General information for g12734.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Aldo-keto reductase family 1 member B15.
Parent gene
- The parent gene g12734 is located on chr_1: 25518444..25519323 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12734 | g12734.t2 | isoform | g12734.t2 | 25518444 | 25519323 |
| chr_1 | g12734 | g12734.t2 | exon | g12734.t2.exon1 | 25518444 | 25519017 |
| chr_1 | g12734 | g12734.t2 | cds | g12734.t2.CDS1 | 25518445 | 25518825 |
| chr_1 | g12734 | g12734.t2 | exon | g12734.t2.exon2 | 25519263 | 25519323 |
| chr_1 | g12734 | g12734.t2 | TSS | g12734.t2 | 25519375 | 25519375 |
| chr_1 | g12734 | g12734.t2 | TTS | g12734.t2 | NA | NA |
Sequences
>g12734.t2 Gene=g12734 Length=635
ATGTCACCAGTTCATACTTTAGTTTTGAATAATGGAAAGAAAATTCCCATTGTTGGTTTA
GTCACCACCTGGTGTTGTTGCTCAAGCTGTAAAAGATGCAATTGATGCTGGCTATCGTCA
TATTGATTGTGCTCATTGCTATCAAAATGAACATGAAGTTGGTGAAGGAATCAATGCCAA
AATCGCTGAAGGTGTTATCAAACGTGAAGACATTTTTGTAACATCAAAATTATGGAACAC
TCATCATGAACCGATGGATGTTAAGCCAGCACTTCAGCATACATTGAAGCAACTAAATTT
ATCCTATGTTGACTTATATTTAATTCATTGGCCATTCGCCTATCAAAAGTCGGATGAAAT
TTTTCCAAGAGATTCAAATGGAAAAATTTTGCATTCAAGAGTTGATTTTGTTGACACTTA
TCGTGCAATGGAATATCTTGTTGATGATGGTTTAGCAAAAAGTATTGGAGTGTCAAATTT
TAATATTCAACAACTTGAGTATATTCTCAAGAATGCTCGTATTCAACCAGTCACTAATCA
AATTGAATGCCATCCATATTTGTTAAATAAGAAATTAAGTGAATATTGCAAGAGCAAAAA
TATTCTTATAACTGCTTATTCACCACTTGGTTCAC
>g12734.t2 Gene=g12734 Length=127
MDVKPALQHTLKQLNLSYVDLYLIHWPFAYQKSDEIFPRDSNGKILHSRVDFVDTYRAME
YLVDDGLAKSIGVSNFNIQQLEYILKNARIQPVTNQIECHPYLLNKKLSEYCKSKNILIT
AYSPLGS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g12734.t2 | Gene3D | G3DSA:3.20.20.100 | - | 1 | 127 | 5.5E-54 |
| 2 | g12734.t2 | PANTHER | PTHR11732:SF482 | ZGC:56622 | 2 | 127 | 3.6E-48 |
| 3 | g12734.t2 | PANTHER | PTHR11732 | ALDO/KETO REDUCTASE | 2 | 127 | 3.6E-48 |
| 5 | g12734.t2 | PRINTS | PR00069 | Aldo-keto reductase signature | 9 | 27 | 6.4E-31 |
| 4 | g12734.t2 | PRINTS | PR00069 | Aldo-keto reductase signature | 59 | 76 | 6.4E-31 |
| 6 | g12734.t2 | PRINTS | PR00069 | Aldo-keto reductase signature | 93 | 122 | 6.4E-31 |
| 1 | g12734.t2 | Pfam | PF00248 | Aldo/keto reductase family | 5 | 127 | 1.6E-26 |
| 8 | g12734.t2 | ProSitePatterns | PS00062 | Aldo/keto reductase family signature 2. | 59 | 76 | - |
| 7 | g12734.t2 | SUPERFAMILY | SSF51430 | NAD(P)-linked oxidoreductase | 3 | 127 | 2.75E-41 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0047834 | D-threo-aldose 1-dehydrogenase activity | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
