General information for g12645.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Serine protease inhibitor 77Ba.
Parent gene
- The parent gene g12645 is located on chr_1: 24991381..24992301 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12645 | g12645.t1 | isoform | g12645.t1 | 24991381 | 24992301 |
| chr_1 | g12645 | g12645.t1 | exon | g12645.t1.exon1 | 24991381 | 24991694 |
| chr_1 | g12645 | g12645.t1 | cds | g12645.t1.CDS1 | 24991381 | 24991694 |
| chr_1 | g12645 | g12645.t1 | exon | g12645.t1.exon2 | 24991763 | 24991982 |
| chr_1 | g12645 | g12645.t1 | cds | g12645.t1.CDS2 | 24991763 | 24991982 |
| chr_1 | g12645 | g12645.t1 | exon | g12645.t1.exon3 | 24992050 | 24992301 |
| chr_1 | g12645 | g12645.t1 | cds | g12645.t1.CDS3 | 24992050 | 24992301 |
| chr_1 | g12645 | g12645.t1 | TSS | g12645.t1 | NA | NA |
| chr_1 | g12645 | g12645.t1 | TTS | g12645.t1 | NA | NA |
Sequences
>g12645.t1 Gene=g12645 Length=786
ATGAGCTCTGCTGATCGCAAAACAACAAAATTACCTCTTATTTTGCCTACTTCTGTAGAT
ACTAATATTCGAAAATTATTATGGGATCAAGAATTGTCAGAAAATACTGAACTATTTGGA
TTGCACTTATTTTTGTATTTGACTCAATTTGAGTCTGAAAATTTCATGATTAATCCATAT
TTAATTCATTCACTTTTAGCAGTCCTTGCTGAAGGTGCAGTTGGTAATACATATAAAGAA
ATAAACAATGCTCTTGGTTTAATAAATAGACAACGAACAAGAGATTTCCATCAATATACT
AACTTAGCTTTAAGTAAAAGTGCGTCAGATGTGAACTTTCGTAAATTTGCTGCTATGATA
GGTGATCAAAATCGACCGATCACACGCGAATATGAAGACAATTTAGAAAAAATTTATGAT
GTAGAATACATTCCTGTAAATTTCAAAAATGTAGACAGAACTTTACGTGAAGTAAATGGC
AGAGTTTCACAAAGTACAAGTTGGTTAATAACTGACGTCATCTCACGTGAAGATACTCAG
TTAATACTGTTAGCATGTACTTATTTCAAAGGAAGCTGGAAAATTGCCTTCAATTCGACA
TTAACAAAGTATGAACCATTTTATGATATTAATGAGGAGGAAATAATTGGAAGAGTTAAT
ATGATGTCTCAAAGTGGTTCATTTGCTTATGTTTTTAATCAAAATCTTGGCTGTTATCTT
CTTGAATTACCATTTGGAATCGACCGTGAATATGCAAAAAGAATATTAATTGCCAGAAAG
CGCTGA
>g12645.t1 Gene=g12645 Length=261
MSSADRKTTKLPLILPTSVDTNIRKLLWDQELSENTELFGLHLFLYLTQFESENFMINPY
LIHSLLAVLAEGAVGNTYKEINNALGLINRQRTRDFHQYTNLALSKSASDVNFRKFAAMI
GDQNRPITREYEDNLEKIYDVEYIPVNFKNVDRTLREVNGRVSQSTSWLITDVISREDTQ
LILLACTYFKGSWKIAFNSTLTKYEPFYDINEEEIIGRVNMMSQSGSFAYVFNQNLGCYL
LELPFGIDREYAKRILIARKR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g12645.t1 | Gene3D | G3DSA:3.30.497.10 | Antithrombin | 22 | 190 | 0.0000 |
| 6 | g12645.t1 | Gene3D | G3DSA:2.30.39.10 | - | 191 | 260 | 0.0000 |
| 2 | g12645.t1 | PANTHER | PTHR11461:SF162 | SERINE PROTEASE INHIBITOR 77BA | 32 | 253 | 0.0000 |
| 3 | g12645.t1 | PANTHER | PTHR11461 | SERINE PROTEASE INHIBITOR, SERPIN | 32 | 253 | 0.0000 |
| 1 | g12645.t1 | Pfam | PF00079 | Serpin (serine protease inhibitor) | 38 | 248 | 0.0000 |
| 5 | g12645.t1 | SMART | SM00093 | serpin2 | 41 | 261 | 0.0067 |
| 4 | g12645.t1 | SUPERFAMILY | SSF56574 | Serpins | 29 | 255 | 0.0000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005615 | extracellular space | CC |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed