General information for g11946.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Glutathione S-transferase E14.
Parent gene
- The parent gene g11946 is located on chr_1: 19563824..19565053 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11946 | g11946.t1 | TTS | g11946.t1 | 19563647 | 19563647 |
| chr_1 | g11946 | g11946.t1 | isoform | g11946.t1 | 19563824 | 19565053 |
| chr_1 | g11946 | g11946.t1 | exon | g11946.t1.exon1 | 19563824 | 19564162 |
| chr_1 | g11946 | g11946.t1 | cds | g11946.t1.CDS1 | 19563824 | 19564162 |
| chr_1 | g11946 | g11946.t1 | exon | g11946.t1.exon2 | 19564231 | 19564375 |
| chr_1 | g11946 | g11946.t1 | cds | g11946.t1.CDS2 | 19564231 | 19564375 |
| chr_1 | g11946 | g11946.t1 | exon | g11946.t1.exon3 | 19564434 | 19564492 |
| chr_1 | g11946 | g11946.t1 | cds | g11946.t1.CDS3 | 19564434 | 19564492 |
| chr_1 | g11946 | g11946.t1 | exon | g11946.t1.exon4 | 19564558 | 19564606 |
| chr_1 | g11946 | g11946.t1 | cds | g11946.t1.CDS4 | 19564558 | 19564606 |
| chr_1 | g11946 | g11946.t1 | exon | g11946.t1.exon5 | 19564725 | 19564784 |
| chr_1 | g11946 | g11946.t1 | cds | g11946.t1.CDS5 | 19564725 | 19564784 |
| chr_1 | g11946 | g11946.t1 | exon | g11946.t1.exon6 | 19564842 | 19564939 |
| chr_1 | g11946 | g11946.t1 | cds | g11946.t1.CDS6 | 19564842 | 19564939 |
| chr_1 | g11946 | g11946.t1 | exon | g11946.t1.exon7 | 19565042 | 19565053 |
| chr_1 | g11946 | g11946.t1 | cds | g11946.t1.CDS7 | 19565042 | 19565053 |
| chr_1 | g11946 | g11946.t1 | TSS | g11946.t1 | NA | NA |
Sequences
>g11946.t1 Gene=g11946 Length=762
ATGTTGATGTATTCTTACACAAAATCTTTTTTTGTCAGTCTTAATTCAACTAGTAAAGAA
GATAGAAGTAAAATGTCTAAAACTCCAATTTATTATTATCATTTAATGAGTCCACCATCT
CGTGCTGGTCTAATGATTATAAAAGAACTTGATTTAAATATAAAATTACAAGAAATCGAT
CTTTTAAATAGTGAAAATTTTTCAGAAGAATTTACAAAGATCAATCCATCTCAAACAGTT
CCATCATTAGTTGATGATGATTTTATTGTATGTGACAGTCATGCAATTTGTCTTTATTTG
ATTGAAAAATATGCTAAGAATGACAAACTCTATCCTAAAGATGATATTGCTTTGCGTACT
AAAATCAACGATCGTTTATTTTTTGATGCAAGTTTTCTATTTCCACGTGGATATAATATT
ATGATTCCGGTTTTAATGCAAGGTCAATCTTTTATTCCTGAAGAGAATATCAATCAATTT
TATCGTGCCTTTAAAGTTGTTGAAAGTTTTTTAGAAAATTCAAAATGGATTGCATCTAAC
GATCAAATGACTTTGGCTGATATCGCTATTTTTGCATGGATGGAATGTTATACCCAACTT
TTTACTATTGAAGACTATCCAAAATTAACAGCTTGGTTAAATGAAATGAGAAAATTGTCA
TATTATGAAGAAGCGAACAAAAAAGGAGCTAAGCTTCAAGTTGAAACTTTTCAACGTGTT
TTGGAAAATAACAAGAAAAAAATTTTAAATGAAAGTGTTTGA
>g11946.t1 Gene=g11946 Length=253
MLMYSYTKSFFVSLNSTSKEDRSKMSKTPIYYYHLMSPPSRAGLMIIKELDLNIKLQEID
LLNSENFSEEFTKINPSQTVPSLVDDDFIVCDSHAICLYLIEKYAKNDKLYPKDDIALRT
KINDRLFFDASFLFPRGYNIMIPVLMQGQSFIPEENINQFYRAFKVVESFLENSKWIASN
DQMTLADIAIFAWMECYTQLFTIEDYPKLTAWLNEMRKLSYYEEANKKGAKLQVETFQRV
LENNKKKILNESV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g11946.t1 | CDD | cd03177 | GST_C_Delta_Epsilon | 119 | 231 | 0.000 |
| 8 | g11946.t1 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 6 | 107 | 0.000 |
| 7 | g11946.t1 | Gene3D | G3DSA:1.20.1050.10 | - | 108 | 248 | 0.000 |
| 3 | g11946.t1 | PANTHER | PTHR43969:SF4 | FI01423P-RELATED | 25 | 242 | 0.000 |
| 4 | g11946.t1 | PANTHER | PTHR43969 | GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED | 25 | 242 | 0.000 |
| 2 | g11946.t1 | Pfam | PF13417 | Glutathione S-transferase, N-terminal domain | 36 | 106 | 0.000 |
| 1 | g11946.t1 | Pfam | PF00043 | Glutathione S-transferase, C-terminal domain | 154 | 217 | 0.000 |
| 10 | g11946.t1 | ProSiteProfiles | PS50404 | Soluble glutathione S-transferase N-terminal domain profile. | 27 | 108 | 21.210 |
| 9 | g11946.t1 | ProSiteProfiles | PS50405 | Soluble glutathione S-transferase C-terminal domain profile. | 115 | 238 | 14.528 |
| 12 | g11946.t1 | SFLD | SFLDG01153 | Main.4: Theta-like | 29 | 241 | 0.000 |
| 13 | g11946.t1 | SFLD | SFLDS00019 | Glutathione Transferase (cytosolic) | 29 | 241 | 0.000 |
| 5 | g11946.t1 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 29 | 113 | 0.000 |
| 6 | g11946.t1 | SUPERFAMILY | SSF47616 | GST C-terminal domain-like | 115 | 232 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006749 | glutathione metabolic process | BP |
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K00799 (glutathione S-transferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed