General information for g12267.t7
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Nicotinate phosphoribosyltransferase.
Parent gene
- The parent gene g12267 is located on chr_1: 22090633..22091581 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12267 | g12267.t7 | isoform | g12267.t7 | 22088738 | 22091581 |
| chr_1 | g12267 | g12267.t7 | exon | g12267.t7.exon1 | 22088738 | 22088900 |
| chr_1 | g12267 | g12267.t7 | cds | g12267.t7.CDS1 | 22088833 | 22088900 |
| chr_1 | g12267 | g12267.t7 | exon | g12267.t7.exon2 | 22090053 | 22090306 |
| chr_1 | g12267 | g12267.t7 | cds | g12267.t7.CDS2 | 22090053 | 22090306 |
| chr_1 | g12267 | g12267.t7 | exon | g12267.t7.exon3 | 22090367 | 22090640 |
| chr_1 | g12267 | g12267.t7 | cds | g12267.t7.CDS3 | 22090367 | 22090640 |
| chr_1 | g12267 | g12267.t7 | exon | g12267.t7.exon4 | 22090706 | 22090853 |
| chr_1 | g12267 | g12267.t7 | cds | g12267.t7.CDS4 | 22090706 | 22090853 |
| chr_1 | g12267 | g12267.t7 | exon | g12267.t7.exon5 | 22090916 | 22091581 |
| chr_1 | g12267 | g12267.t7 | cds | g12267.t7.CDS5 | 22090916 | 22090993 |
| chr_1 | g12267 | g12267.t7 | TTS | g12267.t7 | 22091578 | 22091578 |
| chr_1 | g12267 | g12267.t7 | TSS | g12267.t7 | NA | NA |
Sequences
>g12267.t7 Gene=g12267 Length=1505
CTGATTTGCTTGAGCTCTCTATTGAACATCGAAAAAATTTATCGAGTGTGCTGCATATAA
GTACACAAGAGGCAAACGATGGTGAATTGGCGGCCATGGTGTCATTTGCAATTGCATTTC
CCGATGGATTCATGGCTCTCGTCGACACGTACGATGTTAAACGGAGTGGACTTTTGAATT
TTTGTGCTGTTGCATTATCATTGAATGATCAAGGTTATCGTCCCGTTGGTATCCGAATAG
ATTCTGGTGATTTGGCATATCTCTCATGTTTAGCGCGGCAAAATTTCATCACAATCAGTG
AATATTACGGTTTGCCATGGTTTGCTGAATTAACTATTGTCGCATCAAATGATATCAATG
AAGAAACTATTTTAAGTTTAAATGAACAAGGTCACAAGATTGATTGTTTTGGAATTGGTA
CTCATTTGGTAACATGTCAAAAGCAGCCTGCATTGGGATGCGTTTACAAACTTGTTGAGA
TCAATAATCAACCGCGAATAAAATTGAGTCAAGATGCTGAAAAAATAACTATGCCTGGGA
AAAAGAATGTTTTCCGATTGTATGGAACTGAAGGATGGGCTGTGATTGATATTCTGCAAA
AAGACGATGAAGATCCGCCTGAACCTGGAAAAAAAGTTTTATGTCGTCATCCTTTCCATG
AATCTAAACGAGCATTTGTAACACCTGCAAGAGTTGAAACTTTATATAAAATTTGGTGGA
AAGACGGTGCGATACGTCAACCAATACCAAGTTTGGAGGAAGTTAGAAATCGCGTACAGG
AATCTTTGGGAACTTTACGTCAAGATCATTTAAGACATTTGAATCCTACTCCGTACAAAG
TTGCTGTAAGTGATAATCTCTACAATTTTCTCCATGATTTGTGGTTATTAAATCAACCTA
TCGGGGAACTCTCGTGATAAAACTGAAGCCCCGCATCATTCATCTTCATTCTAACTTACC
GCATTATGTTCAGCACATAATTTTAATTTTATGTACTAATTAGCCATCATTCACAATAAA
TAATTGGAGTGATTGTGCAGTTTTTATTGAAATTTTTAAATTTCACTTCATTTTATTAGC
CTGACTCACTTTTATCTCTTTCCTCCTCTGTCAGTCACACATCAGAAACATTCAAAATAT
AAACCATAAAAGACATGAGAAAATAGTTCAAAAAATTATCAAAAAAAACATGAGTATGCA
CTATTTTGCAAATAGACATTTACTTAATAGTAAAATAAAATATAAAAAGGGAAAAAATAA
TTTGTAGCACACTTTTGCACTTTTATTATAACTCATGTACCTATCTTTTGTCAATAATAA
AAAAAAATTAAAATTGAAAAAAGCATCATGTTGGGACAGAATTAAAGTCAGGTGCCTTAA
AAATAATTAGAGCTTTTTTATAATTTCCATTCATTTATCTACAATAGAAAGTTGAGTAGA
AATATAAAATAGTCATTAATTGTTAGAAATGAAAGTTATGTAATAAAATCAGCTTTAATG
TTAAA
>g12267.t7 Gene=g12267 Length=273
MVSFAIAFPDGFMALVDTYDVKRSGLLNFCAVALSLNDQGYRPVGIRIDSGDLAYLSCLA
RQNFITISEYYGLPWFAELTIVASNDINEETILSLNEQGHKIDCFGIGTHLVTCQKQPAL
GCVYKLVEINNQPRIKLSQDAEKITMPGKKNVFRLYGTEGWAVIDILQKDDEDPPEPGKK
VLCRHPFHESKRAFVTPARVETLYKIWWKDGAIRQPIPSLEEVRNRVQESLGTLRQDHLR
HLNPTPYKVAVSDNLYNFLHDLWLLNQPIGELS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g12267.t7 | Gene3D | G3DSA:3.20.140.10 | nicotinate phosphoribosyltransferase | 83 | 268 | 0.0e+00 |
| 3 | g12267.t7 | PANTHER | PTHR11098:SF22 | NICOTINATE PHOSPHORIBOSYLTRANSFERASE 2-LIKE | 2 | 272 | 0.0e+00 |
| 4 | g12267.t7 | PANTHER | PTHR11098 | NICOTINATE PHOSPHORIBOSYLTRANSFERASE | 2 | 272 | 0.0e+00 |
| 2 | g12267.t7 | Pfam | PF04095 | Nicotinate phosphoribosyltransferase (NAPRTase) family | 43 | 145 | 2.2e-05 |
| 1 | g12267.t7 | Pfam | PF17956 | Nicotinate phosphoribosyltransferase C-terminal domain | 149 | 258 | 0.0e+00 |
| 5 | g12267.t7 | SUPERFAMILY | SSF51690 | Nicotinate/Quinolinate PRTase C-terminal domain-like | 2 | 268 | 0.0e+00 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity | MF |
| GO:0009435 | NAD biosynthetic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
