General information for g12721.t7
Yuki Yoshida
6/2/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Alcohol dehydrogenase class-3 chain L.
Parent gene
- The parent gene g12721 is located on chr_1: 25447712..25449299 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12721 | g12721.t7 | TTS | g12721.t7 | 25447573 | 25447573 |
| chr_1 | g12721 | g12721.t7 | isoform | g12721.t7 | 25447712 | 25449299 |
| chr_1 | g12721 | g12721.t7 | exon | g12721.t7.exon1 | 25447712 | 25448289 |
| chr_1 | g12721 | g12721.t7 | cds | g12721.t7.CDS1 | 25447712 | 25448289 |
| chr_1 | g12721 | g12721.t7 | exon | g12721.t7.exon2 | 25448639 | 25449299 |
| chr_1 | g12721 | g12721.t7 | cds | g12721.t7.CDS2 | 25448639 | 25448816 |
| chr_1 | g12721 | g12721.t7 | TSS | g12721.t7 | 25449342 | 25449342 |
Sequences
>g12721.t7 Gene=g12721 Length=1239
ATGACTGAAGGAAAAACTATAACGTGTCGAGCTGCAGTTGTTTGGAAGGCAAATGAGCCA
TTTGTCATTGAACAAATTGAAGTTGATCCACCAAAAGCTGGTGAAGTGCGAGTTAAAATT
GTCTCAACTGGAATTGTAAGAGTGAAATTAATTTTTAACAATTTTGAAAATTGATTTTAT
TTTATTTATCAGTGCTTCTCTGATGTAAGTGCATCAACAGGAAAAATTTTGGGAGTTCAA
TTTCCAATAATTCTCGGTCATGAAGCCTCTGCAATTGTTGAATCAATTGGAGAAGGCGTA
GAAAGTGTGGGTGTAGGAGATCATGTTTTGCCTTTATTTTTACCGCAAGTATGTGTGCTT
TAAAAAGTTTTTACTTTTAGTCATTATTTTAATATAAATCAATCTACTTTATTTTTATAT
TATAAACAGTGTAACAGATGTCGCGTTTGTAAAGATAAAAATGCTAATAGCTGTTTAGAG
TTTATGGGATCACAAGTCAAAGGCGTAATGTCAGATGGTACATCTCGTTTTCGGTGTCGA
GGAGAAACTTTGTATACTTTTGTTGGATGTTCGACATTCACAGAATATTCAGTGATAAGT
GAAATTAATTTGGCAAAAATCAACCCTGAAGCTCCAATGAAGGAAGCTGCTCTTATAAGT
TCAATAAATTCTGCGGGTGTTAAAGAAAATAGCACTTGTGCTGTATGGGGATTGGGCACA
CTAGGCTTATCAACTATCATGGGATGTAAAAAAGCGGGTGCAAAGACTATTATCGGAATT
GATATTATTCCAGAAAAATTCAAACTAGCAGCTGAAATGGGTTGCACAGATTTTGTAAAT
CCATCAGAATTGAGTGTACCTATTGAGCAATATTTAATGGAAAAATATGGTGGTGCTATT
GAGTATACTTTTGAGTGTATTGGAAGAATTCAAACGATGAAGCAAGCTTTTGATTGCTGT
GCTATTGGAAATGGAGTTTGTGTTTTAATTGGTGTAGCAGGCTTAACTGATAACTTGAAC
ATTTCTCCTGGACAATTTCTAGCTGGAAAAACACTCAAAGGGACGCTTTATGGAGGCTAT
AAAAGTCGTGATGCAGTTCCCAAACTTGTTGATGAACTCATGAATGGAAAACTGAAAGTT
GACAAATTCATAACACATACTATGAAATTGGATGATATTAATGAGGGCTTTGATTTATTA
AAAGCCGGAAAAAGTATTCGCACAATTCTTAATTTATAA
>g12721.t7 Gene=g12721 Length=251
MGSQVKGVMSDGTSRFRCRGETLYTFVGCSTFTEYSVISEINLAKINPEAPMKEAALISS
INSAGVKENSTCAVWGLGTLGLSTIMGCKKAGAKTIIGIDIIPEKFKLAAEMGCTDFVNP
SELSVPIEQYLMEKYGGAIEYTFECIGRIQTMKQAFDCCAIGNGVCVLIGVAGLTDNLNI
SPGQFLAGKTLKGTLYGGYKSRDAVPKLVDELMNGKLKVDKFITHTMKLDDINEGFDLLK
AGKSIRTILNL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g12721.t7 | Gene3D | G3DSA:3.40.50.720 | - | 58 | 194 | 0.0e+00 |
| 7 | g12721.t7 | Gene3D | G3DSA:3.90.180.10 | - | 196 | 251 | 1.5e-05 |
| 2 | g12721.t7 | PANTHER | PTHR43880 | ALCOHOL DEHYDROGENASE | 4 | 249 | 0.0e+00 |
| 1 | g12721.t7 | Pfam | PF00107 | Zinc-binding dehydrogenase | 80 | 210 | 0.0e+00 |
| 4 | g12721.t7 | SUPERFAMILY | SSF50129 | GroES-like | 4 | 58 | 0.0e+00 |
| 3 | g12721.t7 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 61 | 216 | 0.0e+00 |
| 5 | g12721.t7 | SUPERFAMILY | SSF50129 | GroES-like | 201 | 249 | 0.0e+00 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
## [1] "No matching GO terms"KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed