General information for g12646.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Serine protease inhibitor 77Ba.
Parent gene
- The parent gene g12646 is located on chr_1: 24992315..24992975 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12646 | g12646.t1 | isoform | g12646.t1 | 24992315 | 24992975 |
| chr_1 | g12646 | g12646.t1 | exon | g12646.t1.exon1 | 24992315 | 24992506 |
| chr_1 | g12646 | g12646.t1 | cds | g12646.t1.CDS1 | 24992315 | 24992506 |
| chr_1 | g12646 | g12646.t1 | exon | g12646.t1.exon2 | 24992563 | 24992721 |
| chr_1 | g12646 | g12646.t1 | cds | g12646.t1.CDS2 | 24992563 | 24992721 |
| chr_1 | g12646 | g12646.t1 | exon | g12646.t1.exon3 | 24992880 | 24992975 |
| chr_1 | g12646 | g12646.t1 | cds | g12646.t1.CDS3 | 24992880 | 24992975 |
| chr_1 | g12646 | g12646.t1 | TSS | g12646.t1 | NA | NA |
| chr_1 | g12646 | g12646.t1 | TTS | g12646.t1 | NA | NA |
Sequences
>g12646.t1 Gene=g12646 Length=447
ATGATTGTTGTTTTACCAAAACGTGGTCTTTCATTGATTGATGTCATTAATAACATTAGC
GTTTATGGAATAAAGACCTTGCTAATAGAATTGAAAAAAAGTAAAGAAGAAAATAAAAAC
TTAGAAGTTGAAGTTCATCTTCCACGTTTTGAAATAAACACATCACTCAATTTAAAGGAG
ACTTTAAAAGATTTGGAAATAAATGAGATTTTTGAGAATACAGCAAATTTGTCAGGAATC
AATTATAACTACTATGTTTCGTCGATTCTTCACAAGACAAAAATTAATGTAGATGAAAAA
GGATCTGAAGCACCAACAGTGACAAATTTAATTTCTGCTAACAAAGTCAAGTTCTATGCT
AACAGACCTTTTATTTACTTTATTCTTGACAAAGCCACGAGACTCATTCTTTTTGCTGGC
GTGTTTAAAAATCCTGCAGTTTTTTAA
>g12646.t1 Gene=g12646 Length=148
MIVVLPKRGLSLIDVINNISVYGIKTLLIELKKSKEENKNLEVEVHLPRFEINTSLNLKE
TLKDLEINEIFENTANLSGINYNYYVSSILHKTKINVDEKGSEAPTVTNLISANKVKFYA
NRPFIYFILDKATRLILFAGVFKNPAVF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g12646.t1 | Coils | Coil | Coil | 24 | 44 | - |
| 6 | g12646.t1 | Gene3D | G3DSA:2.30.39.10 | - | 1 | 145 | 1.2E-37 |
| 7 | g12646.t1 | Gene3D | G3DSA:3.30.497.10 | Antithrombin | 54 | 101 | 1.2E-37 |
| 2 | g12646.t1 | PANTHER | PTHR11461:SF162 | SERINE PROTEASE INHIBITOR 77BA | 1 | 146 | 5.1E-30 |
| 3 | g12646.t1 | PANTHER | PTHR11461 | SERINE PROTEASE INHIBITOR, SERPIN | 1 | 146 | 5.1E-30 |
| 1 | g12646.t1 | Pfam | PF00079 | Serpin (serine protease inhibitor) | 1 | 145 | 9.3E-35 |
| 5 | g12646.t1 | ProSitePatterns | PS00284 | Serpins signature. | 118 | 128 | - |
| 4 | g12646.t1 | SUPERFAMILY | SSF56574 | Serpins | 1 | 145 | 9.16E-36 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005615 | extracellular space | CC |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed