General information for g12343.t7
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Annexin B11.
Parent gene
- The parent gene g12343 is located on chr_1: 22649445..22650065 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12343 | g12343.t7 | TSS | g12343.t7 | 22647505 | 22647505 |
| chr_1 | g12343 | g12343.t7 | isoform | g12343.t7 | 22647634 | 22650065 |
| chr_1 | g12343 | g12343.t7 | exon | g12343.t7.exon1 | 22647634 | 22647645 |
| chr_1 | g12343 | g12343.t7 | cds | g12343.t7.CDS1 | 22647634 | 22647645 |
| chr_1 | g12343 | g12343.t7 | exon | g12343.t7.exon2 | 22647820 | 22648288 |
| chr_1 | g12343 | g12343.t7 | cds | g12343.t7.CDS2 | 22647820 | 22648288 |
| chr_1 | g12343 | g12343.t7 | exon | g12343.t7.exon3 | 22648535 | 22648588 |
| chr_1 | g12343 | g12343.t7 | cds | g12343.t7.CDS3 | 22648535 | 22648588 |
| chr_1 | g12343 | g12343.t7 | exon | g12343.t7.exon4 | 22648649 | 22649476 |
| chr_1 | g12343 | g12343.t7 | cds | g12343.t7.CDS4 | 22648649 | 22649476 |
| chr_1 | g12343 | g12343.t7 | exon | g12343.t7.exon5 | 22649541 | 22650065 |
| chr_1 | g12343 | g12343.t7 | cds | g12343.t7.CDS5 | 22649541 | 22649590 |
| chr_1 | g12343 | g12343.t7 | TTS | g12343.t7 | 22650062 | 22650062 |
Sequences
>g12343.t7 Gene=g12343 Length=1888
ATGTATCCAAATCAACAATCTGGTTACAATCAGTATAATCCACCATTTGGTGCAAATCCA
AGCATGCCAATGCCTCAATATCCTAATCAGATGCCTCAACCTTTTGGAGCTGGTTATTCT
CAAATGCCTGGAATGCCGATGCCACAACAAAATAATCCAAGCCCTTATGGCGGATTTCAA
GGTCAAATGAATTATCAAAATCAAATGCCATCAATGAATCAGCAAATGCCTTATCAACCT
CATCAACAAAACTTTGATTCATACAATCAGCAGCAGAATTCTTACCAACAACCTTATGCT
CCACCTAGCGTTTATCCAAATTTGCCGACTTCAGCTACCAGTCCTATTTATCAACATCAA
CAAAGTAATGCTTCTTCTTATGGAACTCCAAATCAACATCAATACCAATCACCTCAATTT
CAAATATCACAAAGTACACCAATGTATGGAAGTCAACAAACAGGACAAATTAAAAAGGTT
ACATCGAATTTCAATGCTTCTAATGATTGTGCTATTTTACGAAAAGCTATGAAAGGATTT
GGAACTGATGAAGATGCTATCATTTCTGTATTATGTCATCGAACTGTTGATCAAAGAATG
GAAATTGTTCGTACTTATAAGACAGCTTATGGCAAAGATCTGCTTAATGATATTCGCTCT
GAAACATCAGGAAATTTTGAAAAGATCTTGATTGCACTACTTACACCAACAACTGAATTA
TATTGTCGTGAACTTTATGAAGCAATGGCTGGTGCGGGAACTGATGAGGATGTACTCATT
GAAGTTATGTGCACAATGTCAAATTATGAAATTCGTCAAATTTGTGCTCAGTATGTACGT
ATGTATGGACAACCATTAGAACATCAATTACGAAGTGATACAAGCGGACATATGAAAAGA
CTTATGACATCTCTATCAGTTGGAGGACGTGATGAATCTATGCACACTGATGTTAATCAA
GCACGCGCTGATGCAGAAACATTGAGAGCTGCAGGAGTTGGACGATGGGGAACTGATGAA
AGTGAATTCAATCGCATTCTCTGTTTGCGAAATTATGAACAAATTAAACTCATATGCCAA
GAATATGAAAAAATTACTGGAAGTTCTTTGGAAAAAGACATTAAAAAAGAATTTAGTGGT
GATATCGAGGATGCTCTTCTTGCCATTATTCGTGTTGCTAAAAATCGTCCAGAATTCTTT
GCTCGTCGTTTGCACAAATCGATGGCTGGTTTAGGCACTGATGATAAATCTTTAATTCGT
TTGGTTGTCACACGATCTGAAATTGACATGATGGATATAAAAGACGAATTTCAACGTTAT
TATGGAAAGACACTCAAATCATTTATTAAAGGGGACACAAGTGGTCATTACAAGCATGCT
CTTTATGCTCTTTGTGGCGAAAGTCGAAGTTAAATTATAAAAAATAATATCAAAATCCAA
AACCGTTTTTCGATTAACTAAAGTTTACTCAAATGGACTCAAATAAAGTTAGTTGAGTTT
TAATTGAAGAAAATTTTAATTAAATTTAGGTAAGTTCCAACTTAAATTTAAAACGGTTTT
GGATTCTGAAAATTATTAATATTAAAGTCCGAAACTGTTTAATATTTTAGTCGCGAATAA
CTAAAATTCAACTAAATCTAGTTGATTAAATTTAATGTTTTAATCCGCTTGTGATTCTCT
ACTTACTAAGTTGAATTTTAGTTATTCATAAAACGGTTTAAGACTTTGATTAATATCATA
TTTTTCTTACAAACCTTTTAGCAACTAATGTCAATAATGTAACTATTTTTAAATTTCTTA
ATTCTATTTTATAAACTAAATATGCTAACATTTATATTCATTGTTATCTCTCTCAAAAAA
AATTTAATAAAAAGTTTTTATTATTGTT
>g12343.t7 Gene=g12343 Length=470
MYPNQQSGYNQYNPPFGANPSMPMPQYPNQMPQPFGAGYSQMPGMPMPQQNNPSPYGGFQ
GQMNYQNQMPSMNQQMPYQPHQQNFDSYNQQQNSYQQPYAPPSVYPNLPTSATSPIYQHQ
QSNASSYGTPNQHQYQSPQFQISQSTPMYGSQQTGQIKKVTSNFNASNDCAILRKAMKGF
GTDEDAIISVLCHRTVDQRMEIVRTYKTAYGKDLLNDIRSETSGNFEKILIALLTPTTEL
YCRELYEAMAGAGTDEDVLIEVMCTMSNYEIRQICAQYVRMYGQPLEHQLRSDTSGHMKR
LMTSLSVGGRDESMHTDVNQARADAETLRAAGVGRWGTDESEFNRILCLRNYEQIKLICQ
EYEKITGSSLEKDIKKEFSGDIEDALLAIIRVAKNRPEFFARRLHKSMAGLGTDDKSLIR
LVVTRSEIDMMDIKDEFQRYYGKTLKSFIKGDTSGHYKHALYALCGESRS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g12343.t7 | Gene3D | G3DSA:1.10.220.10 | - | 163 | 235 | 1.0E-28 |
| 15 | g12343.t7 | Gene3D | G3DSA:1.10.220.10 | - | 236 | 307 | 2.0E-22 |
| 14 | g12343.t7 | Gene3D | G3DSA:1.10.220.10 | - | 308 | 395 | 2.0E-30 |
| 17 | g12343.t7 | Gene3D | G3DSA:1.10.220.10 | - | 397 | 468 | 5.0E-27 |
| 24 | g12343.t7 | MobiDBLite | mobidb-lite | consensus disorder prediction | 117 | 138 | - |
| 5 | g12343.t7 | PANTHER | PTHR10502 | ANNEXIN | 93 | 466 | 1.4E-133 |
| 6 | g12343.t7 | PANTHER | PTHR10502:SF226 | ANNEXIN | 93 | 466 | 1.4E-133 |
| 12 | g12343.t7 | PRINTS | PR00196 | Annexin family signature | 178 | 200 | 2.3E-50 |
| 11 | g12343.t7 | PRINTS | PR00196 | Annexin family signature | 218 | 234 | 2.3E-50 |
| 10 | g12343.t7 | PRINTS | PR00196 | Annexin family signature | 245 | 266 | 2.3E-50 |
| 8 | g12343.t7 | PRINTS | PR00196 | Annexin family signature | 328 | 354 | 2.3E-50 |
| 9 | g12343.t7 | PRINTS | PR00196 | Annexin family signature | 408 | 428 | 2.3E-50 |
| 7 | g12343.t7 | PRINTS | PR00196 | Annexin family signature | 452 | 465 | 2.3E-50 |
| 4 | g12343.t7 | Pfam | PF00191 | Annexin | 169 | 233 | 3.9E-25 |
| 1 | g12343.t7 | Pfam | PF00191 | Annexin | 243 | 305 | 1.6E-20 |
| 3 | g12343.t7 | Pfam | PF00191 | Annexin | 324 | 389 | 5.3E-23 |
| 2 | g12343.t7 | Pfam | PF00191 | Annexin | 399 | 464 | 2.9E-22 |
| 18 | g12343.t7 | ProSitePatterns | PS00223 | Annexin repeat signature. | 181 | 233 | - |
| 19 | g12343.t7 | ProSitePatterns | PS00223 | Annexin repeat signature. | 412 | 464 | - |
| 28 | g12343.t7 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 164 | 235 | 29.924 |
| 27 | g12343.t7 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 236 | 307 | 24.503 |
| 26 | g12343.t7 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 319 | 391 | 30.231 |
| 25 | g12343.t7 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 395 | 466 | 28.889 |
| 21 | g12343.t7 | SMART | SM00335 | annex3 | 181 | 233 | 1.2E-24 |
| 22 | g12343.t7 | SMART | SM00335 | annex3 | 253 | 305 | 7.4E-18 |
| 20 | g12343.t7 | SMART | SM00335 | annex3 | 337 | 389 | 3.8E-22 |
| 23 | g12343.t7 | SMART | SM00335 | annex3 | 412 | 464 | 3.9E-22 |
| 13 | g12343.t7 | SUPERFAMILY | SSF47874 | Annexin | 163 | 466 | 1.57E-118 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005544 | calcium-dependent phospholipid binding | MF |
| GO:0005509 | calcium ion binding | MF |
KEGG
Orthology
- This transcript has been annotated with K17093 (annexin A4)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed