General information for g12517.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Anaphase-promoting complex subunit 1.
Parent gene
- The parent gene g12517 is located on chr_1: 24220243..24229622 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12517 | g12517.t1 | TTS | g12517.t1 | 24218418 | 24218418 |
| chr_1 | g12517 | g12517.t1 | isoform | g12517.t1 | 24218484 | 24224219 |
| chr_1 | g12517 | g12517.t1 | exon | g12517.t1.exon1 | 24218484 | 24218918 |
| chr_1 | g12517 | g12517.t1 | cds | g12517.t1.CDS1 | 24218484 | 24218918 |
| chr_1 | g12517 | g12517.t1 | exon | g12517.t1.exon2 | 24218970 | 24220243 |
| chr_1 | g12517 | g12517.t1 | cds | g12517.t1.CDS2 | 24218970 | 24220243 |
| chr_1 | g12517 | g12517.t1 | exon | g12517.t1.exon3 | 24220302 | 24221387 |
| chr_1 | g12517 | g12517.t1 | cds | g12517.t1.CDS3 | 24220302 | 24221387 |
| chr_1 | g12517 | g12517.t1 | exon | g12517.t1.exon4 | 24221457 | 24223449 |
| chr_1 | g12517 | g12517.t1 | cds | g12517.t1.CDS4 | 24221457 | 24223449 |
| chr_1 | g12517 | g12517.t1 | exon | g12517.t1.exon5 | 24223509 | 24224219 |
| chr_1 | g12517 | g12517.t1 | cds | g12517.t1.CDS5 | 24223509 | 24224219 |
| chr_1 | g12517 | g12517.t1 | TSS | g12517.t1 | 24224361 | 24224361 |
Sequences
>g12517.t1 Gene=g12517 Length=5499
ATGATTGCTGCCGCAGAACCAAAGGAGTATATTCCGAGTGGCAGAAAAATTGTAGAAGAG
CATTGTGGTCCATTAAATCGAAGAGCTGATACTATTTCTAGCGAATTTCTTCTCCTTGAT
CGTATGAAAAATGTAAATTTAAGTGCAGATGAACACTTTAATGAATCGTGGACTATACGG
CCAGTGTGCGATTATCGAAAAACAAAAGACTTGAATGATGAACTTTTATTTCTGGAACCG
CATATTGTAAATTCAGAAGAAGAGCTTTATTTCTCCGGACATACTGCTGTTTGGTCGAGT
AAAGTATCAGAAACCTGCTATACAACGGAAGATCCAATCAAATCTGCATTCTTTTGCACA
AGGAGTTTTCTTGATCCAGATTACAATATTCAAAATATTAAATCAAACAAAAATGAAGAC
AACGATAGTGATGCATTTAAAGGAATTGCAATAATTGACTCATCAAGTATGAAAGTTTAT
ACTAAAAGTGGTGAAATATTGGTTACAGCAGTTGAATCACCCATCAATAAAGTCTGGATA
ACGAAATACTGTGTAATTTTTGAGAAAGAAGCATCATCTTCTGCAATAGTCGATGGTCAT
CGACTTCCCATGCCTCGAATTTTCTCATTAACACATCCACTCGATGATATGTTTCCAGTC
TTGCTAAAATCTCAATCACTCATCAACTACATAACAGAAGAGGAATTTAAAATAATATTT
TCCACAGAAGAGAGCGATCTTATGTTAATGTTTAATTCTCGCAATGGAAAACATATGGTA
TGCAAATTAAGAAAAGCTACTGAAGAAGAAACACGTAGTGTCACAGCACTCTATGATACG
AGCAATATAGCCGGTGGGATAGGAACACATTCATCGATTGGTGGTTTTACAAGTCTTCAT
AATTCGAAAACACAAAAGAATAATTCAGGACGATATGGATCGATGGGAAATTTAAATGTT
ACTCATACCAATCAATCTAACAATTATCGTTCAAGCCTAGCTTCTTTAGCAGATTCATTC
AATCGCAACTCAATATCAATGATGGCTCGCAAAATTGGTGAATGTGAGCCTTCAAAAGCT
CTCGTCCCTGATCTTATTTTGGAACAAATTTGGACTGAAAATTCATCTAATTGGAATGAA
TATCAAGAAATGGCTTCAAAAGCTTTTCTACATAATGATTTTGTTGGACAGCAATTTCTT
TGTTTTCTACTACCAAAATGTTTTAAATTACAACTATTAATTATTGAGAGACTGAGTAGT
AACGATATGCCTGTATTTGGAGGTGTTTCAACTATTATTGCAAAGGATGCAGTTGCTTTA
CAAAAAATGAATATGATAATAGTTTTATTGCCTTGTGGAACTTTGATGATTTATTCTGGT
TTGGTTGCAGTTGGTAAAATTCATGTTGGAGGAATTTTAACAAATATTCCTTCTGCACTA
AGTACACCAGCTTTTCCTAAAAGATCAAGCATTTTGCCAAATATTGCTTCGCCATTGGTC
GATTTAAAATTGTCTGAAGAATTTCACAGTCTCTCGCCCGTGCATCCATTACAACCAACT
AATCCTTTGAGACTGAACAATTGCATGTCACTACGAGATCCTGTGGGAAATAGTTTGACA
ATCAGTTTCACAAATGGAAAGATGTATCGCTTTGAATTACCACAAATGTGTGAAAATCCA
ATCGTGAAAAAAGATTTAATTGCTCTAAGACAGATTCTACCAAAAGACGCAATGAAAATA
TTATCAAGATGGTATTCGATTAAAAATTCACCTGGTGCACGTGATTTGAGTTTAGGTCGA
GAATTTGAAATGTTTAAAAATTTATTATTTGAAATGATTGGTAGACCGCATGGTGTTTCA
CATTCATCAAGTTCAAATGCAATCACAGATCCTAAAAAACGTCGAAAAAGTGAAAATGGA
TCTGATTCAGATTGGGAATATTTAATATCTATTAAAAATGGAAACTGTAAATTCGAAGAT
GATGATCAAGAAATGATTCAAAATTACCATTCAGATGCTGTTCTTTTTTCAAATATTCCT
TTGATATTTTATTCATTACATTTACTTTATGAAGATCTTAAGTTGGATATTTCAATGAAC
AATGAATTGAATGCTCTGTCAGAGTTACTTTGTCAATTGGCTGTTGATTTCAAATTGGAA
AATTATAGATATCACTATGTAAAAGACAATCCACAATTAATTTATTTGAAATCTAAAATG
GAAATAGCTCAATATGACTCAAATAAGCTGCAAAATAAGGAATTGATTAATCAACCGATT
AGTATTTTCTATGAAATTTCACAATTGGCATCAAAGAAAGAATTCAAACAATATCCATAC
ATTCCTAATATCAATTTGCAATCGAAAAATGTTTTTGAAATTTTAGCAGTGATTTTTGAG
AGAGTCAAGTATCCGAGTGAAGCAACAATAATGATAAAGATTAGTGAAAATTATCAAGTG
ACAATGCAAAATAATATGAAGCCATTATCTGAACCAGGATCACTACATAAAATCGTGATT
GACACTATGATAAGAAAAGGAATAACAAGAGTTCATTTAGATCGTTTTCCAATTGCCATC
AATTATATTATATGTCAAATTTTAGAGACTGTTCGATTAAATCCGCCTATTGGATGCAAT
TCTGCTGCATACAAACTATTATTGAGACCTGAATTATACACGCATGCAGCTTATATGAAA
GATGATATAATTGCTCGATCTGAAAAGACATTGATTGAATACGACGGCATGGAAAATACG
GATACAAAACTTTTACGCTTACGCTTTCCTGATGATCTTCGCATAAATGATGTCAAGAAA
TTTCTCAATAGCTCAAAACCGGTAAGAATCGATGTAGTGCAGTCTCCAAATATGTCAGAT
CACGATTTTATTGAAGAACAAGAGAAGCAACTTTTTGCATTGTGTACTCGAACAATGGCA
CTTCCTATCGGTCGAGGAATGTTTACATTCAGAACTTATTATCCAGTTCTAACTGAAGTT
TTGCCAATTCCAAAACTTTGTCTAACTGGCAAAGAAAGTGTTCGGGGTACAACAGTTGAA
TTGCAACAAATTGAAGTGCCTGCAAATATGAGTGTATGGCCACAATTTCATAATGGTGTC
GCATCTGCTTTGAGAATTGCAACAGATCCACAACAAATCGATCCAGCTTACATTTTGTAC
AATAAACCTAAAGAAGCTGAAATGCCACCATCATATGCAGGATTTTTAATGGCACTTGGT
TTAACTTCGAGTTTGAAATCACTTTCTGACACTTATCTTTACGATTATCTTGTGAGATCA
GAAGAATTACTTAGCGTTGGTTTAATATTAGGGATGGCAGCAAGTTATAGAGAGACAATG
AATACAAAAATTACAAGAATGCTTTCAGTTCATATTGAATCACTTCTTCCACCAACTGCA
ATTGAATTAGATGTGCCTCATAATGTTCAAGTTGCATCATTATTAGGAATCGGATTACTC
TATCAGAAATCAAACAAGAGATTTATAGCAGAAGCATTATTACAAGAAATCAATCGACCG
CCTGGTCCAGAAATGGAAAATTATGTTGAACGAGAGTCATATGCTTTATCTGCTGGTCTT
GCTCTTGGCATGGTTTGTCTTGAGACTGGAAGTAAAGATGTTGGGCTTGATGATTTAAAT
TTACCTGATACACTTCATTATTATATGATTGGTGGTACTAAAAGAGGATTGACAGGAGTG
CAACGTGAAAAATATAAGCTTCCATCATTTCAAATACGTGAAGGTGATCAAGTTAATATC
GATGTGACTGCTCCAGGATCAACACTAGCACTTGGGTTAATGTTCTTTGCTAGCGGAAAT
GAAGCAGTTGCTGATTGGATGAAACCGCCCGAAACAATGTTTTTACTTGATTTTGTACGA
CCAGATCTTTTATTACTCCGAGTTATAGCAAGAGGTCTTATTATGTGGAATACTGTAGAA
CCAACTGCTGAATGGATCAATTCACAAATATCAAAATCACTTTCAAAAATCATTAAACAA
CGACCAGACCCAGATAATGATGATCTTGATCATGAAGCAATTTGTCAAGCATATTGTAAT
ATTGTGACTGGTGCTGCTATGATAATCGGTTTGAGATATGCTGGTACTGAAAATCTTATT
GCATTTAGAACATTGAAAAAGATTATTACATTTTTCTTATCTGCAAATGGTCAATATATT
GGTGAATATGCAGGAAAAGCAACAGTTGAGTCGTGTATAGTTCTCGTACTTATTGCTGCA
TCTTTAGTTTTTGCTGGAACTGGAAATTTACAAATTCTCAGAATGATTCGAATGACACGA
TCAAGAATTGGACCTCAACATAGTTCAGTAACTTATGGTTCACATATGGCAATTCACATG
GCATTAGGATTTCTTTTCTTAGGTGCTGGACGATATACAATTTCTCGTCGACCACAAGCA
ATTGCTGCTTTAATATGTGCTTTATTTCCGAAATTTCCAACTCATAGTAATGATAATCGA
TATCATTTGCAAGCACTTCGTCATTTATATGTACTAGCTGTTGAACCAAGATTATTTTTA
CCAAGAGATATTGATAATGGAAAATTGGTTGTATGCAAATTAAGTTATATTGAGTTTAAT
CAAAAGTCAATGGTTGAAACAATGGCACCTTGCATGCTACCTGAATTGGATTCATTAAAA
GCTGTCTATATAAATGATCCAAATTATTGGCCAGTTGTATTTGAAAGAGGAAGAAATTGG
GATCAATTAACTGAGATATTAAATGGAAATGGATGTATTGATATCGTACAGAAAGCTGGT
TGTTTGTCTCATCTTGATGATCCTAATCGTTTAAAAAGCATGCTTGCTTTAACATTAACT
ATGGAAGAATATTCAAATTGGAAAGTTGAAGCATCAAATTTAACATCATTTTATAATGAT
CAAATGATGAAAAGCTTGACAGAAATGATTATGACACAAGAAAAAGAAAAAAGTCCTTTA
CGTGAGATGATTTTATTACAAATTTATGATTGCCTAATGAGAGACAAAACTCATGCACTT
GGAATTTATATTTCAATTGATAATATAATTCAGTCTCTTAGTCATCAAAAGTCAATTAAA
TCAACTGATGTGTGGCAATTGAAAATTCTCAATATTCTTATGCATAATCGAATGCATAAG
GAATGTGATTCAAAATCATCGCTTGTATCTACAGAAATTCTTAATTCGTTACTTATGAAA
ATCAAATCAATCATTAATAACCGTATAGAACAGCAAAAATATCTTTTGAAAAAGTTTTTG
ACTCAAAAAAGCTTAGATTTTTTGCATCAAGAAGCTTGCTTACCAACAATTGAACAAGTC
TTGTTATTTACAAATTTCTTTGATCTCCCATTTGCTCTCTTTAGTTCACTTAATTCTGAA
AACATAAATTTGCTTCAATTTATTGTTGAATATAAAAAACGACATTCAACTACAGACACT
GAATTTTTGTCAAATTTATGGAAAATTGTGTCATCTTAA
>g12517.t1 Gene=g12517 Length=1832
MIAAAEPKEYIPSGRKIVEEHCGPLNRRADTISSEFLLLDRMKNVNLSADEHFNESWTIR
PVCDYRKTKDLNDELLFLEPHIVNSEEELYFSGHTAVWSSKVSETCYTTEDPIKSAFFCT
RSFLDPDYNIQNIKSNKNEDNDSDAFKGIAIIDSSSMKVYTKSGEILVTAVESPINKVWI
TKYCVIFEKEASSSAIVDGHRLPMPRIFSLTHPLDDMFPVLLKSQSLINYITEEEFKIIF
STEESDLMLMFNSRNGKHMVCKLRKATEEETRSVTALYDTSNIAGGIGTHSSIGGFTSLH
NSKTQKNNSGRYGSMGNLNVTHTNQSNNYRSSLASLADSFNRNSISMMARKIGECEPSKA
LVPDLILEQIWTENSSNWNEYQEMASKAFLHNDFVGQQFLCFLLPKCFKLQLLIIERLSS
NDMPVFGGVSTIIAKDAVALQKMNMIIVLLPCGTLMIYSGLVAVGKIHVGGILTNIPSAL
STPAFPKRSSILPNIASPLVDLKLSEEFHSLSPVHPLQPTNPLRLNNCMSLRDPVGNSLT
ISFTNGKMYRFELPQMCENPIVKKDLIALRQILPKDAMKILSRWYSIKNSPGARDLSLGR
EFEMFKNLLFEMIGRPHGVSHSSSSNAITDPKKRRKSENGSDSDWEYLISIKNGNCKFED
