General information for g12054.t57
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Glutathione hydrolase 1 proenzyme.
Parent gene
- The parent gene g12054 is located on chr_1: 20676680..20679505 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12054 | g12054.t57 | isoform | g12054.t57 | 20672656 | 20673374 |
| chr_1 | g12054 | g12054.t57 | exon | g12054.t57.exon1 | 20672656 | 20673374 |
| chr_1 | g12054 | g12054.t57 | cds | g12054.t57.CDS1 | 20672658 | 20673116 |
| chr_1 | g12054 | g12054.t57 | TSS | g12054.t57 | NA | NA |
| chr_1 | g12054 | g12054.t57 | TTS | g12054.t57 | NA | NA |
Sequences
>g12054.t57 Gene=g12054 Length=719
AAAGTTGTTTTGTTAAAGCAATGTGATTTCTTAGAATTATTAAGTAAACAAAATACCACA
GAGGACATTTTTTCTGGAGATGTGGGAAAATTATTAGCTGACGACCTAAAAACAGCAAAT
GCTATTGTAGATATAAATGATCTCCAAACATACAAAGTAAAAGTTTATGAAGCGAGAAAA
TTTGATTTAATAAATGACAACGTCCTTCTTGTGCCTAATACATGTGCAATATTAATTCCG
GCAATTTTAAATATTTTAATGAAATATAATTTCAATTCAACATGGTTTGATAGTCAACAC
AATACTAATTTATCAATTTTAATGCATCATCGAATAATTGAGACTTTTAAGCATGTGTTT
GCAATGAGATCTGAAATGAGTGATTCAGATTTCATGGATACTGAAAATATCATTAATTAT
CTACTTTCAAATGATTTTGCCTATAATGTAATAAAATCTATTAATGACTCGTTTGTAAAG
CCTTATCTACAGGATTACAATTTATCAACAATTGTTCCACAAAATCATGGAACATCTCAC
ATTTCGATAGTTGCTGAAAATAATGACTTGATATCTGTTACAAGCTCAATAAATTTTTAT
TTTGGCTCTGGAATTATTGGCTCTAAATCGGGTTTAATTTTTAATAATGGTATGGATGAC
TTTTCTTATTTTAATCGATCTGTAAATTACTTTGGATTGAAAGAGACACCCACTAATTT
>g12054.t57 Gene=g12054 Length=153
MKYNFNSTWFDSQHNTNLSILMHHRIIETFKHVFAMRSEMSDSDFMDTENIINYLLSNDF
AYNVIKSINDSFVKPYLQDYNLSTIVPQNHGTSHISIVAENNDLISVTSSINFYFGSGII
GSKSGLIFNNGMDDFSYFNRSVNYFGLKETPTN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g12054.t57 | Gene3D | G3DSA:1.10.246.130 | - | 1 | 83 | 0 |
| 7 | g12054.t57 | Gene3D | G3DSA:3.60.20.40 | - | 86 | 153 | 0 |
| 2 | g12054.t57 | PANTHER | PTHR11686:SF9 | RE13973P | 14 | 153 | 0 |
| 3 | g12054.t57 | PANTHER | PTHR11686 | GAMMA GLUTAMYL TRANSPEPTIDASE | 14 | 153 | 0 |
| 5 | g12054.t57 | PRINTS | PR01210 | Gamma-glutamyltranspeptidase signature | 92 | 110 | 0 |
| 4 | g12054.t57 | PRINTS | PR01210 | Gamma-glutamyltranspeptidase signature | 116 | 134 | 0 |
| 1 | g12054.t57 | Pfam | PF01019 | Gamma-glutamyltranspeptidase | 20 | 153 | 0 |
| 6 | g12054.t57 | SUPERFAMILY | SSF56235 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 12 | 153 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006751 | glutathione catabolic process | BP |
| GO:0036374 | glutathione hydrolase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed