Gene loci information

Transcript annotation

  • This transcript has been annotated as Aldo-keto reductase family 1 member B1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g12728 g12728.t14 TTS g12728.t14 25507381 25507381
chr_1 g12728 g12728.t14 isoform g12728.t14 25507464 25508407
chr_1 g12728 g12728.t14 exon g12728.t14.exon1 25507464 25507765
chr_1 g12728 g12728.t14 cds g12728.t14.CDS1 25507464 25507765
chr_1 g12728 g12728.t14 exon g12728.t14.exon2 25507838 25508407
chr_1 g12728 g12728.t14 cds g12728.t14.CDS2 25507838 25508153
chr_1 g12728 g12728.t14 TSS g12728.t14 25508972 25508972

Sequences

>g12728.t14 Gene=g12728 Length=872
CTGGTGTTGTTGCTCAAGCTGTAAAAGACGCAATTGATGCTGGCTATCGTCATTTTGACG
GTGCTCATGTATATGAAAATGAGCATGAAGTTGGTGAAGGAATTAATGCTAAAATCGCTG
AAGGTGTTATCAAACGTGAAGACGTTTTTGTAACATCAAAATTATGGTGCACTTTCCATG
ACCCAAAGGATGTTCGTGGTGCACTCGAGCATACATTGAAACAATTAAATTTAGATTATC
TTGACTTGTACCTCATGCATTGGCCTATTTGTTATCAAAAATCAACTGAATTGTTCCCAA
AGAATGAAGCTGGTGAAATTTTGCACGCTAATTTTGATATTCTTGACACTTATCGTGCAA
TGGAGGAACTTGTTGATGCTGGATTGACTAAAAGTATTGGAATTTCAAACTTCAATATCA
AACAAGTTGAGTACATTACTAAAAATGCTCGCATCCAACCAGTCACCAATCAAGTTGAAT
GCAATCCATATTTACTTAATAAAGAATTAAGTGATTTCTGCAAAAGTAAAAACATTGTCA
TCACCGCTTATTCACCTCTTGGTTCACCAGGTCGTCCATGGGCAACACCAGATGACCGAG
TATTATTAAAAGAACCAAAACTTTTAGAGATCGCTCAGAAGCACAATAAAACACCAGCAC
AAATTTTAATCCGTTACCAAATTCAACGCGGTCACGTTGTCATACCGAAATCAGTTACGA
AGGATCGCATAATCAGTAATTTTGATGTTTTCAACTTCACATTGAGCGATTCTGAAATAA
AAGATTTGGAAAACTTCAACTATACTGAGCGCATTTGTAGCATGTCTCAAGATAAACATC
ATCCAGCTTATCCTTTCAATGACGACGCCTAA

>g12728.t14 Gene=g12728 Length=205
MHWPICYQKSTELFPKNEAGEILHANFDILDTYRAMEELVDAGLTKSIGISNFNIKQVEY
ITKNARIQPVTNQVECNPYLLNKELSDFCKSKNIVITAYSPLGSPGRPWATPDDRVLLKE
PKLLEIAQKHNKTPAQILIRYQIQRGHVVIPKSVTKDRIISNFDVFNFTLSDSEIKDLEN
FNYTERICSMSQDKHHPAYPFNDDA

Protein features from InterProScan

Transcript Database ID Name Start End E.value
10 g12728.t14 Gene3D G3DSA:3.20.20.100 - 1 205 1.3E-79
2 g12728.t14 PANTHER PTHR11732:SF294 ALDO-KETO REDUCTASE FAMILY 1 MEMBER B1 1 203 1.5E-68
3 g12728.t14 PANTHER PTHR11732 ALDO/KETO REDUCTASE 1 203 1.5E-68
4 g12728.t14 PRINTS PR00069 Aldo-keto reductase signature 36 53 6.7E-33
6 g12728.t14 PRINTS PR00069 Aldo-keto reductase signature 70 99 6.7E-33
5 g12728.t14 PRINTS PR00069 Aldo-keto reductase signature 117 141 6.7E-33
1 g12728.t14 Pfam PF00248 Aldo/keto reductase family 2 180 1.1E-30
8 g12728.t14 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 36 53 -
9 g12728.t14 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 150 165 -
7 g12728.t14 SUPERFAMILY SSF51430 NAD(P)-linked oxidoreductase 1 200 1.96E-56

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0047834 D-threo-aldose 1-dehydrogenase activity MF
GO:0055114 NA NA
GO:0016491 oxidoreductase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed