General information for g12343.t10
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Annexin B11.
Parent gene
- The parent gene g12343 is located on chr_1: 22649445..22650065 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12343 | g12343.t10 | TSS | g12343.t10 | 22647505 | 22647505 |
| chr_1 | g12343 | g12343.t10 | isoform | g12343.t10 | 22647634 | 22650065 |
| chr_1 | g12343 | g12343.t10 | exon | g12343.t10.exon1 | 22647634 | 22648284 |
| chr_1 | g12343 | g12343.t10 | cds | g12343.t10.CDS1 | 22647871 | 22648284 |
| chr_1 | g12343 | g12343.t10 | exon | g12343.t10.exon2 | 22648513 | 22648588 |
| chr_1 | g12343 | g12343.t10 | cds | g12343.t10.CDS2 | 22648513 | 22648588 |
| chr_1 | g12343 | g12343.t10 | exon | g12343.t10.exon3 | 22648649 | 22649476 |
| chr_1 | g12343 | g12343.t10 | cds | g12343.t10.CDS3 | 22648649 | 22649476 |
| chr_1 | g12343 | g12343.t10 | exon | g12343.t10.exon4 | 22649541 | 22649664 |
| chr_1 | g12343 | g12343.t10 | cds | g12343.t10.CDS4 | 22649541 | 22649590 |
| chr_1 | g12343 | g12343.t10 | exon | g12343.t10.exon5 | 22649939 | 22650065 |
| chr_1 | g12343 | g12343.t10 | TTS | g12343.t10 | 22650062 | 22650062 |
Sequences
>g12343.t10 Gene=g12343 Length=1806
ATGTATCCAAATGTAAGTAATAGTATTTTATTTGGAATTTTTCATGAAAAAACAAAATTT
TAGTTTTTGCAATACTTTCATTTACATTTCATTGAAAATCAGTTTGAATTTAATACTGAG
AAACAATTGAAATGTAATATACTTCAATATTGGTTGATTTTCTTTATATATTTCTTTAAA
ATTCAGCAACAATCTGGTTACAATCAGTATAATCCACCATTTGGTGCAAATCCAAGCATG
CCAATGCCTCAATATCCTAATCAGATGCCTCAACCTTTTGGAGCTGGTTATTCTCAAATG
CCTGGAATGCCGATGCCACAACAAAATAATCCAAGCCCTTATGGCGGATTTCAAGGTCAA
ATGAATTATCAAAATCAAATGCCATCAATGAATCAGCAAATGCCTTATCAACCTCATCAA
CAAAACTTTGATTCATACAATCAGCAGCAGAATTCTTACCAACAACCTTATGCTCCACCT
AGCGTTTATCCAAATTTGCCGACTTCAGCTACCAGTCCTATTTATCAACATCAACAAAGT
AATGCTTCTTCTTATGGAACTCCAAATCAACATCAATACCAATCACCTCAATTTCAAATA
TCACAAAGTACACCAATGTATGGAAGTCAACAAACAGGACAAATTAAAAAGGGACGTCCA
ACAGTTACACCAGCATCGAATTTCAATGCTTCTAATGATTGTGCTATTTTACGAAAAGCT
ATGAAAGGATTTGGAACTGATGAAGATGCTATCATTTCTGTATTATGTCATCGAACTGTT
GATCAAAGAATGGAAATTGTTCGTACTTATAAGACAGCTTATGGCAAAGATCTGCTTAAT
GATATTCGCTCTGAAACATCAGGAAATTTTGAAAAGATCTTGATTGCACTACTTACACCA
ACAACTGAATTATATTGTCGTGAACTTTATGAAGCAATGGCTGGTGCGGGAACTGATGAG
GATGTACTCATTGAAGTTATGTGCACAATGTCAAATTATGAAATTCGTCAAATTTGTGCT
CAGTATGTACGTATGTATGGACAACCATTAGAACATCAATTACGAAGTGATACAAGCGGA
CATATGAAAAGACTTATGACATCTCTATCAGTTGGAGGACGTGATGAATCTATGCACACT
GATGTTAATCAAGCACGCGCTGATGCAGAAACATTGAGAGCTGCAGGAGTTGGACGATGG
GGAACTGATGAAAGTGAATTCAATCGCATTCTCTGTTTGCGAAATTATGAACAAATTAAA
CTCATATGCCAAGAATATGAAAAAATTACTGGAAGTTCTTTGGAAAAAGACATTAAAAAA
GAATTTAGTGGTGATATCGAGGATGCTCTTCTTGCCATTATTCGTGTTGCTAAAAATCGT
CCAGAATTCTTTGCTCGTCGTTTGCACAAATCGATGGCTGGTTTAGGCACTGATGATAAA
TCTTTAATTCGTTTGGTTGTCACACGATCTGAAATTGACATGATGGATATAAAAGACGAA
TTTCAACGTTATTATGGAAAGACACTCAAATCATTTATTAAAGGGGACACAAGTGGTCAT
TACAAGCATGCTCTTTATGCTCTTTGTGGCGAAAGTCGAAGTTAAATTATAAAAAATAAT
ATCAAAATCCAAAACCGTTTTTCGATTAACTAAAGTTTACTCAAATGGACTCAAATAAAC
AACTAATGTCAATAATGTAACTATTTTTAAATTTCTTAATTCTATTTTATAAACTAAATA
TGCTAACATTTATATTCATTGTTATCTCTCTCAAAAAAAATTTAATAAAAAGTTTTTATT
ATTGTT
>g12343.t10 Gene=g12343 Length=455
MPMPQYPNQMPQPFGAGYSQMPGMPMPQQNNPSPYGGFQGQMNYQNQMPSMNQQMPYQPH
QQNFDSYNQQQNSYQQPYAPPSVYPNLPTSATSPIYQHQQSNASSYGTPNQHQYQSPQFQ
ISQSTPMYGSQQTGQIKKGRPTVTPASNFNASNDCAILRKAMKGFGTDEDAIISVLCHRT
VDQRMEIVRTYKTAYGKDLLNDIRSETSGNFEKILIALLTPTTELYCRELYEAMAGAGTD
EDVLIEVMCTMSNYEIRQICAQYVRMYGQPLEHQLRSDTSGHMKRLMTSLSVGGRDESMH
TDVNQARADAETLRAAGVGRWGTDESEFNRILCLRNYEQIKLICQEYEKITGSSLEKDIK
KEFSGDIEDALLAIIRVAKNRPEFFARRLHKSMAGLGTDDKSLIRLVVTRSEIDMMDIKD
EFQRYYGKTLKSFIKGDTSGHYKHALYALCGESRS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g12343.t10 | Gene3D | G3DSA:1.10.220.10 | - | 148 | 220 | 9.8E-29 |
| 15 | g12343.t10 | Gene3D | G3DSA:1.10.220.10 | - | 221 | 292 | 1.9E-22 |
| 17 | g12343.t10 | Gene3D | G3DSA:1.10.220.10 | - | 293 | 380 | 1.9E-30 |
| 14 | g12343.t10 | Gene3D | G3DSA:1.10.220.10 | - | 382 | 453 | 4.8E-27 |
| 24 | g12343.t10 | MobiDBLite | mobidb-lite | consensus disorder prediction | 96 | 117 | - |
| 5 | g12343.t10 | PANTHER | PTHR10502 | ANNEXIN | 91 | 451 | 2.2E-135 |
| 6 | g12343.t10 | PANTHER | PTHR10502:SF226 | ANNEXIN | 91 | 451 | 2.2E-135 |
| 12 | g12343.t10 | PRINTS | PR00196 | Annexin family signature | 163 | 185 | 1.9E-50 |
| 10 | g12343.t10 | PRINTS | PR00196 | Annexin family signature | 203 | 219 | 1.9E-50 |
| 8 | g12343.t10 | PRINTS | PR00196 | Annexin family signature | 230 | 251 | 1.9E-50 |
| 9 | g12343.t10 | PRINTS | PR00196 | Annexin family signature | 313 | 339 | 1.9E-50 |
| 11 | g12343.t10 | PRINTS | PR00196 | Annexin family signature | 393 | 413 | 1.9E-50 |
| 7 | g12343.t10 | PRINTS | PR00196 | Annexin family signature | 437 | 450 | 1.9E-50 |
| 2 | g12343.t10 | Pfam | PF00191 | Annexin | 154 | 218 | 3.7E-25 |
| 4 | g12343.t10 | Pfam | PF00191 | Annexin | 228 | 290 | 1.5E-20 |
| 3 | g12343.t10 | Pfam | PF00191 | Annexin | 309 | 374 | 5.1E-23 |
| 1 | g12343.t10 | Pfam | PF00191 | Annexin | 384 | 449 | 2.8E-22 |
| 19 | g12343.t10 | ProSitePatterns | PS00223 | Annexin repeat signature. | 166 | 218 | - |
| 18 | g12343.t10 | ProSitePatterns | PS00223 | Annexin repeat signature. | 397 | 449 | - |
| 27 | g12343.t10 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 149 | 220 | 29.924 |
| 25 | g12343.t10 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 221 | 292 | 24.503 |
| 28 | g12343.t10 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 304 | 376 | 30.231 |
| 26 | g12343.t10 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 380 | 451 | 28.889 |
| 23 | g12343.t10 | SMART | SM00335 | annex3 | 166 | 218 | 1.2E-24 |
| 21 | g12343.t10 | SMART | SM00335 | annex3 | 238 | 290 | 7.4E-18 |
| 22 | g12343.t10 | SMART | SM00335 | annex3 | 322 | 374 | 3.8E-22 |
| 20 | g12343.t10 | SMART | SM00335 | annex3 | 397 | 449 | 3.9E-22 |
| 13 | g12343.t10 | SUPERFAMILY | SSF47874 | Annexin | 112 | 451 | 1.03E-121 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005544 | calcium-dependent phospholipid binding | MF |
| GO:0005509 | calcium ion binding | MF |
KEGG
Orthology
- This transcript has been annotated with K17093 (annexin A4)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed