Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative 5-hydroxyisourate hydrolase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g11839 g11839.t2 TTS g11839.t2 18693268 18693268
chr_1 g11839 g11839.t2 isoform g11839.t2 18693299 18694050
chr_1 g11839 g11839.t2 exon g11839.t2.exon1 18693299 18693388
chr_1 g11839 g11839.t2 cds g11839.t2.CDS1 18693299 18693388
chr_1 g11839 g11839.t2 exon g11839.t2.exon2 18693452 18693681
chr_1 g11839 g11839.t2 cds g11839.t2.CDS2 18693452 18693681
chr_1 g11839 g11839.t2 exon g11839.t2.exon3 18693739 18693814
chr_1 g11839 g11839.t2 cds g11839.t2.CDS3 18693739 18693769
chr_1 g11839 g11839.t2 exon g11839.t2.exon4 18693953 18694050
chr_1 g11839 g11839.t2 TSS g11839.t2 NA NA

Sequences

>g11839.t2 Gene=g11839 Length=494
ACATTCATTGTGTAATCACTTAGTAGGTAGTGCAAAAAAAACGTAGAAAGCTTTGCATGT
ATTGAAAATTTTATTTATAAAATTAAAAATTGTGCTAATTCAGTAAAAAGATAATTTCAA
CTCATTCAGTTCAACTCTTCATTATGAGTAACAAACTTCCTCTTTCGACTCATGTTTTAG
ACACTACAGTTGGTCAACCAGGAAAGAATATGAAAATTAAATTATTTAAATCTAAAGACA
ATTACTGGGCAAGTTCATCAACCTCTTTTGTTACTGATGAAAATGGAAGATTCGGAGAAT
TTCTTAAAATTGATGATGAAGTGTGTGGAACATACAAACTTAAATTTGAAGTGGAAGAAT
ATTTTAAAAGTCAAGAAAAGGAATGCTTATATCCATTTGTTGAGATAGTTTTCAAAATAT
CATCGAGCAATGAACACTATCATATTCCACTAATTATAACACCTTACAGTTATTCTACTT
ATCGTGGTTCTTAA

>g11839.t2 Gene=g11839 Length=116
MSNKLPLSTHVLDTTVGQPGKNMKIKLFKSKDNYWASSSTSFVTDENGRFGEFLKIDDEV
CGTYKLKFEVEEYFKSQEKECLYPFVEIVFKISSSNEHYHIPLIITPYSYSTYRGS

Protein features from InterProScan

Transcript Database ID Name Start End E.value
9 g11839.t2 CDD cd05822 TLP_HIUase 6 116 1.08411E-51
8 g11839.t2 Gene3D G3DSA:2.60.40.180 - 1 115 5.3E-39
2 g11839.t2 PANTHER PTHR10395:SF7 5-HYDROXYISOURATE HYDROLASE 3 116 2.6E-37
3 g11839.t2 PANTHER PTHR10395 URICASE AND TRANSTHYRETIN-RELATED 3 116 2.6E-37
6 g11839.t2 PRINTS PR00189 Transthyretin signature 6 26 1.0E-11
4 g11839.t2 PRINTS PR00189 Transthyretin signature 39 64 1.0E-11
5 g11839.t2 PRINTS PR00189 Transthyretin signature 94 116 1.0E-11
1 g11839.t2 Pfam PF00576 HIUase/Transthyretin family 7 115 8.8E-35
10 g11839.t2 ProSitePatterns PS00768 Transthyretin signature 1. 10 25 -
11 g11839.t2 ProSitePatterns PS00769 Transthyretin signature 2. 99 111 -
12 g11839.t2 SMART SM00095 transthy-fin 2 115 4.6E-4
7 g11839.t2 SUPERFAMILY SSF49472 Transthyretin (synonym: prealbumin) 5 116 4.19E-38
13 g11839.t2 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 6 116 3.1E-39

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006144 purine nucleobase metabolic process BP
GO:0033971 hydroxyisourate hydrolase activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed