General information for g12176.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Inositol-pentakisphosphate 2-kinase.
Parent gene
- The parent gene g12176 is located on chr_1: 21484453..21485791 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12176 | g12176.t1 | TTS | g12176.t1 | 21482244 | 21482244 |
| chr_1 | g12176 | g12176.t1 | isoform | g12176.t1 | 21482373 | 21485482 |
| chr_1 | g12176 | g12176.t1 | exon | g12176.t1.exon1 | 21482373 | 21482565 |
| chr_1 | g12176 | g12176.t1 | cds | g12176.t1.CDS1 | 21482373 | 21482565 |
| chr_1 | g12176 | g12176.t1 | exon | g12176.t1.exon2 | 21482624 | 21482986 |
| chr_1 | g12176 | g12176.t1 | cds | g12176.t1.CDS2 | 21482624 | 21482986 |
| chr_1 | g12176 | g12176.t1 | exon | g12176.t1.exon3 | 21483054 | 21483289 |
| chr_1 | g12176 | g12176.t1 | cds | g12176.t1.CDS3 | 21483054 | 21483289 |
| chr_1 | g12176 | g12176.t1 | exon | g12176.t1.exon4 | 21483369 | 21483577 |
| chr_1 | g12176 | g12176.t1 | cds | g12176.t1.CDS4 | 21483369 | 21483577 |
| chr_1 | g12176 | g12176.t1 | exon | g12176.t1.exon5 | 21483646 | 21483813 |
| chr_1 | g12176 | g12176.t1 | cds | g12176.t1.CDS5 | 21483646 | 21483813 |
| chr_1 | g12176 | g12176.t1 | exon | g12176.t1.exon6 | 21485216 | 21485297 |
| chr_1 | g12176 | g12176.t1 | cds | g12176.t1.CDS6 | 21485216 | 21485297 |
| chr_1 | g12176 | g12176.t1 | exon | g12176.t1.exon7 | 21485375 | 21485482 |
| chr_1 | g12176 | g12176.t1 | cds | g12176.t1.CDS7 | 21485375 | 21485482 |
| chr_1 | g12176 | g12176.t1 | TSS | g12176.t1 | 21485791 | 21485791 |
Sequences
>g12176.t1 Gene=g12176 Length=1359
ATGTACAACAAAACATTGACTAATGTCAATAGTAATCTACAAGAGATTGTAGTCACGTTA
GGTGATTCCTGTCTCGAGAAAGTTCTTTCGTATCGTGATGAAGGCAATATGAATATTGTC
GTGAGTTTGAACACGCAAGGAAATGATGAGAAATATGTAATTCGTTTTAAAAAAATTTCA
TCTGATGTCGATGAAAAACAGCAAAATTTCAACGATCATAAGCATGAACTGATGTCCTTC
ATACATTTTGAGGAATTGCTACAAAAATATTTTGATCATTTTACCGTCGTGCCAAAAATA
GCTTTTGTTGATGTCGATATAAGCGCACTAAATGAATTTTTAATGCGTGACCGACCAGTT
GTAAGAAGAACAAAAGTTATTGGTCATAACTATGGACTTTTATATAGAGATGTGGCATTT
TTACCAAAAGAAATTTACATTGGCAAACAAATAAATGGCGAATTCAAGGATTCACCAACA
ATTTGTATTGAGATAAAAGTGAAACAAGGATATGTTATGACAAATGATGACCAATGTGCT
CAAAAATGTAGATATTGCTACTTTCAGTATTTAAAACTCAAAAATGCAAAAATAACTCAA
ATCTCAAGCTACTGCCCAATTGACCTTTTCTCAGGCAACGCAGAACGAATGAATCGTGCT
ATAAAAGGGCTCTTTGATAATCCACAGAATAATTTGAAAATGTTTCAAGACGGTAAAATG
GTTTATAATGAATATTCGCCTGATAAGCACTCACTAAAACGCATAATGAAAAGCCTTTTT
CCGGATGTTAAAAGTGTTGATAAACAGGAAATTTTAATGATAAATTTGATTCGAAAAATT
TTAACAAAAGATTTTACATGCTGTGATAATGAAATAGAAATTTGTACTGGATATGAAAGC
ACTGAAAATGTTCATTTAAGAAGATGCATTGGTGAAATGTTTTCGGAACTACCGAGCAAC
TGCATTTTGAGCAGCATATTAAAAGCACAGCATCTAGTTGGTGATAATCTTACAAATATG
GAGTTTTTTGAAAAAGAAGGAATGAATGCAATTGATGGTTATGAAAAAATTGTACAAGAT
TATAGATTGGGAAGCACTGCATTAGATTGTTCTGTTATGATTACACTAAGAAAAGTCAAT
TGCAATGAAAGTTTTGATAATGAAATCGAAAAATTAGTAAACAAAAACCATTATCTCAGA
CTTAATGTACCAGGAAGAAGTGTTCAGCATTTTGCAGTAAATGTGACAGTCGTTGATTTA
GATGAGAAAAAAGATGCACTGGCACATTATCGAAAGTACAAGAAGCAATACATGGAAAGT
AAATTTGCTTATTATGAATTCATGAAAAGTATTCAATAA
>g12176.t1 Gene=g12176 Length=452
MYNKTLTNVNSNLQEIVVTLGDSCLEKVLSYRDEGNMNIVVSLNTQGNDEKYVIRFKKIS
SDVDEKQQNFNDHKHELMSFIHFEELLQKYFDHFTVVPKIAFVDVDISALNEFLMRDRPV
VRRTKVIGHNYGLLYRDVAFLPKEIYIGKQINGEFKDSPTICIEIKVKQGYVMTNDDQCA
QKCRYCYFQYLKLKNAKITQISSYCPIDLFSGNAERMNRAIKGLFDNPQNNLKMFQDGKM
VYNEYSPDKHSLKRIMKSLFPDVKSVDKQEILMINLIRKILTKDFTCCDNEIEICTGYES
TENVHLRRCIGEMFSELPSNCILSSILKAQHLVGDNLTNMEFFEKEGMNAIDGYEKIVQD
YRLGSTALDCSVMITLRKVNCNESFDNEIEKLVNKNHYLRLNVPGRSVQHFAVNVTVVDL
DEKKDALAHYRKYKKQYMESKFAYYEFMKSIQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 2 | g12176.t1 | PANTHER | PTHR14456 | INOSITOL POLYPHOSPHATE KINASE 1 | 29 | 445 | 0 |
| 1 | g12176.t1 | Pfam | PF06090 | Inositol-pentakisphosphate 2-kinase | 31 | 435 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0035299 | inositol pentakisphosphate 2-kinase activity | MF |
| GO:0005524 | ATP binding | MF |
KEGG
Orthology
- This transcript has been annotated with K10572 (inositol-pentakisphosphate 2-kinase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
