General information for g11876.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative fatty acyl-CoA reductase CG5065.
Parent gene
- The parent gene g11876 is located on chr_1: 18937893..18939756 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11876 | g11876.t1 | isoform | g11876.t1 | 18936245 | 18937893 |
| chr_1 | g11876 | g11876.t1 | exon | g11876.t1.exon1 | 18936245 | 18936308 |
| chr_1 | g11876 | g11876.t1 | cds | g11876.t1.CDS1 | 18936245 | 18936308 |
| chr_1 | g11876 | g11876.t1 | exon | g11876.t1.exon2 | 18936374 | 18936505 |
| chr_1 | g11876 | g11876.t1 | cds | g11876.t1.CDS2 | 18936374 | 18936505 |
| chr_1 | g11876 | g11876.t1 | exon | g11876.t1.exon3 | 18936559 | 18937756 |
| chr_1 | g11876 | g11876.t1 | cds | g11876.t1.CDS3 | 18936559 | 18937756 |
| chr_1 | g11876 | g11876.t1 | exon | g11876.t1.exon4 | 18937815 | 18937893 |
| chr_1 | g11876 | g11876.t1 | cds | g11876.t1.CDS4 | 18937815 | 18937893 |
| chr_1 | g11876 | g11876.t1 | TSS | g11876.t1 | NA | NA |
| chr_1 | g11876 | g11876.t1 | TTS | g11876.t1 | NA | NA |
Sequences
>g11876.t1 Gene=g11876 Length=1473
ATGACAAATTCATCAATATCTAATTACTATATAGGCAAAAATGTGTTGATTACGGGAGCA
ACAGGGTTTATGGGGAAAGTATTGGTTCAAAAATTGCTTCATGATTGCTGTGAAATATCT
AAAATATACATACTTGTACGACCAAAGAAAGGCATTGATTCTGAACAAAGATGTCTTGAT
TATAAAAATCATATTGTATTTGAGAAAATAAGACAAGAAATGCCTTTGCAGTTGGATAAA
ATTCAAATGATAAAAGGAGACGTAACTATGGATAATTTAGGTCTCAATTCAAGCGATGAG
AAAGAATTGATAGAAAATGTGAATATAATTTTTCATTGTGCTGCAAATGTGCGGTTTGAT
TTGACTCTCAAAGATGCCACAAATTTCAATTTGAAGGGGACTCTAAGAGTGCTTACTCTT
GCAGAGAAAATGCAAAGTCTTAACTCATTTGTGCATGTTTCCACTTCTTACTGTAATTGT
GATGAAGTGGTTTTAGAGGAGAAATACTATCCCGCTAAAGTAGATCCATTTACTGTAATT
GAAATGATTGACACAATGAGTGATGATGCCTTAAAATCAGTTACGCCTAAATTACTTGGA
AAACTTCCAAATACTTATGCATTAACTAAAGGCTATTCAGAAGATTTAGTCAACTCATAT
AGAAAGAAATTTCCTATTGTTATTGCACGACCTCCTATTGTTGTCGCATCATGGAAAGAA
CCATTTCCTGGTTTTATTGAAGGCGTTAATGGACCAACAGGACTTATGATTGGAGCTGCT
AAAGGTGTTATAAGGTCAATGCATTGCAATCCTAAATATCCATCAGAAGCTATTCCTGTT
GACATTATAATTAATTGTCTGATTGCATTGGCTTTTAAAAGATCTTTGATTAAGAATGAA
GAAGTTTTCTATTGTAACATAACAGATAGTGGAACAAATTCTCTTACATGGGGTGAATCT
TTAGAGTTGGGAAAGAAAATTTTCTATAAATATCCTCTAAGTACTACATGTCTTTACTAT
CCAAACGGTTCAATGAAATCAAATTATTTTCTGCATACATTGTGCATCATTTTTACACAT
TACCTTCCAGCTTATATAATTGATGGTATTTTATATATTTTTGGGTATGAAACCTTTTTG
GTAAATATTCAAAAGCGGATCAGTCAAGGATTGAAAGTATTGCAATATTACACTACACGT
GAATGGCTTTTTAAAAATGAAAATTTTCGAAAATTGCGTGATGACATGAATGCTATTGAT
CAACAAAGGTTCTATTGTGATTTATCTAAAATCGATTACAATGACTATATTTTAAATTAC
ATACTGGGAATAAGAAAATTCATTTTAAATGAATCTTTAAGTTCACTACCAAAGGCTCGA
GCAAAATTAATGAGACTCTATTATATTGATAAACTTCTGAAAATATTCTTCTGTGGACTT
ATTATTTACATAATTTATAATCTTTTAAAATAA
>g11876.t1 Gene=g11876 Length=490
MTNSSISNYYIGKNVLITGATGFMGKVLVQKLLHDCCEISKIYILVRPKKGIDSEQRCLD
YKNHIVFEKIRQEMPLQLDKIQMIKGDVTMDNLGLNSSDEKELIENVNIIFHCAANVRFD
LTLKDATNFNLKGTLRVLTLAEKMQSLNSFVHVSTSYCNCDEVVLEEKYYPAKVDPFTVI
EMIDTMSDDALKSVTPKLLGKLPNTYALTKGYSEDLVNSYRKKFPIVIARPPIVVASWKE
PFPGFIEGVNGPTGLMIGAAKGVIRSMHCNPKYPSEAIPVDIIINCLIALAFKRSLIKNE
EVFYCNITDSGTNSLTWGESLELGKKIFYKYPLSTTCLYYPNGSMKSNYFLHTLCIIFTH
YLPAYIIDGILYIFGYETFLVNIQKRISQGLKVLQYYTTREWLFKNENFRKLRDDMNAID
QQRFYCDLSKIDYNDYILNYILGIRKFILNESLSSLPKARAKLMRLYYIDKLLKIFFCGL
IIYIIYNLLK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g11876.t1 | CDD | cd05236 | FAR-N_SDR_e | 13 | 332 | 8.15336E-121 |
| 15 | g11876.t1 | CDD | cd09071 | FAR_C | 358 | 449 | 1.40019E-36 |
| 8 | g11876.t1 | Gene3D | G3DSA:3.40.50.720 | - | 5 | 339 | 1.2E-67 |
| 3 | g11876.t1 | PANTHER | PTHR11011 | MALE STERILITY PROTEIN 2-RELATED | 3 | 487 | 3.6E-153 |
| 4 | g11876.t1 | PANTHER | PTHR11011:SF12 | FATTY ACYL-COA REDUCTASE | 3 | 487 | 3.6E-153 |
| 1 | g11876.t1 | Pfam | PF07993 | Male sterility protein | 17 | 285 | 3.4E-72 |
| 2 | g11876.t1 | Pfam | PF03015 | Male sterility protein | 360 | 451 | 4.1E-30 |
| 10 | g11876.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 348 | - |
| 12 | g11876.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 349 | 376 | - |
| 9 | g11876.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 377 | 471 | - |
| 13 | g11876.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 472 | 489 | - |
| 11 | g11876.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 490 | 490 | - |
| 7 | g11876.t1 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 5 | 303 | 1.53E-33 |
| 5 | g11876.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 354 | 376 | - |
| 6 | g11876.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 472 | 489 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity | MF |
KEGG
Orthology
- This transcript has been annotated with K13356 (alcohol-forming fatty acyl-CoA reductase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
