General information for g12267.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Nicotinate phosphoribosyltransferase.
Parent gene
- The parent gene g12267 is located on chr_1: 22090633..22091581 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12267 | g12267.t2 | TSS | g12267.t2 | 22086345 | 22086345 |
| chr_1 | g12267 | g12267.t2 | isoform | g12267.t2 | 22086570 | 22087602 |
| chr_1 | g12267 | g12267.t2 | exon | g12267.t2.exon1 | 22086570 | 22086675 |
| chr_1 | g12267 | g12267.t2 | cds | g12267.t2.CDS1 | 22086570 | 22086675 |
| chr_1 | g12267 | g12267.t2 | exon | g12267.t2.exon2 | 22086737 | 22086757 |
| chr_1 | g12267 | g12267.t2 | cds | g12267.t2.CDS2 | 22086737 | 22086757 |
| chr_1 | g12267 | g12267.t2 | exon | g12267.t2.exon3 | 22087093 | 22087602 |
| chr_1 | g12267 | g12267.t2 | cds | g12267.t2.CDS3 | 22087093 | 22087601 |
| chr_1 | g12267 | g12267.t2 | TTS | g12267.t2 | NA | NA |
Sequences
>g12267.t2 Gene=g12267 Length=637
ATGACAACCACATGTGAGGATAATGAGATGAATAATTCAGGAATGGATGCATTTTCCATT
CAAAATTATCGCCGTGATTCAACTCATTGTTTTTATCAAAATAGAGTAATTCAACCATTG
TTAACAGATCTTTATCAGATAACGATGGCGTATGCTTATTGGAAATCAGGCAAAATAGAA
GATCAAGCTGTATTTGATTTGTTCTTCCGAAAAAATCCATTTCATGGCGAATTTACTATT
TTTTGTGGCCTAGAGGAATGTTTGAAATTTATTAAAAATTTCCATTATTCAGCGGGTGAT
ATCAATTATCTCAAGTCTGTTTTGCCTGAAGGGATTGAGGAGGAATTTTTCGAGTATTTG
GGAAAGTTGACTGCAAAAGACGTTACACTTTATGCTCTCGATGAAGGATCAGTTACATTT
CCTCGTATTCCATTGATGAGACTTGAAGGTCCTTTAATTATTGTACAACTACTCGAAACA
ACACTCTTGACACTTGTCAATTATGCAAGTCTTATGGCTACTAATGCTGCTCGATACAGA
ATTGTAGCTGGACCAGTAGCGAAACTATTAGAATTTGGTTTGCGACGTGCTCAAGGTCCC
GATGGAGGACTTTCTTCTTCAAAATATGCATACATTG
>g12267.t2 Gene=g12267 Length=212
MTTTCEDNEMNNSGMDAFSIQNYRRDSTHCFYQNRVIQPLLTDLYQITMAYAYWKSGKIE
DQAVFDLFFRKNPFHGEFTIFCGLEECLKFIKNFHYSAGDINYLKSVLPEGIEEEFFEYL
GKLTAKDVTLYALDEGSVTFPRIPLMRLEGPLIIVQLLETTLLTLVNYASLMATNAARYR
IVAGPVAKLLEFGLRRAQGPDGGLSSSKYAYI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g12267.t2 | Gene3D | G3DSA:3.20.140.10 | nicotinate phosphoribosyltransferase | 28 | 193 | 0.0e+00 |
| 2 | g12267.t2 | PANTHER | PTHR11098 | NICOTINATE PHOSPHORIBOSYLTRANSFERASE | 32 | 212 | 0.0e+00 |
| 1 | g12267.t2 | Pfam | PF17767 | Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain | 40 | 167 | 0.0e+00 |
| 4 | g12267.t2 | SUPERFAMILY | SSF54675 | Nicotinate/Quinolinate PRTase N-terminal domain-like | 28 | 177 | 0.0e+00 |
| 3 | g12267.t2 | SUPERFAMILY | SSF51690 | Nicotinate/Quinolinate PRTase C-terminal domain-like | 173 | 212 | 1.2e-06 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity | MF |
| GO:0009435 | NAD biosynthetic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
