General information for g12126.t9
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Mitogen-activated protein kinase kinase kinase kinase 3.
Parent gene
- The parent gene g12126 is located on chr_1: 21184495..21185582 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12126 | g12126.t9 | isoform | g12126.t9 | 21184495 | 21185582 |
| chr_1 | g12126 | g12126.t9 | exon | g12126.t9.exon1 | 21184495 | 21184526 |
| chr_1 | g12126 | g12126.t9 | cds | g12126.t9.CDS1 | 21184495 | 21184526 |
| chr_1 | g12126 | g12126.t9 | exon | g12126.t9.exon2 | 21184595 | 21184688 |
| chr_1 | g12126 | g12126.t9 | cds | g12126.t9.CDS2 | 21184595 | 21184688 |
| chr_1 | g12126 | g12126.t9 | exon | g12126.t9.exon3 | 21184795 | 21185089 |
| chr_1 | g12126 | g12126.t9 | cds | g12126.t9.CDS3 | 21184795 | 21185046 |
| chr_1 | g12126 | g12126.t9 | exon | g12126.t9.exon4 | 21185268 | 21185399 |
| chr_1 | g12126 | g12126.t9 | exon | g12126.t9.exon5 | 21185496 | 21185582 |
| chr_1 | g12126 | g12126.t9 | TSS | g12126.t9 | 21185641 | 21185641 |
| chr_1 | g12126 | g12126.t9 | TTS | g12126.t9 | NA | NA |
Sequences
>g12126.t9 Gene=g12126 Length=640
ATGCAGCCGATATACAAAAGTAATCCGCATGAAGATTACGAGTTGTTGCAGAAAATAGGC
TCAGGCACTTATGGGAGTGTGTATAAAGGAAGGAATGTAAAAACGGGCGAATATGCAGCT
ATTAAAGTCATAAAAATAGAAACGGGCGATGACTTTCAACAGATCGAACAAGAAATCACC
ATGCTCAAGGGCTGCAATCATAAAAACATCATAAGGTGATTACTATGGCTCATATCTTCG
TCGAGATAAATTGTGGATATGCATGGAATTGTGTGCGTACAGCTTGCAAGATATTTATCA
AGTCATTGGACCACTGACAGAACAGCAAATAGCATACGTGTGTCGAGAAACGTTACTTGG
TTTACAATATTTGCATAATCGAGGAAAGATGCATAGAGATATCAAGGGAGCCAATATTTT
GTTGACTGACAATGGTGATGTAAAATTAGCTGATTTTGGAGTGTCTGCACAAATCACTGC
AACAATTAATAAGCGGAAAAGTTTTATTGGAACTCCATATTGGATGAGTCCAGAAGTTGC
TGCAGTTGAAAGAAAAGGAGGATATAATCATTTGTGTGATATTTGGGCGGTTGGGATTAC
TGCTATTGAACTTGCTGAGCTTCAACCCCCGATGTTTGAG
>g12126.t9 Gene=g12126 Length=126
MELCAYSLQDIYQVIGPLTEQQIAYVCRETLLGLQYLHNRGKMHRDIKGANILLTDNGDV
KLADFGVSAQITATINKRKSFIGTPYWMSPEVAAVERKGGYNHLCDIWAVGITAIELAEL
QPPMFE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g12126.t9 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 1 | 126 | 0.00 |
| 2 | g12126.t9 | PANTHER | PTHR48012:SF18 | HAPPYHOUR, ISOFORM A | 1 | 126 | 0.00 |
| 3 | g12126.t9 | PANTHER | PTHR48012 | STERILE20-LIKE KINASE, ISOFORM B-RELATED | 1 | 126 | 0.00 |
| 1 | g12126.t9 | Pfam | PF00069 | Protein kinase domain | 1 | 124 | 0.00 |
| 7 | g12126.t9 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 1 | 126 | 29.39 |
| 5 | g12126.t9 | SMART | SM00220 | serkin_6 | 1 | 125 | 0.00 |
| 4 | g12126.t9 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 1 | 125 | 0.00 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed