758.t1 | TSS | g11758.t1 | 18262444 | 18262444 |
Sequences
>g11758.t1 Gene=g11758 Length=2028
ATGTTTCGGGATCAAAATGAAGACAAGAATGGTTTTTTTAATGAAGGACTTGATGTTTGT
AGTGATGAAAGCAATTTACAAAAATTCGACTGTGATAATACGAAAATTGAAATTATCCGA
TTGAAATATAATCAAGAATCACTTTTTCGAGAAATGGCTTACAGGAAGCCGTCATCAAAG
TCATTTATTGCTAAGAAATTCAATAATGTGAACAAAAAAGCAATACGAACATGTGCTATT
GAAAGCTTTCCTATTATTACATGGCTTTATTCGTACAAAAAGGATGATTTCGCTAGTGAC
TTGATAAGTGGATGCACAGTTGCTATTATGCAAATACCTCAAGGCATGGGTTACTCTTTA
CTTGCGAATCTTCCTCCTATTGTCGGAATTTATATGGCATTCTTTCCTGTGCTAATATAT
GCACTTTTTGGAACTTCGAAACATAACAGTATGGGAACATTCGCTGTAATTTCAATTATG
GTAGGAAAATGTATTACAACATATTCCTATCAATATTCGGATTCATCTATAGCAAAACAA
GCTGCTTATTCACCTATTGAAGTCGCTACTCTTCTTTGCTTTTTAGTAGGAACAATGCAG
TTAATCATGTGGCTGTTACGATTGGGAATTATGTCATTTTTGCTCTCAGAAAGTTTAGTT
TCTGGATTTACAACTGGAGCAGCAATTCATGTTCTTACAAGTCAAGTGAAAGATCTATTG
GGAATTGAATTACCAGGGATTAATGGCAACTTCAAACTTGTAAAGACATATGTTGAAATT
TTTAGTCAAGTAAACAGCAACCGCTTTAATGTAACATCGATAATCTTATCAACTCTAACA
ATCTTGCTACTTTTGCTCAATAATGAAATATTAAAACCAATTTTGGCAAGAAAAACAAAA
ATTCCAATTCCTATTGAGCTTTTTGTGGTTGTTGGTGGTACGTTATTTTCAAAATATATC
AGACTTTATGAAAACTTCAACGTAATACTTATTGGCCATATTCCACTTGGATTTCCTAGC
ATGACAATCTGTAGATTTGATTTATGGAAAGAACTCTTATTAGATTCTATTGCAATTAGC
ATAGTCAGCTATTCTATTACTGTTTCCATGGCTTTGATTTTGGGACAAAAGTTGAAATAT
GAAATTAACTTCAACCAAGAATTACTTGCAATGGGTTTAGGAAACATTTTTGGATCATTT
TTTTCATGTTTTCCTTATTCGGCATCTTTATCAAGATCACTTATTCAACAAAATGTTGGA
GGGAAGACACAACTTGCATCACTGATTTCATGTGTATTACTTTTCTTTGTACTTATGTGG
ATTGGACCATTTTTTGAAGATCTTCCTCGTTGTATTTTGGCTTCAATAATAGTTATAGCA
ATTAAAGGCATGGTCATGCAAGTCAAAGACTTTAAAAATTTTAAAAGAAAGAGTAACAGT
GATGCTCTTGTATGGATGTGCACATTTTTAGCAGTAATTTTTTTATCAATAGACATTGGA
TTGCTTATCGGTATATGTTTAAGCATTTTGTGTATTTTTTGTAATGGTTTGAAATGTTAT
GTTTGCGTTTTGGGAAATGTTCCAAACACAGATCTTTTTTTAGATATTGATAATTTTCAA
AAAGCTGTTGAAATACCTTATGTAAAAATTCTTCAGCTTTCTGGTTCTATTAATTTTGCA
ACTAAAGTCTTTTTGCGAAATCAAATCTGCAGTAAATTGAAAATTAATTTGATAAAGGAA
TTAAAAATTAAAGAACTTAATAACAATGCAGATAAGTCAAATAAGAACTTAACATCTAAT
ATAAATTTCAAGCATTTAATTCTAGATTTTGGATCATTGACTAGTATAGATGCAAGTTCA
ATTGTAATGCTTTCAGATTTGATAAAAGACTTGAACAAACTAGATCTGAAAGTTTCTATT
ACGTCTTGCTCTTCTTCAAGAATTTATGAGGTTCTATTAAAAAATGAATTTGAATTTATG
CACATAATGTATCCTTCTATACAAGATGTAGAAGTCGGAATTTTGTGA
>g11758.t1 Gene=g11758 Length=675
MFRDQNEDKNGFFNEGLDVCSDESNLQKFDCDNTKIEIIRLKYNQESLFREMAYRKPSSK
SFIAKKFNNVNKKAIRTCAIESFPIITWLYSYKKDDFASDLISGCTVAIMQIPQGMGYSL
LANLPPIVGIYMAFFPVLIYALFGTSKHNSMGTFAVISIMVGKCITTYSYQYSDSSIAKQ
AAYSPIEVATLLCFLVGTMQLIMWLLRLGIMSFLLSESLVSGFTTGAAIHVLTSQVKDLL
GIELPGINGNFKLVKTYVEIFSQVNSNRFNVTSIILSTLTILLLLLNNEILKPILARKTK
IPIPIELFVVVGGTLFSKYIRLYENFNVILIGHIPLGFPSMTICRFDLWKELLLDSIAIS
IVSYSITVSMALILGQKLKYEINFNQELLAMGLGNIFGSFFSCFPYSASLSRSLIQQNVG
GKTQLASLISCVLLFFVLMWIGPFFEDLPRCILASIIVIAIKGMVMQVKDFKNFKRKSNS
DALVWMCTFLAVIFLSIDIGLLIGICLSILCIFCNGLKCYVCVLGNVPNTDLFLDIDNFQ
KAVEIPYVKILQLSGSINFATKVFLRNQICSKLKINLIKELKIKELNNNADKSNKNLTSN
INFKHLILDFGSLTSIDASSIVMLSDLIKDLNKLDLKVSITSCSSSRIYEVLLKNEFEFM
HIMYPSIQDVEVGIL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 30 | g11758.t1 | CDD | cd07042 | STAS_SulP_like_sulfate_transporter | 539 | 657 | 6.7677E-11 |
| 6 | g11758.t1 | Gene3D | G3DSA:3.30.750.24 | - | 520 | 672 | 3.6E-23 |
| 3 | g11758.t1 | PANTHER | PTHR11814:SF180 | ANION TRANSPORTER SULP-8A | 66 | 670 | 1.3E-193 |
| 4 | g11758.t1 | PANTHER | PTHR11814 | SULFATE TRANSPORTER | 66 | 670 | 1.3E-193 |
| 1 | g11758.t1 | Pfam | PF00916 | Sulfate permease family | 97 | 488 | 1.4E-104 |
| 2 | g11758.t1 | Pfam | PF01740 | STAS domain | 542 | 669 | 5.0E-12 |
| 12 | g11758.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 119 | - |
| 27 | g11758.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 120 | 143 | - |
| 18 | g11758.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 144 | 148 | - |
| 24 | g11758.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 149 | 170 | - |
| 9 | g11758.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 171 | 181 | - |
| 29 | g11758.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 182 | 206 | - |
| 15 | g11758.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 207 | 270 | - |
| 23 | g11758.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 271 | 291 | - |
| 8 | g11758.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 292 | 302 | - |
| 25 | g11758.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 303 | 320 | - |
| 14 | g11758.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 321 | 325 | - |
| 20 | g11758.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 326 | 344 | - |
| 11 | g11758.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 345 | 355 | - |
| 21 | g11758.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 356 | 376 | - |
| 17 | g11758.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 377 | 387 | - |
| 19 | g11758.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 388 | 404 | - |
| 7 | g11758.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 405 | 424 | - |
| 26 | g11758.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 425 | 445 | - |
| 13 | g11758.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 446 | 450 | - |
| 28 | g11758.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 451 | 471 | - |
| 10 | g11758.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 472 | 482 | - |
| 22 | g11758.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 483 | 510 | - |
| 16 | g11758.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 511 | 675 | - |
| 41 | g11758.t1 | ProSiteProfiles | PS50801 | STAS domain profile. | 538 | 652 | 15.385 |
| 5 | g11758.t1 | SUPERFAMILY | SSF52091 | SpoIIaa-like | 544 | 651 | 9.81E-10 |
| 42 | g11758.t1 | TIGRFAM | TIGR00815 | sulP: sulfate permease | 84 | 647 | 2.7E-132 |
| 36 | g11758.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 119 | 141 | - |
| 35 | g11758.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 151 | 170 | - |
| 32 | g11758.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 183 | 205 | - |
| 31 | g11758.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 269 | 291 | - |
| 33 | g11758.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 326 | 343 | - |
| 39 | g11758.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 353 | 375 | - |
| 37 | g11758.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 388 | 410 | - |
| 38 | g11758.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 425 | 444 | - |
| 40 | g11758.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 451 | 468 | - |
| 34 | g11758.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 488 | 510 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0055085 | transmembrane transport | BP |
| GO:0015116 | sulfate transmembrane transporter activity | MF |
| GO:0008272 | sulfate transport | BP |
| GO:0016021 | integral component of membrane | CC |
| GO:0008271 | secondary active sulfate transmembrane transporter activity | MF |
KEGG
Orthology
- This transcript has been annotated with K14078 (solute carrier family 26 (chloride anion exchanger), member 3)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
