General information for g12825.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Chitotriosidase-1.
Parent gene
- The parent gene g12825 is located on chr_1: 26444301..26445087 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12825 | g12825.t1 | isoform | g12825.t1 | 26439840 | 26444301 |
| chr_1 | g12825 | g12825.t1 | exon | g12825.t1.exon1 | 26439840 | 26439871 |
| chr_1 | g12825 | g12825.t1 | cds | g12825.t1.CDS1 | 26439840 | 26439871 |
| chr_1 | g12825 | g12825.t1 | exon | g12825.t1.exon2 | 26443078 | 26443132 |
| chr_1 | g12825 | g12825.t1 | cds | g12825.t1.CDS2 | 26443078 | 26443132 |
| chr_1 | g12825 | g12825.t1 | exon | g12825.t1.exon3 | 26443185 | 26443922 |
| chr_1 | g12825 | g12825.t1 | cds | g12825.t1.CDS3 | 26443185 | 26443922 |
| chr_1 | g12825 | g12825.t1 | exon | g12825.t1.exon4 | 26443982 | 26444120 |
| chr_1 | g12825 | g12825.t1 | cds | g12825.t1.CDS4 | 26443982 | 26444120 |
| chr_1 | g12825 | g12825.t1 | exon | g12825.t1.exon5 | 26444189 | 26444301 |
| chr_1 | g12825 | g12825.t1 | cds | g12825.t1.CDS5 | 26444189 | 26444301 |
| chr_1 | g12825 | g12825.t1 | TTS | g12825.t1 | 26445079 | 26445079 |
| chr_1 | g12825 | g12825.t1 | TSS | g12825.t1 | NA | NA |
Sequences
>g12825.t1 Gene=g12825 Length=1077
ATGTACCACATTCTGATATTACACCATAACCTTGTTTTGAATGTTTTAAATAAACATAAT
TTTGATGGGTTTGATTTTGATTGGGAGTATCCTGCACAAAGAGATACTACATATGGAAGT
GCTGATAAAGAAAATTTTGTGGAACTTTTAAAAGTACTTAAAAGTAAATTAAGCTCAAAT
GGAAAATTACTAACCATTGCAGTTGGAGCAACAGCTTCTTCTGCATCAGTTTCGTATGAC
ATTCCAAATGTTGCTGCAAATGTTGATTTTATCAATCTTATGTCATATGATCTGCATGGT
TTGTGGGATTCAAAAACTGGCATCAATTCGCCACTTTATTCGGGACCAAGTGATGTCAGT
TCATATGAAAAACAATTAAATGTAGACTCAATTGTTAATTATTGGTTAAATCAAGGATGT
CCAAAGAGTAAATTAATTGTCGGAATACCACTTTATGGACGAACTTTCACATTAGCAAAT
TCGAATAATAATGGTGTGGGTGCTCCTATATATGGTGGAGGAGAAATGGGTTCATTTGTT
CCAGAGTCTGGCTTTTTAGGATATAATGAGATATGCTACAATATAAATAATAAAGGTTGG
AGAAGATTTTGGGAAGACACACAAAAAGTTCCTTATGCAGTTAGTGGCAATCAATGGGTT
GGATATGATGATGCAGAATCATTATCTTATAAATTGAATTACATCAAAAACAGAGATTTA
GGTGGTGCCATGTTTTGGTCAATTGAGACTGATGATTTTGCAAATATTTGTGATAAAGGC
AAATTTCCTTTGATAAAAGCTGCTTTTAGTGCATTGATTAATAATTCGCCTGTTCCAATT
ACTACTGATAAACCAAATCCAACTGAAAATAATGGTGTGACAACCACTACAACAACAACT
CAAAAATCAAATAGTGGCTCAATTTGTTCAAATGGTGATGGCATATATCCAGATCCATTA
GATTGCAACAAATTTTATATATGTGCTGCTAATGTTCCGTACCATCAATCGTGTGGTGTT
GGCTTGAATTTTAATCCAAATGGATATTGTGACTGGCCTTATAATTTTTCATGCTAG
>g12825.t1 Gene=g12825 Length=358
MYHILILHHNLVLNVLNKHNFDGFDFDWEYPAQRDTTYGSADKENFVELLKVLKSKLSSN
GKLLTIAVGATASSASVSYDIPNVAANVDFINLMSYDLHGLWDSKTGINSPLYSGPSDVS
SYEKQLNVDSIVNYWLNQGCPKSKLIVGIPLYGRTFTLANSNNNGVGAPIYGGGEMGSFV
PESGFLGYNEICYNINNKGWRRFWEDTQKVPYAVSGNQWVGYDDAESLSYKLNYIKNRDL
GGAMFWSIETDDFANICDKGKFPLIKAAFSALINNSPVPITTDKPNPTENNGVTTTTTTT
QKSNSGSICSNGDGIYPDPLDCNKFYICAANVPYHQSCGVGLNFNPNGYCDWPYNFSC
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g12825.t1 | Gene3D | G3DSA:3.10.50.10 | - | 155 | 222 | 9.5E-27 |
| 11 | g12825.t1 | Gene3D | G3DSA:2.170.140.10 | Antimicrobial Protein | 299 | 358 | 2.1E-10 |
| 3 | g12825.t1 | PANTHER | PTHR11177 | CHITINASE | 12 | 300 | 1.4E-88 |
| 4 | g12825.t1 | PANTHER | PTHR11177:SF360 | CHITINASE 12-RELATED | 12 | 300 | 1.4E-88 |
| 2 | g12825.t1 | Pfam | PF00704 | Glycosyl hydrolases family 18 | 13 | 251 | 2.3E-65 |
| 1 | g12825.t1 | Pfam | PF01607 | Chitin binding Peritrophin-A domain | 309 | 358 | 1.4E-9 |
| 10 | g12825.t1 | ProSitePatterns | PS01095 | Chitinases family 18 active site. | 21 | 29 | - |
| 13 | g12825.t1 | ProSiteProfiles | PS50940 | Chitin-binding type-2 domain profile. | 306 | 358 | 13.0 |
| 8 | g12825.t1 | SMART | SM00636 | 2g34 | 2 | 251 | 1.2E-59 |
| 9 | g12825.t1 | SMART | SM00494 | chi_10 | 307 | 357 | 1.0E-8 |
| 7 | g12825.t1 | SUPERFAMILY | SSF51445 | (Trans)glycosidases | 12 | 272 | 1.05E-61 |
| 5 | g12825.t1 | SUPERFAMILY | SSF54556 | Chitinase insertion domain | 152 | 222 | 7.33E-23 |
| 6 | g12825.t1 | SUPERFAMILY | SSF57625 | Invertebrate chitin-binding proteins | 306 | 358 | 2.09E-12 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | MF |
| GO:0008061 | chitin binding | MF |
| GO:0005975 | carbohydrate metabolic process | BP |
| GO:0005576 | extracellular region | CC |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
