General information for g12193.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Scoloptoxin SSD14.
Parent gene
- The parent gene g12193 is located on chr_1: 21679814..21682921 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12193 | g12193.t2 | isoform | g12193.t2 | 21679405 | 21681300 |
| chr_1 | g12193 | g12193.t2 | exon | g12193.t2.exon1 | 21679405 | 21681300 |
| chr_1 | g12193 | g12193.t2 | cds | g12193.t2.CDS1 | 21679814 | 21681184 |
| chr_1 | g12193 | g12193.t2 | TSS | g12193.t2 | NA | NA |
| chr_1 | g12193 | g12193.t2 | TTS | g12193.t2 | NA | NA |
Sequences
>g12193.t2 Gene=g12193 Length=1896
GTCCGCAGTCAACTGGGCTAGGTGGTGGTTTTCATTTGACAATTTACATTAAGAGCAAAA
ATTTAGTCGAATGTCTCGATGCTCGTGAAACTGCACCTAAAAATTCCCACCAACAAATGT
TTGTTAATGATACGAAAAAATCGTCACTCGAAGGTGGTTTATCAATCGCAGTCCCAGGAG
AACTTAAAGGAATGTGGGAATTGCATCAACGCTATGGTAAACTTCCTTGGAAAGACCTTT
TCAAACCAGTGATTGATTTATGTCAGAATGGACATGAAGTAACTGAATATTTGGCACGAG
TTTTGAGTAAAAAGAGTGAAGACATCAAAAACATTCCATCGCTTCGAGAAGTATTTGTCA
ATCCACAAACGGGAGAATTATGGAAAGCAGGAGATAAAATTAAAAGATTAGCATTAGCAA
AAACACTTGAGACAATTGCAAATGAAGGTGCTGATACAATGTATAGTAAAAATGGAACTA
TTGGTCGCCAAATTTTAGAGGACATCAAGGAATTTGGTGGAATTTTAACAGAAGAAGATT
TTACTAATTATAAAGTGAAATGGTTAAAACCAGCTGAAACAACTTTGAAAAATGGCGAGC
GTCTTTATTCTATGCCTTTATCAGGTTCAGGTGCACTTTTAATTTTCATTATGAATTTAT
TAAAACCTTATGATTTAAAAAATGATGTTTTGTCGAACCATCGTATAATTGAAGCTTATA
AATTGGCATATGCTCGACGATCAGAACTTGCAGATCCTGCATTTGTCGAAAGTGCTGAAA
TTTTGATTAGAAATTTAACCAACATTGACTATGCTAATGTAATGAGAAAGAAAATTGATG
ATACAAGAACACACAATGATATTAATTATTATGAAGGACATTTTATATCACAAGAAGACC
ATGGAACTGCTCATATTAGCATTCTTGCACCCAATGGTGATGCAATTTCAGTTACTGGAA
CAATAAACTATATTTTGGGTTCAATGAGAAGAAGTAAAACTGGAATTATTTTAAATGATG
AAATGGATGATTTTAGTACACCTGGTCAAAAGAACATTTATGGCATTTCACCTTCAGAAG
CAAATTACATTCAACCAGGAAAGCGACCAATGTCTTCAATGGCTCCATCGATTGTTGTTA
ATAATGATGGAAATGTCGGATTAATAATTGGAAGTGCTGGAGGCTCTCGAATAACAACTG
CTATCGCTCACACAATCATTCAATATTATTTCCTAAAATCAAAAGATTCACTTTGGAATA
CTTTTTCAATGAAACGACTTCATCATCAATTATTGCCTAATAAAATTTACTTTGAAGATG
GGTTTGATGAGCAAATAATTAATCAATTGAACAAAACATTTAATCATGACGTTGAAAGAG
TTATAGAGCCTATAGGCTTTGGGGCGCTTGTGGGCATTTATGCTGACAATGAATCAGTTC
AAGGAGCTTACGATCCAAGAAGAGGTGGAAGTTCTGTGGTTTTTTAAAATAGATTTTTTT
AAATCGATTTGTCATTGTGATATTTGTTCAACACATTTCTTCTTTACAGTCACTAAAAAG
CATTAAAAGCATTATCAATTTTTAAAGTAAGTTAAAACGAATAGAATTACTTAGACTACG
ACATTTGTATTTTTGATAATTGGCAAAAGTGAATAACTGTAATGATTGACCTTAATAAAA
GATTTTAAAACAAAAAAATATTTTTTATTATTTCTGTCACTATTTCAGAGCAAATGTTAA
TCCCATCGATAAGAATAAAAAGGTAACTTTTTAATGTGATCATTGTAAATTAATGGCACA
ACCTTAAATTTAATAAAGTTATTAAGAAAATAATGAAATTATCAATAATAAATAACAACA
GTCTACATAAATTAATGTTTCCAACTCAATAATTTT
>g12193.t2 Gene=g12193 Length=456
MFVNDTKKSSLEGGLSIAVPGELKGMWELHQRYGKLPWKDLFKPVIDLCQNGHEVTEYLA
RVLSKKSEDIKNIPSLREVFVNPQTGELWKAGDKIKRLALAKTLETIANEGADTMYSKNG
TIGRQILEDIKEFGGILTEEDFTNYKVKWLKPAETTLKNGERLYSMPLSGSGALLIFIMN
LLKPYDLKNDVLSNHRIIEAYKLAYARRSELADPAFVESAEILIRNLTNIDYANVMRKKI
DDTRTHNDINYYEGHFISQEDHGTAHISILAPNGDAISVTGTINYILGSMRRSKTGIILN
DEMDDFSTPGQKNIYGISPSEANYIQPGKRPMSSMAPSIVVNNDGNVGLIIGSAGGSRIT
TAIAHTIIQYYFLKSKDSLWNTFSMKRLHHQLLPNKIYFEDGFDEQIINQLNKTFNHDVE
RVIEPIGFGALVGIYADNESVQGAYDPRRGGSSVVF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g12193.t2 | Gene3D | G3DSA:1.10.246.130 | - | 152 | 257 | 0 |
| 13 | g12193.t2 | Gene3D | G3DSA:3.60.20.40 | - | 258 | 456 | 0 |
| 2 | g12193.t2 | PANTHER | PTHR11686 | GAMMA GLUTAMYL TRANSPEPTIDASE | 1 | 453 | 0 |
| 3 | g12193.t2 | PANTHER | PTHR11686:SF51 | GAMMA-GLUTAMYL TRANSPEPTIDASE, ISOFORM A | 1 | 453 | 0 |
| 7 | g12193.t2 | PRINTS | PR01210 | Gamma-glutamyltranspeptidase signature | 16 | 34 | 0 |
| 10 | g12193.t2 | PRINTS | PR01210 | Gamma-glutamyltranspeptidase signature | 34 | 53 | 0 |
| 9 | g12193.t2 | PRINTS | PR01210 | Gamma-glutamyltranspeptidase signature | 136 | 152 | 0 |
| 4 | g12193.t2 | PRINTS | PR01210 | Gamma-glutamyltranspeptidase signature | 166 | 185 | 0 |
| 6 | g12193.t2 | PRINTS | PR01210 | Gamma-glutamyltranspeptidase signature | 264 | 282 | 0 |
| 11 | g12193.t2 | PRINTS | PR01210 | Gamma-glutamyltranspeptidase signature | 287 | 305 | 0 |
| 5 | g12193.t2 | PRINTS | PR01210 | Gamma-glutamyltranspeptidase signature | 327 | 342 | 0 |
| 8 | g12193.t2 | PRINTS | PR01210 | Gamma-glutamyltranspeptidase signature | 352 | 369 | 0 |
| 1 | g12193.t2 | Pfam | PF01019 | Gamma-glutamyltranspeptidase | 4 | 451 | 0 |
| 12 | g12193.t2 | SUPERFAMILY | SSF56235 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 8 | 455 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006751 | glutathione catabolic process | BP |
| GO:0036374 | glutathione hydrolase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
