Gene loci information

Transcript annotation

  • This transcript has been annotated as Annexin B11.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g12342 g12342.t3 TSS g12342.t3 22645505 22645505
chr_1 g12342 g12342.t3 isoform g12342.t3 22645545 22646804
chr_1 g12342 g12342.t3 exon g12342.t3.exon1 22645545 22645562
chr_1 g12342 g12342.t3 cds g12342.t3.CDS1 22645545 22645562
chr_1 g12342 g12342.t3 exon g12342.t3.exon2 22645632 22646691
chr_1 g12342 g12342.t3 cds g12342.t3.CDS2 22645632 22646691
chr_1 g12342 g12342.t3 exon g12342.t3.exon3 22646758 22646804
chr_1 g12342 g12342.t3 cds g12342.t3.CDS3 22646758 22646804
chr_1 g12342 g12342.t3 TTS g12342.t3 22646882 22646882

Sequences

>g12342.t3 Gene=g12342 Length=1125
ATGTATCCAAATCAAAATCAGCCAGGATATGGGTATCCTCCTCCACAACAAATGCCAATG
GCACAAATAGGTATGCCTTTGCAAATGCATCAACAGCAATTTCCTATGGGCTTTATGCAA
CAACCAATGAGTTATCAACAAATGCCTGGCCAAATGAACATGCGAATGGCTCAACAATTT
TTTGTTAAAAAGACACGTCCAACTGTAAAACCAGTAGAAAATTTTGATGCTTCAGCAGAT
GCTGCAATTTTACGTAAAGCAATGAAAGGAATTGGGACTGATGAAAAAGCTTTGATTTCT
GTAATTTGTTGTCGCCCAAACTATCAATTAATTGAAATTGCAAAAGCTTTCAAGACATCG
TACGGGAAAGATTTAATTGACAATGTTAAATCAGAAACATCTAATAATTTTCAAAAAGTT
TTAATTGCGTTAATTAAACCAAGATGGGAATTTATATGTGAAGAATTGCAGAAAGGTGAT
GCTGAAGCACTTTATGAAATTATGTGCACATTGACAAATGAAGAAATACGTCAGATTAAA
AATGTCTTTCAAATGAAATATAAAAGCGATTTAGAAAGCACATTGAAGAAAAGCACAAGT
GGTTACATGAAACGACTTATGATTTCATTATCATCTGGAGGACGTGATGAATCCATGCAC
ACAGACATTGAAAAAGCACGAACTGACGCACTTGCATTAAAAAAGGCTGGTGTTGATAGG
TTGGGAACAGATGAAGCAGAATTTATTCGTGTTCTCTGTTTGCGTAATTTTGAACAATTA
AAGCTTGTATGTCAAGAATATGAAAAATTGAGAGGAAAATCTTTAGAGAAAGACATTAAA
AGTGAATTTAGTGGAGATATCCAAGATTCTCTTCTTGCAATTGTTCGTTATGCAAATAAT
CAGTCTGCATTTTTTGCAAAATGTTTATACAAGTCTATGAAAGGCATCGGAACAAATGAT
AGTCGATTGATTCGGGTTTGCGTTTTGCGTGCTGAGATCGATATGATGGACATTAAAGAT
GAGTTTTTAAAGATTGAAGGAAAAACATTGAAGAGTTTTATTGAAGGGGATACATCTGGT
GATTATAGAAGAGCTCTTTTGACTTTATGTGGTGAATTATATTAA

>g12342.t3 Gene=g12342 Length=374
MYPNQNQPGYGYPPPQQMPMAQIGMPLQMHQQQFPMGFMQQPMSYQQMPGQMNMRMAQQF
FVKKTRPTVKPVENFDASADAAILRKAMKGIGTDEKALISVICCRPNYQLIEIAKAFKTS
YGKDLIDNVKSETSNNFQKVLIALIKPRWEFICEELQKGDAEALYEIMCTLTNEEIRQIK
NVFQMKYKSDLESTLKKSTSGYMKRLMISLSSGGRDESMHTDIEKARTDALALKKAGVDR
LGTDEAEFIRVLCLRNFEQLKLVCQEYEKLRGKSLEKDIKSEFSGDIQDSLLAIVRYANN
QSAFFAKCLYKSMKGIGTNDSRLIRVCVLRAEIDMMDIKDEFLKIEGKTLKSFIEGDTSG
DYRRALLTLCGELY

Protein features from InterProScan

Transcript Database ID Name Start End E.value
16 g12342.t3 Gene3D G3DSA:1.10.220.10 - 66 145 2.2E-26
15 g12342.t3 Gene3D G3DSA:1.10.220.10 - 154 214 4.1E-14
14 g12342.t3 Gene3D G3DSA:1.10.220.10 - 215 300 6.0E-27
17 g12342.t3 Gene3D G3DSA:1.10.220.10 - 302 373 1.9E-24
5 g12342.t3 PANTHER PTHR10502 ANNEXIN 51 371 8.5E-112
6 g12342.t3 PANTHER PTHR10502:SF226 ANNEXIN 51 371 8.5E-112
7 g12342.t3 PRINTS PR00196 Annexin family signature 89 111 2.3E-36
10 g12342.t3 PRINTS PR00196 Annexin family signature 129 145 2.3E-36
9 g12342.t3 PRINTS PR00196 Annexin family signature 233 259 2.3E-36
11 g12342.t3 PRINTS PR00196 Annexin family signature 313 333 2.3E-36
8 g12342.t3 PRINTS PR00196 Annexin family signature 357 370 2.3E-36
4 g12342.t3 Pfam PF00191 Annexin 80 144 1.1E-23
1 g12342.t3 Pfam PF00191 Annexin 160 210 3.2E-12
3 g12342.t3 Pfam PF00191 Annexin 233 294 2.2E-20
2 g12342.t3 Pfam PF00191 Annexin 304 369 2.2E-18
18 g12342.t3 ProSitePatterns PS00223 Annexin repeat signature. 92 144 -
26 g12342.t3 ProSiteProfiles PS51897 Annexin repeat profile. 75 146 28.237
23 g12342.t3 ProSiteProfiles PS51897 Annexin repeat profile. 147 212 8.441
25 g12342.t3 ProSiteProfiles PS51897 Annexin repeat profile. 224 296 25.914
24 g12342.t3 ProSiteProfiles PS51897 Annexin repeat profile. 300 371 21.184
20 g12342.t3 SMART SM00335 annex3 92 144 2.5E-18
22 g12342.t3 SMART SM00335 annex3 158 210 8.6E-11
19 g12342.t3 SMART SM00335 annex3 242 294 1.4E-20
21 g12342.t3 SMART SM00335 annex3 317 369 7.3E-17
12 g12342.t3 SUPERFAMILY SSF81995 beta-sandwich domain of Sec23/24 2 59 1.99E-6
13 g12342.t3 SUPERFAMILY SSF47874 Annexin 40 371 1.22E-106

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005544 calcium-dependent phospholipid binding MF
GO:0005509 calcium ion binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values