General information for g12150.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Blood vessel epicardial substance.
Parent gene
- The parent gene g12150 is located on chr_1: 21407301..21408489 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12150 | g12150.t1 | TSS | g12150.t1 | 21400977 | 21400977 |
| chr_1 | g12150 | g12150.t1 | isoform | g12150.t1 | 21401615 | 21408039 |
| chr_1 | g12150 | g12150.t1 | exon | g12150.t1.exon1 | 21401615 | 21402046 |
| chr_1 | g12150 | g12150.t1 | cds | g12150.t1.CDS1 | 21401615 | 21402046 |
| chr_1 | g12150 | g12150.t1 | exon | g12150.t1.exon2 | 21406605 | 21406762 |
| chr_1 | g12150 | g12150.t1 | cds | g12150.t1.CDS2 | 21406605 | 21406762 |
| chr_1 | g12150 | g12150.t1 | exon | g12150.t1.exon3 | 21406842 | 21407088 |
| chr_1 | g12150 | g12150.t1 | cds | g12150.t1.CDS3 | 21406842 | 21407088 |
| chr_1 | g12150 | g12150.t1 | exon | g12150.t1.exon4 | 21407157 | 21407301 |
| chr_1 | g12150 | g12150.t1 | cds | g12150.t1.CDS4 | 21407157 | 21407301 |
| chr_1 | g12150 | g12150.t1 | exon | g12150.t1.exon5 | 21407702 | 21408039 |
| chr_1 | g12150 | g12150.t1 | cds | g12150.t1.CDS5 | 21407702 | 21408039 |
| chr_1 | g12150 | g12150.t1 | TTS | g12150.t1 | NA | NA |
Sequences
>g12150.t1 Gene=g12150 Length=1320
ATGGTATTAGTAGATAGTGAAGTTAATCAGTCTTATGTGACTGAAAGTGCAAATATACAC
AACTCTGATCCTCACAGCGAATCAAGCAATAACAACAATGACCTTGTATCACCGCATGTG
TTTAATTTACTCCAAAATTTTATCGCTGCTCAATGTGAAGCTACTTATTCATTGCAACCG
CTTTACTATCACATCGGCTGTGCTTTCTTCCTATTAGCGTTCTTAGCACCAGGTTATCGC
TATGGAACTGCATTATATATGCGATGCATGCTAACATTTGGTTGTATTCTATTTCTTATG
TGGTCATATCTCGTTGAGTGTAGACCCGATGTGCTCATATGGACACTCTTATTCATCTTT
GTTAACATCATACACATGGCAATCTTAATTTGTAAACTGAGACCGGTTAAGTTTGAGAAG
GAAATTGAAGAGGTATATGTTGCACTTTTTAAGCCACTACAAGTGTCACGTCGTCGCTTT
AAAAAAATTTTAAAATGCTTAAAAACTGTACGTAAATTCAAAAGTCAAGAAATTTATGTA
CAGGAGAAAATTTCAAAAGTTGATAGTCTATCTCTAGTTTTATCAGGAAAATTTGTTGTA
TCGCAAAACCAAAAAGCCCTTCATATTGTCTTTCCTAATCAGTTCCTTGACTCGCCTGAA
TATTTTGGTGTCAGTACAGACGATTATTTTAATGTTTCAATAACATGCATAGAAGATGCA
CGAGTTTTACAATGGCATCGAGATAAGCTCAAATTGTCGATTGACGAATATTTAAAAACA
ATGTTTGATCATATTTTAGCAAAGGATGTTGTGAAAAAATTAATGCAGGTATCACAGGTC
AGTGAAACAATGGCACAAAGTAATGGTTATATTGCAACAAATTGTGCATATGGTGAAGAT
GATAAACCTATGTTATTAATGAAAAAATCAATTGATAGTCAGGGAAATGGTTTGACAGCT
TTAATTAACAAGCAACTTCAAGCTGATAATTTCGAGCATGTGCCACTGCTAGTCACGCCA
TCACAATGTAAACCGAATGCATCAAGCTTAAAGAAGAACAATAAAGTGACAAATGGAAAT
GGTTTAATTGATATTATTGAACATCAGCAGCAACAACAGCCACAACAACAACAGGTTATG
ATGTCAAGCAACACTGCAGCTCATGTAATGAGATCTCGATTAAATCAGTATAAAACAAGC
AATGTAATTCTCAATTTTGATGAAAGTAATGGAATTGAAGTAAAAATTGATAAAGATACT
TCTTCATCTATATCATCACGTGCAAAGAATAAAAAGAAGAATTCTGTCGCTGATATTTAG
>g12150.t1 Gene=g12150 Length=439
MVLVDSEVNQSYVTESANIHNSDPHSESSNNNNDLVSPHVFNLLQNFIAAQCEATYSLQP
LYYHIGCAFFLLAFLAPGYRYGTALYMRCMLTFGCILFLMWSYLVECRPDVLIWTLLFIF
VNIIHMAILICKLRPVKFEKEIEEVYVALFKPLQVSRRRFKKILKCLKTVRKFKSQEIYV
QEKISKVDSLSLVLSGKFVVSQNQKALHIVFPNQFLDSPEYFGVSTDDYFNVSITCIEDA
RVLQWHRDKLKLSIDEYLKTMFDHILAKDVVKKLMQVSQVSETMAQSNGYIATNCAYGED
DKPMLLMKKSIDSQGNGLTALINKQLQADNFEHVPLLVTPSQCKPNASSLKKNNKVTNGN
GLIDIIEHQQQQQPQQQQVMMSSNTAAHVMRSRLNQYKTSNVILNFDESNGIEVKIDKDT
SSSISSRAKNKKKNSVADI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g12150.t1 | Gene3D | G3DSA:2.60.120.10 | Jelly Rolls | 149 | 285 | 3.9E-6 |
| 8 | g12150.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 419 | 439 | - |
| 2 | g12150.t1 | PANTHER | PTHR12101:SF1 | BVES | 11 | 346 | 1.7E-107 |
| 3 | g12150.t1 | PANTHER | PTHR12101 | POPEYE DOMAIN CONTAINING PROTEIN | 11 | 346 | 1.7E-107 |
| 1 | g12150.t1 | Pfam | PF04831 | Popeye protein conserved region | 59 | 279 | 1.0E-41 |
| 13 | g12150.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 60 | - |
| 14 | g12150.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 61 | 78 | - |
| 10 | g12150.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 79 | 84 | - |
| 16 | g12150.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 85 | 105 | - |
| 12 | g12150.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 106 | 110 | - |
| 15 | g12150.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 111 | 131 | - |
| 11 | g12150.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 132 | 439 | - |
| 7 | g12150.t1 | SUPERFAMILY | SSF51206 | cAMP-binding domain-like | 149 | 259 | 2.35E-7 |
| 4 | g12150.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 60 | 79 | - |
| 6 | g12150.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 83 | 105 | - |
| 5 | g12150.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 112 | 129 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
KEGG
Orthology
- This transcript has been annotated with K21108 (blood vessel epicardial substance)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
