General information for g11861.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glucose dehydrogenase.
Parent gene
- The parent gene g11861 is located on chr_1: 18820675..18823102 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11861 | g11861.t1 | TTS | g11861.t1 | 18820451 | 18820451 |
| chr_1 | g11861 | g11861.t1 | isoform | g11861.t1 | 18820675 | 18823102 |
| chr_1 | g11861 | g11861.t1 | exon | g11861.t1.exon1 | 18820675 | 18820811 |
| chr_1 | g11861 | g11861.t1 | cds | g11861.t1.CDS1 | 18820675 | 18820811 |
| chr_1 | g11861 | g11861.t1 | exon | g11861.t1.exon2 | 18820879 | 18820926 |
| chr_1 | g11861 | g11861.t1 | cds | g11861.t1.CDS2 | 18820879 | 18820926 |
| chr_1 | g11861 | g11861.t1 | exon | g11861.t1.exon3 | 18821010 | 18821072 |
| chr_1 | g11861 | g11861.t1 | cds | g11861.t1.CDS3 | 18821010 | 18821072 |
| chr_1 | g11861 | g11861.t1 | exon | g11861.t1.exon4 | 18821166 | 18821523 |
| chr_1 | g11861 | g11861.t1 | cds | g11861.t1.CDS4 | 18821166 | 18821523 |
| chr_1 | g11861 | g11861.t1 | exon | g11861.t1.exon5 | 18821589 | 18821806 |
| chr_1 | g11861 | g11861.t1 | cds | g11861.t1.CDS5 | 18821589 | 18821806 |
| chr_1 | g11861 | g11861.t1 | exon | g11861.t1.exon6 | 18821866 | 18821928 |
| chr_1 | g11861 | g11861.t1 | cds | g11861.t1.CDS6 | 18821866 | 18821928 |
| chr_1 | g11861 | g11861.t1 | exon | g11861.t1.exon7 | 18821986 | 18822114 |
| chr_1 | g11861 | g11861.t1 | cds | g11861.t1.CDS7 | 18821986 | 18822114 |
| chr_1 | g11861 | g11861.t1 | exon | g11861.t1.exon8 | 18822180 | 18822559 |
| chr_1 | g11861 | g11861.t1 | cds | g11861.t1.CDS8 | 18822180 | 18822559 |
| chr_1 | g11861 | g11861.t1 | exon | g11861.t1.exon9 | 18822619 | 18822698 |
| chr_1 | g11861 | g11861.t1 | cds | g11861.t1.CDS9 | 18822619 | 18822698 |
| chr_1 | g11861 | g11861.t1 | exon | g11861.t1.exon10 | 18822763 | 18822963 |
| chr_1 | g11861 | g11861.t1 | cds | g11861.t1.CDS10 | 18822763 | 18822963 |
| chr_1 | g11861 | g11861.t1 | exon | g11861.t1.exon11 | 18823022 | 18823102 |
| chr_1 | g11861 | g11861.t1 | cds | g11861.t1.CDS11 | 18823022 | 18823102 |
| chr_1 | g11861 | g11861.t1 | TSS | g11861.t1 | NA | NA |
Sequences
>g11861.t1 Gene=g11861 Length=1758
ATGAATTATCTAATTTATAATTCAAGTAGCATCATTGAAGATACTACTGCCTTCTTTCCG
TCATATGACTTTATTATTGTTGGCTCAGGTTCAGCAGGAAGTGTTTTAGCAAATCGTTTA
AGTGAAAACAAAAAATGGCGTGTATTATTACTTGAAGCTGGAAGACAAGAAACATTTCTC
ACAGATGTCCCATTAACAGCATCAGTTAATTCTGCTACGTCACATAATTGGGGTTATCGG
ACAGATCCAAATACACAAAATGCTTGCTTAGGATTAGAGCAAGGTGTCTGTAACTGGCCG
AAAGGTCGTGTTCTCGGTGGTACAAGCGTTCTTAATTTTCTAATTTATACTCGAGGTCAT
AGGCGAGATTATGATCATTGGGCAGAACTGGGGAATTACGGATGGAGCTACAGTGAAGTC
TTGCCATATTTTATTAAAACTGAAAATGTTAAAATACCATCTTTAAGAAATTCACGCTAC
AGAGGTAAATCTGGGTTTTTAGATATAGAATATGCACCGTATACGTCACCTTTGCATCAG
AGTTTCAAAGAAGCTGGTTATGAATTGGGATATAATTATAATGATCCAAATGCTGAGCAG
CAACTTGGGTTTTCATTAGCACAAGCAACTATGAGAAATGGAAGAAGACTTAGTGCAGCT
AAAGCTTACTTAAGATCAGTAGCTTCCTCAAGAGATAATTTGCATATTTCATTAAATTCT
TGGGTCACTAGAGTTGTTATAGATCCATTTACTAAAATGACACTTGGTGTTGAATTTGTT
AAGAATCGTAAAAAATATTTCATTAAGTCAAAGAAGGAAGTAATTTTGTCTGCAGGAACA
ATTGGTTCAGCTCAGCTTTTATTACTTTCAGGTGTTGGTCCAAAAGAACATTTAGCAGAA
TTCAACATACCAACATTTTCAAATCTGAAAACAGGTTACAACCTTCAAGATCATGCATCT
CTGGCAGGTTTAACGTTTTTAGTAAATCAGCCGGTTACCGTATTAGAACAAAACATGAGA
AGACCACGATTTATGCTCGAATATTTGCTTGCAAATACTGGACCTCTGACTTTACCAGCT
GGTGCGGAAGGTATTGCTTTTGTGAAAACAAATGTATCATATTTACCTGCTGATTATCCT
GATATTGAACTTGTCATGGGAATCGGCAGCTTTACCGGAGACACGAGCGGTTTTCTTAGA
AATGTTTTTGGTATCACTAAAGAATTTACCGACAAAGTATATGGAAATGTAAAAGGACAC
CATGCATTCACTATTGCACCAGTTTTGATGCGTCCAAAAAGTAGAGGAAGAATTTTTCTC
AAATCCAAAAATCCGTTTCATCATCCACACCTACAACCCAATTTTTATTCAAGACAAGAA
GATTTAATTGTGCTTCGTGAAGGAATAAAGATGGCATTGAAAGTCGGCGAATCAAATGCA
TTTAAAAAATTTGGAACAAGATTTCATGATGTTCCTTATTTGGGATGTGAACATTTGCCA
TTTCGATCTGATGACTATTGGGACTGTTGCATACATCGCATTGCAAGTTCTTTGCAGCAT
CAAGTTGGAACATGTAAAATGGGAGTTGACGCGGACTCAGTTGTTGATCCAGAATTGAGA
GTATACGGCATTCGAAATTTGCGTGTAGCAGATGGTTCAATAATGCCAGTCATTCCAGCG
TCTCATACAAATTCTGTTATATTTATGATTGGTGAAAAAGCAAGCGACATGATTAAAAAA
ACATGGGGTTCTTCTTAA
>g11861.t1 Gene=g11861 Length=585
MNYLIYNSSSIIEDTTAFFPSYDFIIVGSGSAGSVLANRLSENKKWRVLLLEAGRQETFL
TDVPLTASVNSATSHNWGYRTDPNTQNACLGLEQGVCNWPKGRVLGGTSVLNFLIYTRGH
RRDYDHWAELGNYGWSYSEVLPYFIKTENVKIPSLRNSRYRGKSGFLDIEYAPYTSPLHQ
SFKEAGYELGYNYNDPNAEQQLGFSLAQATMRNGRRLSAAKAYLRSVASSRDNLHISLNS
WVTRVVIDPFTKMTLGVEFVKNRKKYFIKSKKEVILSAGTIGSAQLLLLSGVGPKEHLAE
FNIPTFSNLKTGYNLQDHASLAGLTFLVNQPVTVLEQNMRRPRFMLEYLLANTGPLTLPA
GAEGIAFVKTNVSYLPADYPDIELVMGIGSFTGDTSGFLRNVFGITKEFTDKVYGNVKGH
HAFTIAPVLMRPKSRGRIFLKSKNPFHHPHLQPNFYSRQEDLIVLREGIKMALKVGESNA
FKKFGTRFHDVPYLGCEHLPFRSDDYWDCCIHRIASSLQHQVGTCKMGVDADSVVDPELR
VYGIRNLRVADGSIMPVIPASHTNSVIFMIGEKASDMIKKTWGSS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g11861.t1 | Gene3D | G3DSA:3.50.50.60 | - | 22 | 579 | 1.3E-169 |
| 9 | g11861.t1 | Gene3D | G3DSA:3.30.560.10 | Glucose Oxidase | 59 | 519 | 1.3E-169 |
| 3 | g11861.t1 | PANTHER | PTHR11552:SF216 | GLUCOSE DEHYDROGENASE [FAD, QUINONE]-LIKE PROTEIN | 4 | 583 | 7.9E-275 |
| 4 | g11861.t1 | PANTHER | PTHR11552 | GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE | 4 | 583 | 7.9E-275 |
| 10 | g11861.t1 | PIRSF | PIRSF000137 | Alcohol_oxidase | 9 | 585 | 3.6E-142 |
| 1 | g11861.t1 | Pfam | PF00732 | GMC oxidoreductase | 22 | 319 | 4.4E-68 |
| 2 | g11861.t1 | Pfam | PF05199 | GMC oxidoreductase | 432 | 574 | 1.2E-34 |
| 7 | g11861.t1 | ProSitePatterns | PS00623 | GMC oxidoreductases signature 1. | 102 | 125 | - |
| 6 | g11861.t1 | SUPERFAMILY | SSF51905 | FAD/NAD(P)-binding domain | 21 | 583 | 6.85E-76 |
| 5 | g11861.t1 | SUPERFAMILY | SSF54373 | FAD-linked reductases, C-terminal domain | 314 | 524 | 1.57E-37 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors | MF |
| GO:0050660 | flavin adenine dinucleotide binding | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed