General information for g12361.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Broad-complex core protein isoform 6.
Parent gene
- The parent gene g12361 is located on chr_1: 22909213..22913177 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12361 | g12361.t2 | isoform | g12361.t2 | 22898387 | 22909213 |
| chr_1 | g12361 | g12361.t2 | exon | g12361.t2.exon1 | 22898387 | 22898721 |
| chr_1 | g12361 | g12361.t2 | cds | g12361.t2.CDS1 | 22898387 | 22898721 |
| chr_1 | g12361 | g12361.t2 | exon | g12361.t2.exon2 | 22905376 | 22905426 |
| chr_1 | g12361 | g12361.t2 | cds | g12361.t2.CDS2 | 22905376 | 22905426 |
| chr_1 | g12361 | g12361.t2 | exon | g12361.t2.exon3 | 22905623 | 22905786 |
| chr_1 | g12361 | g12361.t2 | cds | g12361.t2.CDS3 | 22905623 | 22905786 |
| chr_1 | g12361 | g12361.t2 | exon | g12361.t2.exon4 | 22905846 | 22906140 |
| chr_1 | g12361 | g12361.t2 | cds | g12361.t2.CDS4 | 22905846 | 22906140 |
| chr_1 | g12361 | g12361.t2 | exon | g12361.t2.exon5 | 22906201 | 22906488 |
| chr_1 | g12361 | g12361.t2 | cds | g12361.t2.CDS5 | 22906201 | 22906488 |
| chr_1 | g12361 | g12361.t2 | exon | g12361.t2.exon6 | 22906578 | 22906722 |
| chr_1 | g12361 | g12361.t2 | cds | g12361.t2.CDS6 | 22906578 | 22906722 |
| chr_1 | g12361 | g12361.t2 | exon | g12361.t2.exon7 | 22907032 | 22907220 |
| chr_1 | g12361 | g12361.t2 | cds | g12361.t2.CDS7 | 22907032 | 22907220 |
| chr_1 | g12361 | g12361.t2 | exon | g12361.t2.exon8 | 22909028 | 22909213 |
| chr_1 | g12361 | g12361.t2 | cds | g12361.t2.CDS8 | 22909028 | 22909213 |
| chr_1 | g12361 | g12361.t2 | TSS | g12361.t2 | 22909336 | 22909336 |
| chr_1 | g12361 | g12361.t2 | TTS | g12361.t2 | NA | NA |
Sequences
>g12361.t2 Gene=g12361 Length=1653
ATGGTGGATACTCAACACTTTTGTCTGCGATGGAATAACTATCAGAGCAGCATTACATCG
GCGTTTGAAAATCTTCGCGATGATGAGGATTTCGTTGACGTCACACTGGCCTGTGATGGA
AGGAGCTTAAAAGCTCATCGCGTTGTGTTATCAGCATGTAGTCCTTACTTTCGTGAGCTC
TTAAAGAGCACACCATGCAAGCATCCCGTTATTGTACTTCAAGATGTTGCATTCACTGAT
TTGCACGCCCTTGTTGAATTCATCTATCATGGTGAAGTGAATGTTCATCAACGCTCATTG
AGCTCATTTTTAAAGACAGCAGAGGTCCTTCGTGTATCAGGATTAACACAGCAACAGGCT
GAAGAGACTCACAATTTAGCTCAAGTACAAAATATGGCACAAGCAGGTGGCAGAACACCT
ATGAATCATCATCAAAGTTTCACAGACAAGTTGGTCGAAGAAGCACTTCAATTTCCACAT
GGAGCATCACCACCATTGAACAATATGCATAATCCATCAGCACATTCAGGTGCAACAGTA
AATCAACTTTTGCGTCGTGCAGCAGCTGCAGCAGCAATGAGACGCGAACGCAACAGTTCA
TGCCAATCAGATGATTTGCAATTAAAACGTCATCGTCCAGATAGTGGACTTATGGGCCCC
AATATCAATAATAATAACAACAGCCTCGATATTATCAATCATATGCCACAAATTACGGCG
ACTGACTTCTCGACCAATATTAAGCACATGAACAATATTTCGCCACATATTAAAGACAGT
GATCGTATGGATGTAAAGACACCGAATGGCAACAATAATAACACTCTCGCCACTAACAAC
AACAATCCGAACAGCAGCAACAACAATCTTAAGGAAACGATCAATTTGACGACTAATGGA
AATGGTGGTGGAAGTTTGGGCTCAACAACTGATAAGGAAAGCTTGACACCATCACCATCT
GCACGCTCAACTGATGATGTAAAAACAGAACCTTTGGAAATGGTTAGCAATAGCATTGGA
CCTGACGATGAACACAGCAATGATTCAGTAGTTGATGCCGATCGACATTCAAGTAATGGA
AATGAATCGAAAGGACCACTTAGATTAAAATACAATTTTAGTGGACCTCATGAAGATGAA
ATGGATCCCGGCATGCACAATCATACTGCGCCACCTTTCTTGATGTCACCTGGTGATAAA
TTATTTCCACCACCGGGTTCATTCAATTTCTCTATGGCTGCTCTCGCTGATCCAACTGCT
CTAGCTAACTTCAACTCGATGCAATCTGCCGCTGCTGAATTGGCTGGATCGCCTCAAGCC
TCAACTGGTGGACTGTCATCAACACCAACTCCTCTTACGGAAGACTTTCGATGCGATCCA
TGCAACAAAAATTTATCATCACTGACGCGTTTAAAGCGACATATTCAAAATGTTCATATG
AGACCAACAAAAGAGCCAGTCTGTAACATTTGCAAGCGTGTCTATAGCTCATTGAATAGT
TTAAGAAATCATAAAAGCATTTATCATCGTAATATGAAGCAGCCAAAAGTTGAAGCAAAA
GACGATGGCGGAAATGTAGCAAATAATCCCGTCCCTGCTGCTCTTCGAACGCCAAACTAT
CCATTCTTTCCGATAAATCCGCGAACTGCCTAA
>g12361.t2 Gene=g12361 Length=550
MVDTQHFCLRWNNYQSSITSAFENLRDDEDFVDVTLACDGRSLKAHRVVLSACSPYFREL
LKSTPCKHPVIVLQDVAFTDLHALVEFIYHGEVNVHQRSLSSFLKTAEVLRVSGLTQQQA
EETHNLAQVQNMAQAGGRTPMNHHQSFTDKLVEEALQFPHGASPPLNNMHNPSAHSGATV
NQLLRRAAAAAAMRRERNSSCQSDDLQLKRHRPDSGLMGPNINNNNNSLDIINHMPQITA
TDFSTNIKHMNNISPHIKDSDRMDVKTPNGNNNNTLATNNNNPNSSNNNLKETINLTTNG
NGGGSLGSTTDKESLTPSPSARSTDDVKTEPLEMVSNSIGPDDEHSNDSVVDADRHSSNG
NESKGPLRLKYNFSGPHEDEMDPGMHNHTAPPFLMSPGDKLFPPPGSFNFSMAALADPTA
LANFNSMQSAAAELAGSPQASTGGLSSTPTPLTEDFRCDPCNKNLSSLTRLKRHIQNVHM
RPTKEPVCNICKRVYSSLNSLRNHKSIYHRNMKQPKVEAKDDGGNVANNPVPAALRTPNY
PFFPINPRTA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g12361.t2 | CDD | cd18315 | BTB_POZ_BAB-like | 31 | 114 | 8.42091E-38 |
| 8 | g12361.t2 | Gene3D | G3DSA:3.30.710.10 | Potassium Channel Kv1.1; Chain A | 5 | 119 | 9.9E-30 |
| 7 | g12361.t2 | Gene3D | G3DSA:3.30.160.60 | Classic Zinc Finger | 453 | 529 | 5.4E-9 |
| 15 | g12361.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 301 | 325 | - |
| 17 | g12361.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 301 | 368 | - |
| 16 | g12361.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 345 | 361 | - |
| 3 | g12361.t2 | PANTHER | PTHR23110 | BTB DOMAIN TRANSCRIPTION FACTOR | 1 | 514 | 4.0E-143 |
| 4 | g12361.t2 | PANTHER | PTHR23110:SF89 | BROAD-COMPLEX CORE PROTEIN ISOFORM 6 | 1 | 514 | 4.0E-143 |
| 2 | g12361.t2 | Pfam | PF00651 | BTB/POZ domain | 22 | 121 | 8.6E-25 |
| 1 | g12361.t2 | Pfam | PF13912 | C2H2-type zinc finger | 487 | 510 | 1.6E-4 |
| 10 | g12361.t2 | ProSitePatterns | PS00028 | Zinc finger C2H2 type domain signature. | 458 | 479 | - |
| 11 | g12361.t2 | ProSitePatterns | PS00028 | Zinc finger C2H2 type domain signature. | 488 | 509 | - |
| 20 | g12361.t2 | ProSiteProfiles | PS50097 | BTB domain profile. | 32 | 97 | 21.388 |
| 18 | g12361.t2 | ProSiteProfiles | PS50157 | Zinc finger C2H2 type domain profile. | 456 | 484 | 10.159 |
| 19 | g12361.t2 | ProSiteProfiles | PS50157 | Zinc finger C2H2 type domain profile. | 486 | 514 | 8.6 |
| 12 | g12361.t2 | SMART | SM00225 | BTB_4 | 32 | 127 | 3.2E-23 |
| 14 | g12361.t2 | SMART | SM00355 | c2h2final6 | 456 | 479 | 0.096 |
| 13 | g12361.t2 | SMART | SM00355 | c2h2final6 | 486 | 509 | 1.1 |
| 6 | g12361.t2 | SUPERFAMILY | SSF54695 | POZ domain | 7 | 117 | 7.85E-28 |
| 5 | g12361.t2 | SUPERFAMILY | SSF57667 | beta-beta-alpha zinc fingers | 456 | 505 | 2.31E-6 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K02174 (broad-complex core protein)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
