General information for g12339.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Annexin B11.
Parent gene
- The parent gene g12339 is located on chr_1: 22640276..22641588 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12339 | g12339.t8 | isoform | g12339.t8 | 22640276 | 22641588 |
| chr_1 | g12339 | g12339.t8 | exon | g12339.t8.exon1 | 22640276 | 22640881 |
| chr_1 | g12339 | g12339.t8 | cds | g12339.t8.CDS1 | 22640551 | 22640881 |
| chr_1 | g12339 | g12339.t8 | exon | g12339.t8.exon2 | 22640939 | 22641588 |
| chr_1 | g12339 | g12339.t8 | cds | g12339.t8.CDS2 | 22640939 | 22641216 |
| chr_1 | g12339 | g12339.t8 | TTS | g12339.t8 | 22641592 | 22641592 |
| chr_1 | g12339 | g12339.t8 | TSS | g12339.t8 | NA | NA |
Sequences
>g12339.t8 Gene=g12339 Length=1256
GTTGCAATGACGAAGAGTTAATTGAAATTTTATGTCGTCGCAGCAATGATCAACGTCAAC
AGATTCAAAAAGTATTCAAAACGGATTATGGAAAGGATTTGATTGAAAATATCAAGAGTG
AAACTCGTGGCAACTTTGAAGATTTACTGGTAGCATTGCTCACACCAACATTGGATTTTT
ACTGCAAAGAGATTTATGATGCATGCGCTGGAATTGGTACAGATGAAGACGCTTTGGTTG
AGGTCTTTTGCACACTCTCAAATAACGAGATTACCATGATTAGAGATCGTTATCGTGAGC
TTTATGGAAAGGATTTGGAAAATGTTTTAATTGGTGAAACATCGGGAAATTTCAAGCGTT
TACTTGTTTCTCTTGTGAATGCAAATCGTGACGAATCTGGAATTACTGATATTGAGAAAG
CTAAAGCTGATGCTACTGCTTTATTGCGTGCTGGTGAGCTTCGTGCGGGAACTGACGAAT
CAACATTCAATTCTATCTTGTGCCAACGCAATTATCAACAATTGAAATTAATTTTCGATG
AATATGAAAAGATGACTGGCCATAGCTTTGCAAAAGCAATTGAAAATGAATTTTCCGGTA
CAGAGAGTGACATCAAAGATGGTTTTCTTGCCATATTCCAAGTTATTACTAACAAACACG
AATTCTTTGCTCGTCGTTTGCACAAATCAATGGCTGGTTTAGGCACTACAGACAAACAAC
TCATTCGTTTGGTTGTTACACGCTGTGAAATTGACATGGGCGAAATCAAAGAAGCTTTCC
AGCGACTTTTTGGCGAATCTTTACGTGACATGATTAAAGGTGATACCTCAGGTTCTTATA
AGCACGCATTGTATGCTTTAATTGGAGAACAACGAAGCTCTTAATTTCGTACAATTTAAA
TTTACATATTTAAAGTTATTGATAAGATATTTTATTAATTTTTCACTTATTCAAAAACAT
TTTTGTATTCTACATAATTTTACAAACACAATTTTACTCGAATTATTCTCAGCTTTCTGA
AGACATTTTTCTTATAATTTTTAAATTACCATAATAACTAGACCAAATAAAAGTGCTGAT
GAATAATTCACGCTCATAAATTAGCAACTTAATTTTTGTCTATTTCACGCATCATATTTT
ACAAATATTTCTTTGATTTAAGAATCAACTCGTACATTTGTATTTGTCGGATATTAAAAA
TATTATAATATTGAATACATTGATGTGTCAATAAAGTACCTACGAATTTTAATCTA
>g12339.t8 Gene=g12339 Length=202
MIRDRYRELYGKDLENVLIGETSGNFKRLLVSLVNANRDESGITDIEKAKADATALLRAG
ELRAGTDESTFNSILCQRNYQQLKLIFDEYEKMTGHSFAKAIENEFSGTESDIKDGFLAI
FQVITNKHEFFARRLHKSMAGLGTTDKQLIRLVVTRCEIDMGEIKEAFQRLFGESLRDMI
KGDTSGSYKHALYALIGEQRSS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g12339.t8 | Gene3D | G3DSA:1.10.220.10 | - | 1 | 39 | 1.1E-9 |
| 12 | g12339.t8 | Gene3D | G3DSA:1.10.220.10 | - | 40 | 126 | 2.4E-25 |
| 13 | g12339.t8 | Gene3D | G3DSA:1.10.220.10 | - | 128 | 198 | 1.3E-25 |
| 4 | g12339.t8 | PANTHER | PTHR10502 | ANNEXIN | 2 | 197 | 9.6E-79 |
| 5 | g12339.t8 | PANTHER | PTHR10502:SF226 | ANNEXIN | 2 | 197 | 9.6E-79 |
| 2 | g12339.t8 | Pfam | PF00191 | Annexin | 2 | 33 | 9.9E-8 |
| 3 | g12339.t8 | Pfam | PF00191 | Annexin | 52 | 119 | 2.5E-19 |
| 1 | g12339.t8 | Pfam | PF00191 | Annexin | 130 | 195 | 6.3E-20 |
| 10 | g12339.t8 | ProSitePatterns | PS00223 | Annexin repeat signature. | 143 | 195 | - |
| 16 | g12339.t8 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 1 | 35 | 13.501 |
| 14 | g12339.t8 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 47 | 122 | 21.168 |
| 15 | g12339.t8 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 126 | 197 | 24.772 |
| 8 | g12339.t8 | SMART | SM00335 | annex3 | 1 | 33 | 0.016 |
| 7 | g12339.t8 | SMART | SM00335 | annex3 | 65 | 120 | 1.6E-13 |
| 9 | g12339.t8 | SMART | SM00335 | annex3 | 143 | 195 | 1.7E-18 |
| 6 | g12339.t8 | SUPERFAMILY | SSF47874 | Annexin | 2 | 198 | 4.32E-67 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005544 | calcium-dependent phospholipid binding | MF |
| GO:0005509 | calcium ion binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
