General information for g12196.t7
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Probable isoaspartyl peptidase/L-asparaginase CG7860.
Parent gene
- The parent gene g12196 is located on chr_1: 21687824..21696078 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12196 | g12196.t7 | TSS | g12196.t7 | 21686372 | 21686372 |
| chr_1 | g12196 | g12196.t7 | isoform | g12196.t7 | 21686441 | 21687876 |
| chr_1 | g12196 | g12196.t7 | exon | g12196.t7.exon1 | 21686441 | 21687029 |
| chr_1 | g12196 | g12196.t7 | cds | g12196.t7.CDS1 | 21686670 | 21687029 |
| chr_1 | g12196 | g12196.t7 | exon | g12196.t7.exon2 | 21687085 | 21687202 |
| chr_1 | g12196 | g12196.t7 | cds | g12196.t7.CDS2 | 21687085 | 21687202 |
| chr_1 | g12196 | g12196.t7 | exon | g12196.t7.exon3 | 21687367 | 21687602 |
| chr_1 | g12196 | g12196.t7 | cds | g12196.t7.CDS3 | 21687367 | 21687602 |
| chr_1 | g12196 | g12196.t7 | exon | g12196.t7.exon4 | 21687666 | 21687737 |
| chr_1 | g12196 | g12196.t7 | cds | g12196.t7.CDS4 | 21687666 | 21687737 |
| chr_1 | g12196 | g12196.t7 | exon | g12196.t7.exon5 | 21687826 | 21687876 |
| chr_1 | g12196 | g12196.t7 | cds | g12196.t7.CDS5 | 21687826 | 21687876 |
| chr_1 | g12196 | g12196.t7 | TTS | g12196.t7 | 21687955 | 21687955 |
Sequences
>g12196.t7 Gene=g12196 Length=1066
ATGTCAAAAGAGCCCATACCCATTTGCTTGGTTCATGGTGGTGCTGGTTAGTAACATGTT
TTTAAATTCATAATAAATAAACGTAAGAGGATAAATTTTTTCAGGTGATATTCCTGCTAG
TCGAGTTCAAGCAAAATTGAATGGAGTAAAGCAAGCTGCTCAGATCGGATATCATCATCT
TATAAACAATGGCAGTGCTCTGGAAGCAGTAGAATTAGCAGTTATTCATATGGAACTTGA
TCCTGTTTTTAATGCTGGTTATGGAAGTGTACTAACAACTGAAGGTACGGTTGAAATGGA
AGCTTCAGTAATGGATGGAAAAACTTTAAAAGTCGGATGTGTCACTGGTGTTGTGGATAT
TATGCATCCTATTTCAGCTGCTATTCGTGTTATGGAGAAAACTCCACACAACTTTTTAGG
CTTTCATGGAGCAAATAGATTTATAAAACAGCAAGAATTTGAACTTCTTAAGCCTGGAGC
ATTGATAACAGATCAAGCAAAAGAAGCACTTGAACATTGGAAAGAGCAACAAAAAAATGG
TGGATTTAAAGGTTTTGCAAAAACTGAAATTGGTCATAATCAGCATGAAAGAGGTGAGAC
GATTGGAGCTGTTGCGATCGATATTTTGGGAAACATTGCAGTTGCTACATCAACTGGTGG
AATTACTGGAAAATTACCGGGTCGTATTGGTGATACACCTTTGCTGGGTACTTATTGTGA
TAATAGATTTGGAGGGGTTTCAACTACAGGCCATGGAGAAACAATCATGAAAAGCTGCTT
AGCTCATGATATCATAAAACGTATTGACTATCTTGGTGAAGATGCTCAAACTGCAACTGA
AACAGCATGCAACAATATGACTGAGAGGTTTTTCGGGAAAGGTGGAGCAATTACTATCGA
CAAAGACGGTAATGTTGGAATTTCATTTACATCTAAAAGAATGGCCTGGGCTTATCAAAA
ATTAAACACAATGCATTATGGCATCGAAAAGGATGATCATTTTGAACAGATTGTGGATCA
AAATGAAGTTGACTCATTAGTCAATGTAGCTGGAAAATCTTCCTAA
>g12196.t7 Gene=g12196 Length=278
MELDPVFNAGYGSVLTTEGTVEMEASVMDGKTLKVGCVTGVVDIMHPISAAIRVMEKTPH
NFLGFHGANRFIKQQEFELLKPGALITDQAKEALEHWKEQQKNGGFKGFAKTEIGHNQHE
RGETIGAVAIDILGNIAVATSTGGITGKLPGRIGDTPLLGTYCDNRFGGVSTTGHGETIM
KSCLAHDIIKRIDYLGEDAQTATETACNNMTERFFGKGGAITIDKDGNVGISFTSKRMAW
AYQKLNTMHYGIEKDDHFEQIVDQNEVDSLVNVAGKSS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g12196.t7 | CDD | cd04702 | ASRGL1_like | 1 | 244 | 0 |
| 5 | g12196.t7 | Gene3D | G3DSA:3.60.20.30 | (Glycosyl)asparaginase | 124 | 262 | 0 |
| 2 | g12196.t7 | PANTHER | PTHR10188 | L-ASPARAGINASE | 1 | 256 | 0 |
| 3 | g12196.t7 | PANTHER | PTHR10188:SF37 | SI:CH211-256M1.8 | 1 | 256 | 0 |
| 1 | g12196.t7 | Pfam | PF01112 | Asparaginase | 1 | 250 | 0 |
| 4 | g12196.t7 | SUPERFAMILY | SSF56235 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | 255 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016787 | hydrolase activity | MF |
| GO:0004067 | asparaginase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