DDQEMIQNYHSDAVLFSNIPLIFYSLHLLYEDLKLDISMNNELNALSELLCQLAVDFKLE
NYRYHYVKDNPQLIYLKSKMEIAQYDSNKLQNKELINQPISIFYEISQLASKKEFKQYPY
IPNINLQSKNVFEILAVIFERVKYPSEATIMIKISENYQVTMQNNMKPLSEPGSLHKIVI
DTMIRKGITRVHLDRFPIAINYIICQILETVRLNPPIGCNSAAYKLLLRPELYTHAAYMK
DDIIARSEKTLIEYDGMENTDTKLLRLRFPDDLRINDVKKFLNSSKPVRIDVVQSPNMSD
HDFIEEQEKQLFALCTRTMALPIGRGMFTFRTYYPVLTEVLPIPKLCLTGKESVRGTTVE
LQQIEVPANMSVWPQFHNGVASALRIATDPQQIDPAYILYNKPKEAEMPPSYAGFLMALG
LTSSLKSLSDTYLYDYLVRSEELLSVGLILGMAASYRETMNTKITRMLSVHIESLLPPTA
IELDVPHNVQVASLLGIGLLYQKSNKRFIAEALLQEINRPPGPEMENYVERESYALSAGL
ALGMVCLETGSKDVGLDDLNLPDTLHYYMIGGTKRGLTGVQREKYKLPSFQIREGDQVNI
DVTAPGSTLALGLMFFASGNEAVADWMKPPETMFLLDFVRPDLLLLRVIARGLIMWNTVE
PTAEWINSQISKSLSKIIKQRPDPDNDDLDHEAICQAYCNIVTGAAMIIGLRYAGTENLI
AFRTLKKIITFFLSANGQYIGEYAGKATVESCIVLVLIAASLVFAGTGNLQILRMIRMTR
SRIGPQHSSVTYGSHMAIHMALGFLFLGAGRYTISRRPQAIAALICALFPKFPTHSNDNR
YHLQALRHLYVLAVEPRLFLPRDIDNGKLVVCKLSYIEFNQKSMVETMAPCMLPELDSLK
AVYINDPNYWPVVFERGRNWDQLTEILNGNGCIDIVQKAGCLSHLDDPNRLKSMLALTLT
MEEYSNWKVEASNLTSFYNDQMMKSLTEMIMTQEKEKSPLREMILLQIYDCLMRDKTHAL
GIYISIDNIIQSLSHQKSIKSTDVWQLKILNILMHNRMHKECDSKSSLVSTEILNSLLMK
IKSIINNRIEQQKYLLKKFLTQKSLDFLHQEACLPTIEQVLLFTNFFDLPFALFSSLNSE
NINLLQFIVEYKKRHSTTDTEFLSNLWKIVSS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g12517.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 621 | 641 | - |
| 2 | g12517.t1 | PANTHER | PTHR12827 | MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER | 50 | 1778 | 0.0 |
| 3 | g12517.t1 | PANTHER | PTHR12827:SF3 | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1 | 50 | 1778 | 0.0 |
| 1 | g12517.t1 | Pfam | PF18122 | Anaphase-promoting complex sub unit 1 C-terminal domain | 1634 | 1771 | 9.6E-13 |
| 9 | g12517.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 1412 | - |
| 11 | g12517.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1413 | 1433 | - |
| 7 | g12517.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1434 | 1453 | - |
| 10 | g12517.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1454 | 1474 | - |
| 8 | g12517.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1475 | 1832 | - |
| 5 | g12517.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1411 | 1433 | - |
| 4 | g12517.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1453 | 1475 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005680 | anaphase-promoting complex | CC |
KEGG
Orthology
- This transcript has been annotated with K03348 (anaphase-promoting complex subunit 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
