Gene loci information

Transcript annotation

  • This transcript has been annotated as Probable isoaspartyl peptidase/L-asparaginase CG7860.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g12196 g12196.t8 TSS g12196.t8 21686372 21686372
chr_1 g12196 g12196.t8 isoform g12196.t8 21686441 21687876
chr_1 g12196 g12196.t8 exon g12196.t8.exon1 21686441 21687029
chr_1 g12196 g12196.t8 cds g12196.t8.CDS1 21686670 21687029
chr_1 g12196 g12196.t8 exon g12196.t8.exon2 21687085 21687205
chr_1 g12196 g12196.t8 cds g12196.t8.CDS2 21687085 21687205
chr_1 g12196 g12196.t8 exon g12196.t8.exon3 21687367 21687602
chr_1 g12196 g12196.t8 cds g12196.t8.CDS3 21687367 21687602
chr_1 g12196 g12196.t8 exon g12196.t8.exon4 21687666 21687737
chr_1 g12196 g12196.t8 cds g12196.t8.CDS4 21687666 21687737
chr_1 g12196 g12196.t8 exon g12196.t8.exon5 21687826 21687876
chr_1 g12196 g12196.t8 cds g12196.t8.CDS5 21687826 21687876
chr_1 g12196 g12196.t8 TTS g12196.t8 21687955 21687955

Sequences

>g12196.t8 Gene=g12196 Length=1069
ATGTCAAAAGAGCCCATACCCATTTGCTTGGTTCATGGTGGTGCTGGTTAGTAACATGTT
TTTAAATTCATAATAAATAAACGTAAGAGGATAAATTTTTTCAGGTGATATTCCTGCTAG
TCGAGTTCAAGCAAAATTGAATGGAGTAAAGCAAGCTGCTCAGATCGGATATCATCATCT
TATAAACAATGGCAGTGCTCTGGAAGCAGTAGAATTAGCAGTTATTCATATGGAACTTGA
TCCTGTTTTTAATGCTGGTTATGGAAGTGTACTAACAACTGAAGGTACGGTTGAAATGGA
AGCTTCAGTAATGGATGGAAAAACTTTAAAAGTCGGATGTGTCACTGGTGTTGTGGATAT
TATGCATCCTATTTCAGCTGCTATTCGTGTTATGGAGAAAACTCCACACAACTTTTTAGG
CTTTCATGGAGCAAATAGATTTATAAAACAGCAAGAATTTGAACTTCTTAAGCCTGGAGC
ATTGATAACAGATCAAGCAAAAGAAGCACTTGAACATTGGAAAGAGCAACAAAAAAATGG
TGGATTTAAAGGTTTTGCAAAAACTGAAATTGGTCATAATCAGCATGAAAGAGGTGAGAC
GATTGGAGCTGTTGCGATCGATATTTTGGGAAACATTGCAGTTGCTACATCAACTGGTGG
AATTACTGGAAAATTACCGGGTCGTATTGGTGATACACCTTTGCTGGGTTGTACTTATTG
TGATAATAGATTTGGAGGGGTTTCAACTACAGGCCATGGAGAAACAATCATGAAAAGCTG
CTTAGCTCATGATATCATAAAACGTATTGACTATCTTGGTGAAGATGCTCAAACTGCAAC
TGAAACAGCATGCAACAATATGACTGAGAGGTTTTTCGGGAAAGGTGGAGCAATTACTAT
CGACAAAGACGGTAATGTTGGAATTTCATTTACATCTAAAAGAATGGCCTGGGCTTATCA
AAAATTAAACACAATGCATTATGGCATCGAAAAGGATGATCATTTTGAACAGATTGTGGA
TCAAAATGAAGTTGACTCATTAGTCAATGTAGCTGGAAAATCTTCCTAA

>g12196.t8 Gene=g12196 Length=279
MELDPVFNAGYGSVLTTEGTVEMEASVMDGKTLKVGCVTGVVDIMHPISAAIRVMEKTPH
NFLGFHGANRFIKQQEFELLKPGALITDQAKEALEHWKEQQKNGGFKGFAKTEIGHNQHE
RGETIGAVAIDILGNIAVATSTGGITGKLPGRIGDTPLLGCTYCDNRFGGVSTTGHGETI
MKSCLAHDIIKRIDYLGEDAQTATETACNNMTERFFGKGGAITIDKDGNVGISFTSKRMA
WAYQKLNTMHYGIEKDDHFEQIVDQNEVDSLVNVAGKSS

Protein features from InterProScan

Transcript Database ID Name Start End E.value
6 g12196.t8 CDD cd04702 ASRGL1_like 1 245 0
5 g12196.t8 Gene3D G3DSA:3.60.20.30 (Glycosyl)asparaginase 124 263 0
2 g12196.t8 PANTHER PTHR10188 L-ASPARAGINASE 1 257 0
3 g12196.t8 PANTHER PTHR10188:SF37 SI:CH211-256M1.8 1 257 0
1 g12196.t8 Pfam PF01112 Asparaginase 1 251 0
4 g12196.t8 SUPERFAMILY SSF56235 N-terminal nucleophile aminohydrolases (Ntn hydrolases) 1 256 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016787 hydrolase activity MF
GO:0004067 asparaginase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed