General information for g11785.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as G-protein coupled receptor moody.
Parent gene
- The parent gene g11785 is located on chr_1: 18405344..18407448 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11785 | g11785.t1 | isoform | g11785.t1 | 18400852 | 18405455 |
| chr_1 | g11785 | g11785.t1 | exon | g11785.t1.exon1 | 18400852 | 18400943 |
| chr_1 | g11785 | g11785.t1 | cds | g11785.t1.CDS1 | 18400852 | 18400943 |
| chr_1 | g11785 | g11785.t1 | exon | g11785.t1.exon2 | 18401003 | 18401334 |
| chr_1 | g11785 | g11785.t1 | cds | g11785.t1.CDS2 | 18401003 | 18401334 |
| chr_1 | g11785 | g11785.t1 | exon | g11785.t1.exon3 | 18401400 | 18401491 |
| chr_1 | g11785 | g11785.t1 | cds | g11785.t1.CDS3 | 18401400 | 18401491 |
| chr_1 | g11785 | g11785.t1 | exon | g11785.t1.exon4 | 18401559 | 18402172 |
| chr_1 | g11785 | g11785.t1 | cds | g11785.t1.CDS4 | 18401559 | 18402172 |
| chr_1 | g11785 | g11785.t1 | exon | g11785.t1.exon5 | 18402236 | 18402441 |
| chr_1 | g11785 | g11785.t1 | cds | g11785.t1.CDS5 | 18402236 | 18402441 |
| chr_1 | g11785 | g11785.t1 | exon | g11785.t1.exon6 | 18402810 | 18402933 |
| chr_1 | g11785 | g11785.t1 | cds | g11785.t1.CDS6 | 18402810 | 18402933 |
| chr_1 | g11785 | g11785.t1 | exon | g11785.t1.exon7 | 18403166 | 18403240 |
| chr_1 | g11785 | g11785.t1 | cds | g11785.t1.CDS7 | 18403166 | 18403240 |
| chr_1 | g11785 | g11785.t1 | exon | g11785.t1.exon8 | 18403321 | 18403360 |
| chr_1 | g11785 | g11785.t1 | cds | g11785.t1.CDS8 | 18403321 | 18403360 |
| chr_1 | g11785 | g11785.t1 | exon | g11785.t1.exon9 | 18405148 | 18405284 |
| chr_1 | g11785 | g11785.t1 | cds | g11785.t1.CDS9 | 18405148 | 18405284 |
| chr_1 | g11785 | g11785.t1 | exon | g11785.t1.exon10 | 18405350 | 18405455 |
| chr_1 | g11785 | g11785.t1 | cds | g11785.t1.CDS10 | 18405350 | 18405455 |
| chr_1 | g11785 | g11785.t1 | TSS | g11785.t1 | NA | NA |
| chr_1 | g11785 | g11785.t1 | TTS | g11785.t1 | NA | NA |
Sequences
>g11785.t1 Gene=g11785 Length=1818
ATGGATCTTCTACCATTTGTGCCTGATTCAAGTGAAGATGATCATATTATTACTAACTAC
AGTTTTAGTTCTTTTGGAATATCATCTGTTAGTGAATTTAAAACATCTAATCCATATGAA
AACTTGTTCAAAGGATTTTCTCCTCTTTTACTTTATTTTGCTTCAACTTGCTGTTTTCTA
TTTATGCTTCTTGGAATACCAGGAAATCTCTTCACAATTATAGCGTTAGCAAAATGTAAA
AAAGTTAGAAATGCTACAGCAGTTTTTATCATAAATTTATCATGTTCAGATTTACTATTT
TGTTGCTTTAATCTTCCACTTGCGGCTACCACATTTTACTACAGAGAATGGGTTCATGGT
GAATTAATGTGTCGTCTTTATCCATTATTACGTTATGGACTTCTAGCTGTATCTTTATTT
TCGATTTTAACAATAACAATTAATCGTTATATAATGATTGGACATCCTCGCGCTTATCCA
CGCATCTACAGACGACGTTGGTTAATACTTATGGTTTCATTGACTTGGATATGTTCGTTT
GGCACGTTGATTCAAACATGGCGAGGCAAATGGGGTAAATTTGGGATGGATACAACTATT
GGAAGTTGTAGTATACTTCCTGTTGACTCAAGATCTCCTAAAGAGTTCTTATTTGTAATG
GCCTTCATTCTTCCATGTTTTGCAATAGTTCTTTGCTATGCACGGATTTTTTATATAGTT
CGTAAAACGGCATTAAAAACACACGAAATACCAAAAGTTAATGGATCAATAAAAATGAAT
CACAATAACAATATAAACAATATAAAAAGGACACCGAGTCCAATTGAACAAAAAATTGTT
TGTAATAAAATAAATGTGAAAAGAACTTCATTTTGTGAATGCAACGATGATAATGAAGGA
ATAAAACTACCAATTAATAATGATAAGCAGCATCGTAAATGTTTAGCAAAATTAAAGAAT
GAAGATTTAAAATTTATTGATACGAGCTGCGAGAGTGATTTGCCACCGACCCTATCTCAA
TTGCAACGAAAGAGTGTTCATATTTCAAATGAGAATATCGTTTCGTCACCGCTGCTTTCA
TCGCCCACCACGACAACAACACTCGCAATTATTTCATTAGAATGTGACAATATGCACCAA
AAGCAATTAAATATAATTAATAATGAAGAAAGAGGCGACAGAGTGAACACATCACTAAAT
GTGACAACAATTCCAAAAATATCAACTTCTGGTACAACAAAAAATATACATGATATGGGT
GCGGATTCTGCTGTAGAAGATAGCACTATATCAATAGAACAACAAAATATTGCCAATCAT
TTATTATCAATTCCTGAACCATCAAGTAGTTCATCAGGAATTGAATTACCTTATGATCAA
GAATCTCCAAAAAAAAAATCAAAAAAGGCCAAAAAACCTACGAAAGTTAAACAAAAAAAC
ATAAAAGATGAGAAACCACCAACAGATGCCATCAGAAAAAAATCTTTGGCAAATACATCA
GGTGCATCAATTATATATGGTGCAGCGAGAATGTCAACTAAGGATCGAAGACTCCTTAAA
ATGATCCTTGTAATTTTCATTTCATTTCTCACGTGCTATCTACCAATAACCCTTACAAAG
ATTATGAGTTCGATAGCAAATATTAATTTCATTTTTATTACTTCGTATCTCTTAGTTTAT
TTGACAACATGCATAAACCCAATCATCTATGTTTTGATAAGCTCGGAATACCGACAAGCT
TACAAACAACTTTTTATTTGTAATGTTAAAAATTCGCGTGGTCTTGGTATTTGTAATGAA
AAGAGAAGGAAAACATAA
>g11785.t1 Gene=g11785 Length=605
MDLLPFVPDSSEDDHIITNYSFSSFGISSVSEFKTSNPYENLFKGFSPLLLYFASTCCFL
FMLLGIPGNLFTIIALAKCKKVRNATAVFIINLSCSDLLFCCFNLPLAATTFYYREWVHG
ELMCRLYPLLRYGLLAVSLFSILTITINRYIMIGHPRAYPRIYRRRWLILMVSLTWICSF
GTLIQTWRGKWGKFGMDTTIGSCSILPVDSRSPKEFLFVMAFILPCFAIVLCYARIFYIV
RKTALKTHEIPKVNGSIKMNHNNNINNIKRTPSPIEQKIVCNKINVKRTSFCECNDDNEG
IKLPINNDKQHRKCLAKLKNEDLKFIDTSCESDLPPTLSQLQRKSVHISNENIVSSPLLS
SPTTTTTLAIISLECDNMHQKQLNIINNEERGDRVNTSLNVTTIPKISTSGTTKNIHDMG
ADSAVEDSTISIEQQNIANHLLSIPEPSSSSSGIELPYDQESPKKKSKKAKKPTKVKQKN
IKDEKPPTDAIRKKSLANTSGASIIYGAARMSTKDRRLLKMILVIFISFLTCYLPITLTK
IMSSIANINFIFITSYLLVYLTTCINPIIYVLISSEYRQAYKQLFICNVKNSRGLGICNE
KRRKT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g11785.t1 | Gene3D | G3DSA:1.20.1070.10 | - | 30 | 283 | 2.5E-46 |
| 13 | g11785.t1 | Gene3D | G3DSA:1.20.1070.10 | - | 461 | 596 | 1.9E-18 |
| 39 | g11785.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 448 | 489 | - |
| 3 | g11785.t1 | PANTHER | PTHR24228:SF62 | AGAP001498-PA | 40 | 398 | 3.6E-162 |
| 5 | g11785.t1 | PANTHER | PTHR24228 | B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR | 40 | 398 | 3.6E-162 |
| 2 | g11785.t1 | PANTHER | PTHR24228:SF62 | AGAP001498-PA | 470 | 591 | 3.6E-162 |
| 4 | g11785.t1 | PANTHER | PTHR24228 | B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR | 470 | 591 | 3.6E-162 |
| 10 | g11785.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 53 | 77 | 1.7E-30 |
| 8 | g11785.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 86 | 107 | 1.7E-30 |
| 7 | g11785.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 131 | 153 | 1.7E-30 |
| 9 | g11785.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 214 | 237 | 1.7E-30 |
| 11 | g11785.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 518 | 542 | 1.7E-30 |
| 6 | g11785.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 552 | 578 | 1.7E-30 |
| 1 | g11785.t1 | Pfam | PF00001 | 7 transmembrane receptor (rhodopsin family) | 68 | 570 | 5.9E-49 |
| 19 | g11785.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 48 | - |
| 26 | g11785.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 49 | 77 | - |
| 16 | g11785.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 78 | 88 | - |
| 25 | g11785.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 89 | 109 | - |
| 22 | g11785.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 110 | 128 | - |
| 24 | g11785.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 129 | 147 | - |
| 15 | g11785.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 148 | 166 | - |
| 23 | g11785.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 167 | 187 | - |
| 21 | g11785.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 188 | 215 | - |
| 29 | g11785.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 216 | 238 | - |
| 17 | g11785.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 239 | 517 | - |
| 28 | g11785.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 518 | 536 | - |
| 20 | g11785.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 537 | 547 | - |
| 27 | g11785.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 548 | 573 | - |
| 18 | g11785.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 574 | 605 | - |
| 38 | g11785.t1 | ProSitePatterns | PS00237 | G-protein coupled receptors family 1 signature. | 137 | 153 | - |
| 40 | g11785.t1 | ProSiteProfiles | PS50262 | G-protein coupled receptors family 1 profile. | 68 | 570 | 34.936 |
| 37 | g11785.t1 | SMART | SM01381 | 7TM_GPCR_Srsx_2 | 62 | 585 | 2.1E-4 |
| 12 | g11785.t1 | SUPERFAMILY | SSF81321 | Family A G protein-coupled receptor-like | 47 | 591 | 5.22E-59 |
| 33 | g11785.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 52 | 74 | - |
| 31 | g11785.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 87 | 109 | - |
| 35 | g11785.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 129 | 151 | - |
| 30 | g11785.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 167 | 189 | - |
| 36 | g11785.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 216 | 238 | - |
| 34 | g11785.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 518 | 537 | - |
| 32 | g11785.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 552 | 574 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0007186 | G protein-coupled receptor signaling pathway | BP |
| GO:0016021 | integral component of membrane | CC |
| GO:0004930 | G protein-coupled receptor activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
