General information for g12721.t1
Yuki Yoshida
6/2/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Alcohol dehydrogenase class-3 chain L.
Parent gene
- The parent gene g12721 is located on chr_1: 25447712..25449299 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12721 | g12721.t1 | TTS | g12721.t1 | 25447573 | 25447573 |
| chr_1 | g12721 | g12721.t1 | isoform | g12721.t1 | 25447712 | 25449299 |
| chr_1 | g12721 | g12721.t1 | exon | g12721.t1.exon1 | 25447712 | 25448301 |
| chr_1 | g12721 | g12721.t1 | cds | g12721.t1.CDS1 | 25447712 | 25448301 |
| chr_1 | g12721 | g12721.t1 | exon | g12721.t1.exon2 | 25448624 | 25448870 |
| chr_1 | g12721 | g12721.t1 | cds | g12721.t1.CDS2 | 25448624 | 25448870 |
| chr_1 | g12721 | g12721.t1 | exon | g12721.t1.exon3 | 25448952 | 25449107 |
| chr_1 | g12721 | g12721.t1 | cds | g12721.t1.CDS3 | 25448952 | 25449107 |
| chr_1 | g12721 | g12721.t1 | exon | g12721.t1.exon4 | 25449165 | 25449299 |
| chr_1 | g12721 | g12721.t1 | cds | g12721.t1.CDS4 | 25449165 | 25449299 |
| chr_1 | g12721 | g12721.t1 | TSS | g12721.t1 | 25449342 | 25449342 |
Sequences
>g12721.t1 Gene=g12721 Length=1128
ATGACTGAAGGAAAAACTATAACGTGTCGAGCTGCAGTTGTTTGGAAGGCAAATGAGCCA
TTTGTCATTGAACAAATTGAAGTTGATCCACCAAAAGCTGGTGAAGTGCGAGTTAAAATT
GTCTCAACTGGAATTTGCTTCTCTGATGTAAGTGCATCAACAGGAAAAATTTTGGGAGTT
CAATTTCCAATAATTCTCGGTCATGAAGCCTCTGCAATTGTTGAATCAATTGGAGAAGGC
GTAGAAAGTGTGGGTGTAGGAGATCATGTTTTGCCTTTATTTTTACCGCAATGTAACAGA
TGTCGCGTTTGTAAAGATAAAAATGCTAATAGCTGTTTAGAGTTTATGGGATCACAAGTC
AAAGGCGTAATGTCAGATGGTACATCTCGTTTTCGGTGTCGAGGAGAAACTTTGTATACT
TTTGTTGGATGTTCGACATTCACAGAATATTCAGTGATAAGTGAAATTAATTTGGCAAAA
ATCAACCCTGAAGCTCCAATGAAGGAAGCTGCTCTTATAAGTTGTGGTATTTCAACTGGT
TATGGAGCAGCAATAAATTCTGCGGGTGTTAAAGAAAATAGCACTTGTGCTGTATGGGGA
TTGGGCACACTAGGCTTATCAACTATCATGGGATGTAAAAAAGCGGGTGCAAAGACTATT
ATCGGAATTGATATTATTCCAGAAAAATTCAAACTAGCAGCTGAAATGGGTTGCACAGAT
TTTGTAAATCCATCAGAATTGAGTGTACCTATTGAGCAATATTTAATGGAAAAATATGGT
GGTGCTATTGAGTATACTTTTGAGTGTATTGGAAGAATTCAAACGATGAAGCAAGCTTTT
GATTGCTGTGCTATTGGAAATGGAGTTTGTGTTTTAATTGGTGTAGCAGGCTTAACTGAT
AACTTGAACATTTCTCCTGGACAATTTCTAGCTGGAAAAACACTCAAAGGGACGCTTTAT
GGAGGCTATAAAAGTCGTGATGCAGTTCCCAAACTTGTTGATGAACTCATGAATGGAAAA
CTGAAAGTTGACAAATTCATAACACATACTATGAAATTGGATGATATTAATGAGGGCTTT
GATTTATTAAAAGCCGGAAAAAGTATTCGCACAATTCTTAATTTATAA
>g12721.t1 Gene=g12721 Length=375
MTEGKTITCRAAVVWKANEPFVIEQIEVDPPKAGEVRVKIVSTGICFSDVSASTGKILGV
QFPIILGHEASAIVESIGEGVESVGVGDHVLPLFLPQCNRCRVCKDKNANSCLEFMGSQV
KGVMSDGTSRFRCRGETLYTFVGCSTFTEYSVISEINLAKINPEAPMKEAALISCGISTG
YGAAINSAGVKENSTCAVWGLGTLGLSTIMGCKKAGAKTIIGIDIIPEKFKLAAEMGCTD
FVNPSELSVPIEQYLMEKYGGAIEYTFECIGRIQTMKQAFDCCAIGNGVCVLIGVAGLTD
NLNISPGQFLAGKTLKGTLYGGYKSRDAVPKLVDELMNGKLKVDKFITHTMKLDDINEGF
DLLKAGKSIRTILNL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g12721.t1 | Gene3D | G3DSA:3.90.180.10 | - | 12 | 370 | 0 |
| 7 | g12721.t1 | Gene3D | G3DSA:3.40.50.720 | - | 180 | 318 | 0 |
| 3 | g12721.t1 | PANTHER | PTHR43880 | ALCOHOL DEHYDROGENASE | 4 | 373 | 0 |
| 2 | g12721.t1 | Pfam | PF08240 | Alcohol dehydrogenase GroES-like domain | 34 | 126 | 0 |
| 1 | g12721.t1 | Pfam | PF00107 | Zinc-binding dehydrogenase | 204 | 334 | 0 |
| 6 | g12721.t1 | SUPERFAMILY | SSF50129 | GroES-like | 2 | 183 | 0 |
| 4 | g12721.t1 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 166 | 340 | 0 |
| 5 | g12721.t1 | SUPERFAMILY | SSF50129 | GroES-like | 325 | 373 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
## [1] "No matching GO terms"KEGG
Orthology
- This transcript has been annotated with K13952 (alcohol dehydrogenase 6)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
