General information for g12133.t6
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Adenosylhomocysteinase.
Parent gene
- The parent gene g12133 is located on chr_1: 21225692..21227548 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12133 | g12133.t6 | TTS | g12133.t6 | 21223774 | 21223774 |
| chr_1 | g12133 | g12133.t6 | isoform | g12133.t6 | 21223779 | 21224681 |
| chr_1 | g12133 | g12133.t6 | exon | g12133.t6.exon1 | 21223779 | 21224414 |
| chr_1 | g12133 | g12133.t6 | cds | g12133.t6.CDS1 | 21223873 | 21224414 |
| chr_1 | g12133 | g12133.t6 | exon | g12133.t6.exon2 | 21224476 | 21224681 |
| chr_1 | g12133 | g12133.t6 | cds | g12133.t6.CDS2 | 21224476 | 21224560 |
| chr_1 | g12133 | g12133.t6 | TSS | g12133.t6 | NA | NA |
Sequences
>g12133.t6 Gene=g12133 Length=842
TCTGTTACCAAGAGCAAATTCGATAATCTCTATGGATGCCGTGAATCTTTAATTGATGGA
ATTAAGCGTGCTACTGATGTCATGATTGCAGGAAAAGTGTGTGTTGTTGCTGGTTATGGA
GATGTTGGTAAAGGTTGTGCTCAAGCTCTTCGATCATTTGGCGGCAGAGTTATTATTACA
GAAATTGATCCAATCAATGCTCTGCACAATGGAAGGATATGAAGTAACAACTATGGATGA
AGCAGCCAGTGAAGGAAATATTTTTGTTACAACAACTGGTTGCACAGACATCATTATGGG
AGATCATTTTATGAAAATGAAAGATGATTCAATTGTTTGTAATATTGGTCATTTTGATTG
TGAAGTTAACGTAGCTTGGCTTGAAGAAAATGCAAAGGAAAAAGTCAATATTAAGCCACA
AGTTGATAGATTTGTTTTAAGTAACGGCAATCACATTATTCTTTTGGCTGAAGGACGATT
GGTTAATCTCGGTTGTGCCAAGGGCCATCCATCGTTTGTGATGTCAAATTCTTTCTGTAA
CCAGACACTTGCCCAAATTGAGCTTTGGACTAAAGCTGAAAAATATCCAGTTGGAGTTCA
TATGTTACCTAAGAAACTTGATGAGGAAGTCGCAGCACTTCATCTTGAAAAATTGGGAGT
AAAACTTACAAAACTCACAGAAAAGCAAGCTAAATATTTGGGACTTTGTGCAGAAGGACC
ATTCAAACCTGAATACTATCGCTACTAATTGTTGCATTTTTTTACCATATAATCATCATC
TGTGTGTGTACTGAATTAAAATTAAAAAATAAAATGTGGAATCATTGGGAACTTCTTTTA
AA
>g12133.t6 Gene=g12133 Length=208
MLVKVVLKLFDHLAAELLLQKLIQSMLCTMEGYEVTTMDEAASEGNIFVTTTGCTDIIMG
DHFMKMKDDSIVCNIGHFDCEVNVAWLEENAKEKVNIKPQVDRFVLSNGNHIILLAEGRL
VNLGCAKGHPSFVMSNSFCNQTLAQIELWTKAEKYPVGVHMLPKKLDEEVAALHLEKLGV
KLTKLTEKQAKYLGLCAEGPFKPEYYRY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g12133.t6 | Gene3D | G3DSA:3.40.50.720 | - | 19 | 124 | 0 |
| 10 | g12133.t6 | Gene3D | G3DSA:3.40.50.1480 | - | 125 | 208 | 0 |
| 3 | g12133.t6 | PANTHER | PTHR23420 | ADENOSYLHOMOCYSTEINASE | 23 | 208 | 0 |
| 4 | g12133.t6 | PANTHER | PTHR23420:SF20 | ADENOSYLHOMOCYSTEINASE | 23 | 208 | 0 |
| 2 | g12133.t6 | Pfam | PF00670 | S-adenosyl-L-homocysteine hydrolase, NAD binding domain | 23 | 128 | 0 |
| 1 | g12133.t6 | Pfam | PF05221 | S-adenosyl-L-homocysteine hydrolase | 129 | 207 | 0 |
| 8 | g12133.t6 | SMART | SM00996 | AdoHcyase_2 | 1 | 207 | 0 |
| 7 | g12133.t6 | SMART | SM00997 | AdoHcyase_NAD_2 | 2 | 128 | 0 |
| 5 | g12133.t6 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 25 | 129 | 0 |
| 6 | g12133.t6 | SUPERFAMILY | SSF52283 | Formate/glycerate dehydrogenase catalytic domain-like | 50 | 208 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
