General information for g12339.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Annexin B11.
Parent gene
- The parent gene g12339 is located on chr_1: 22640276..22641588 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12339 | g12339.t3 | TSS | g12339.t3 | 22638900 | 22638900 |
| chr_1 | g12339 | g12339.t3 | isoform | g12339.t3 | 22639743 | 22641216 |
| chr_1 | g12339 | g12339.t3 | exon | g12339.t3.exon1 | 22639743 | 22639754 |
| chr_1 | g12339 | g12339.t3 | cds | g12339.t3.CDS1 | 22639743 | 22639754 |
| chr_1 | g12339 | g12339.t3 | exon | g12339.t3.exon2 | 22640194 | 22640881 |
| chr_1 | g12339 | g12339.t3 | cds | g12339.t3.CDS2 | 22640194 | 22640881 |
| chr_1 | g12339 | g12339.t3 | exon | g12339.t3.exon3 | 22640939 | 22641216 |
| chr_1 | g12339 | g12339.t3 | cds | g12339.t3.CDS3 | 22640939 | 22641216 |
| chr_1 | g12339 | g12339.t3 | TTS | g12339.t3 | 22641592 | 22641592 |
Sequences
>g12339.t3 Gene=g12339 Length=978
ATGTTTCCATTCGGTACTCCTACTGTTCTACCAAAAGAAAACTTTGATGCTCATGCTGAT
TCTGCAGCTTTACGAAAAGCAATGAAGGGCTGGGGTTGCAATGACGAAGAGTTAATTGAA
ATTTTATGTCGTCGCAGCAATGATCAACGTCAACAGATTCAAAAAGTATTCAAAACGGAT
TATGGAAAGGATTTGATTGAAAATATCAAGAGTGAAACTCGTGGCAACTTTGAAGATTTA
CTGGTAGCATTGCTCACACCAACATTGGATTTTTACTGCAAAGAGATTTATGATGCATGC
GCTGGAATTGGTACAGATGAAGACGCTTTGGTTGAGGTCTTTTGCACACTCTCAAATAAC
GAGATTACCATGATTAGAGATCGTTATCGTGAGCTTTATGGAAAGGATTTGGAAAATGTT
TTAATTGGTGAAACATCGGGAAATTTCAAGCGTTTACTTGTTTCTCTTGTGAATGCAAAT
CGTGACGAATCTGGAATTACTGATATTGAGAAAGCTAAAGCTGATGCTACTGCTTTATTG
CGTGCTGGTGAGCTTCGTGCGGGAACTGACGAATCAACATTCAATTCTATCTTGTGCCAA
CGCAATTATCAACAATTGAAATTAATTTTCGATGAATATGAAAAGATGACTGGCCATAGC
TTTGCAAAAGCAATTGAAAATGAATTTTCCGGTACAGAGAGTGACATCAAAGATGGTTTT
CTTGCCATATTCCAAGTTATTACTAACAAACACGAATTCTTTGCTCGTCGTTTGCACAAA
TCAATGGCTGGTTTAGGCACTACAGACAAACAACTCATTCGTTTGGTTGTTACACGCTGT
GAAATTGACATGGGCGAAATCAAAGAAGCTTTCCAGCGACTTTTTGGCGAATCTTTACGT
GACATGATTAAAGGTGATACCTCAGGTTCTTATAAGCACGCATTGTATGCTTTAATTGGA
GAACAACGAAGCTCTTAA
>g12339.t3 Gene=g12339 Length=325
MFPFGTPTVLPKENFDAHADSAALRKAMKGWGCNDEELIEILCRRSNDQRQQIQKVFKTD
YGKDLIENIKSETRGNFEDLLVALLTPTLDFYCKEIYDACAGIGTDEDALVEVFCTLSNN
EITMIRDRYRELYGKDLENVLIGETSGNFKRLLVSLVNANRDESGITDIEKAKADATALL
RAGELRAGTDESTFNSILCQRNYQQLKLIFDEYEKMTGHSFAKAIENEFSGTESDIKDGF
LAIFQVITNKHEFFARRLHKSMAGLGTTDKQLIRLVVTRCEIDMGEIKEAFQRLFGESLR
DMIKGDTSGSYKHALYALIGEQRSS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g12339.t3 | Gene3D | G3DSA:1.10.220.10 | - | 14 | 86 | 3.7E-29 |
| 17 | g12339.t3 | Gene3D | G3DSA:1.10.220.10 | - | 89 | 162 | 3.5E-23 |
| 15 | g12339.t3 | Gene3D | G3DSA:1.10.220.10 | - | 163 | 249 | 6.6E-25 |
| 14 | g12339.t3 | Gene3D | G3DSA:1.10.220.10 | - | 251 | 321 | 3.1E-25 |
| 5 | g12339.t3 | PANTHER | PTHR10502 | ANNEXIN | 7 | 320 | 7.4E-129 |
| 6 | g12339.t3 | PANTHER | PTHR10502:SF226 | ANNEXIN | 7 | 320 | 7.4E-129 |
| 8 | g12339.t3 | PRINTS | PR00196 | Annexin family signature | 29 | 51 | 8.9E-46 |
| 7 | g12339.t3 | PRINTS | PR00196 | Annexin family signature | 69 | 85 | 8.9E-46 |
| 12 | g12339.t3 | PRINTS | PR00196 | Annexin family signature | 96 | 117 | 8.9E-46 |
| 9 | g12339.t3 | PRINTS | PR00196 | Annexin family signature | 179 | 205 | 8.9E-46 |
| 11 | g12339.t3 | PRINTS | PR00196 | Annexin family signature | 262 | 282 | 8.9E-46 |
| 10 | g12339.t3 | PRINTS | PR00196 | Annexin family signature | 306 | 319 | 8.9E-46 |
| 1 | g12339.t3 | Pfam | PF00191 | Annexin | 20 | 84 | 1.8E-25 |
| 4 | g12339.t3 | Pfam | PF00191 | Annexin | 94 | 156 | 6.8E-19 |
| 2 | g12339.t3 | Pfam | PF00191 | Annexin | 175 | 242 | 6.1E-19 |
| 3 | g12339.t3 | Pfam | PF00191 | Annexin | 253 | 318 | 1.5E-19 |
| 18 | g12339.t3 | ProSitePatterns | PS00223 | Annexin repeat signature. | 266 | 318 | - |
| 25 | g12339.t3 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 15 | 86 | 29.311 |
| 24 | g12339.t3 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 87 | 158 | 23.3 |
| 23 | g12339.t3 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 170 | 245 | 21.168 |
| 26 | g12339.t3 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 249 | 320 | 24.772 |
| 20 | g12339.t3 | SMART | SM00335 | annex3 | 32 | 84 | 2.5E-22 |
| 22 | g12339.t3 | SMART | SM00335 | annex3 | 104 | 156 | 2.7E-19 |
| 19 | g12339.t3 | SMART | SM00335 | annex3 | 188 | 243 | 1.6E-13 |
| 21 | g12339.t3 | SMART | SM00335 | annex3 | 266 | 318 | 1.7E-18 |
| 13 | g12339.t3 | SUPERFAMILY | SSF47874 | Annexin | 4 | 320 | 3.4E-113 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005544 | calcium-dependent phospholipid binding | MF |
| GO:0005509 | calcium ion binding | MF |
KEGG
Orthology
- This transcript has been annotated with K17095 (annexin A7/11)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
