General information for g12901.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Kinesin-like protein Klp10A.
Parent gene
- The parent gene g12901 is located on chr_1: 26794146..26799311 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12901 | g12901.t1 | TSS | g12901.t1 | 26789483 | 26789483 |
| chr_1 | g12901 | g12901.t1 | isoform | g12901.t1 | 26789615 | 26799311 |
| chr_1 | g12901 | g12901.t1 | exon | g12901.t1.exon1 | 26789615 | 26789669 |
| chr_1 | g12901 | g12901.t1 | cds | g12901.t1.CDS1 | 26789615 | 26789669 |
| chr_1 | g12901 | g12901.t1 | exon | g12901.t1.exon2 | 26793954 | 26794156 |
| chr_1 | g12901 | g12901.t1 | cds | g12901.t1.CDS2 | 26793954 | 26794156 |
| chr_1 | g12901 | g12901.t1 | exon | g12901.t1.exon3 | 26794920 | 26795075 |
| chr_1 | g12901 | g12901.t1 | cds | g12901.t1.CDS3 | 26794920 | 26795075 |
| chr_1 | g12901 | g12901.t1 | exon | g12901.t1.exon4 | 26796026 | 26796092 |
| chr_1 | g12901 | g12901.t1 | cds | g12901.t1.CDS4 | 26796026 | 26796092 |
| chr_1 | g12901 | g12901.t1 | exon | g12901.t1.exon5 | 26797137 | 26797222 |
| chr_1 | g12901 | g12901.t1 | cds | g12901.t1.CDS5 | 26797137 | 26797222 |
| chr_1 | g12901 | g12901.t1 | exon | g12901.t1.exon6 | 26797292 | 26797524 |
| chr_1 | g12901 | g12901.t1 | cds | g12901.t1.CDS6 | 26797292 | 26797524 |
| chr_1 | g12901 | g12901.t1 | exon | g12901.t1.exon7 | 26797584 | 26797935 |
| chr_1 | g12901 | g12901.t1 | cds | g12901.t1.CDS7 | 26797584 | 26797935 |
| chr_1 | g12901 | g12901.t1 | exon | g12901.t1.exon8 | 26798006 | 26798836 |
| chr_1 | g12901 | g12901.t1 | cds | g12901.t1.CDS8 | 26798006 | 26798836 |
| chr_1 | g12901 | g12901.t1 | exon | g12901.t1.exon9 | 26798927 | 26799110 |
| chr_1 | g12901 | g12901.t1 | cds | g12901.t1.CDS9 | 26798927 | 26799110 |
| chr_1 | g12901 | g12901.t1 | exon | g12901.t1.exon10 | 26799172 | 26799311 |
| chr_1 | g12901 | g12901.t1 | cds | g12901.t1.CDS10 | 26799172 | 26799311 |
| chr_1 | g12901 | g12901.t1 | TTS | g12901.t1 | 26799965 | 26799965 |
Sequences
>g12901.t1 Gene=g12901 Length=2307
ATGGAGGGCTGTTCGATTGAAGTCGGAAACAGTGTAAACATTAAACGAAGTGATGGCCGT
GTACATTCAGCAATGGTATCAAAGCTGAATCAAGCTCAGCGTTCAGTGACTGTGGAATGG
TATGAACGAGGCGAGACCAAAGGCAAAGAGGTTGAACTAGATATACTACTGGTATTAAAT
CCTGAACTTATTCAAAATAAGCAGTCAACCATCATTCAACCTTCATCTCAAATACAAGCA
CCAATTAACTTGCAACGAGAATCATCTGATTCTTCAATTGACGATGATGCATACTTGGAT
GAGCAAGAAGATCCAATGACTGATCAACAGACACAAAATAACAATGAAACTTCAACAGTA
GCGACAAGTGGTAATACTCTGCCGATTAAAGCAACGGGAAATGCGGCGCGATCGAATCAA
ACACAAGGAAATATACAAAGATTAACGCGAGCCAATAATACTTCAAGTGCAGCTCTAAAT
GGAAATCGAATCTCAAAAATTGGAACATCTACAACTATTCACAACAATCAGGATCATTCC
GAAAACGTACCTCCACAGGCCAAGAAGGTTACAAATAATCGAATGTTAGTGACACAACAA
CAACAACAGACAAATCAACAACAGCAAGCAATGTCAAAAGCAGCAGCATCACGACGCTCA
TATGTAGTTAGTGAAGTTGAACGATTAAAAGAGAATCGTGAAAAAAGACGTGCTCGACAA
TTGGAAATGAAAGAGGAAAAGACAGCTTTAATGAATATGGATCCTGGTAATCCTAATTGG
GAGCTTGCTGCTATGATTAGGGAATATCAATCGACAATAGATTTTCGGCCCTTAATTGAT
GGTCTAGCAATAGAAGATCATCAAATTACTGTTTGTGTGAGAAAAAGACCATTGTCGAGA
AAAGAAATTATGAAAAAAGAGCTAGATGTGATTTCGGTTCCCTCAAAAGATACTTTGATT
GTACACGAACCAAAAACAAAAGTCGACCTTACAAAGTTCCTGGAGAATCACAATTTTCGA
TTCGATTATGCTTTCGATGATACCTGTAATAATGAGTTGGTTTATAAGTATACGGCTAAA
CCTCTCGTACAGACTATTTTTGAAGGTGGTATGGCTACATGCTTTGCCTATGGACAAACC
GGCTCAGGAAAAACGCATACAATGGGTGGAGATTTCAATGGCAAAGTACAAGATTGTAAG
ACGGGCATTTACGCTATGGCAGCAAAAGATGTTTTTATGTTCCTTCGAGGTCCAAAATAT
CGTCATTTGAATTTAACAATTTCGGCTTCATTTTTTGAGATTTACAGTGGCAAAGTTTTT
GATTTGTTATCTGAAAAGAATAAATTAAGAGTTTTAGAAGATGGTAAACAACAAGTTCAA
GTTGTGGGATTAACGGAACGTGTAGTAGATAATGTTGAGGAAGTATTAAAATTAATTCAA
CATGGAAATGTAACAAGAACGTCGGGTCAGACATCGGCGAATGCCAATTCATCACGCTCA
CATGCCGTCTTTCAGCTCGTCTTACGACCCGCAGGTTCGGCAAAAATACACGGAAAGTTT
TCTTTCATTGATTTGGCGGGCAATGAACGAGGCGCAGATACAAATTCAGCCAATCGTCAG
ACGCGAATGGAGGGAGCTGAAATCAACAAGTCATTGCTTGCGCTTAAAGAGTGTATTCGT
GCTTTAGGCAGGCAAAATGCTCATTTGCCATTCCGTGTAAGTAAATTAACTCAAGTTCTA
CGAGATTCCTTTATTGGAGAGAAAAGTAAAACATGTATGATAGCAATGATCAGTCCGGGA
CTGTCATCTTGTGAACACACTCTTAACACTTTACGATATGCAAATCGTGTTAAAGAATTA
GTAGCAATAGATCCATCTGAACGAAATGAAATGATCGATGATGAAGAACCAATGGACTCA
GAACCAAATGAGCAGAATGGAAATGGAAAGAAAATGGATCTGTCACAGTTGCGCTCACTT
AATCCTTTCCAAGAGCACGACATTAGTGTAGAATTGTATAATCAGCATGCTGCCATTTCG
GAGCTACAACAAGTTGAAGATGAAACGATTGATCAATTGAAATTACTCGCTGAATTTTAT
ACAAAATCCTTACCCGAATTAATGGAATTATGTAGAATGACAAATAACCCTGATTATGAT
CAGGATGCATTTTGTAAACGAGGAAACGAGCTTTTGCGACAGCTATTCTTTTATGCTCAG
CCGTGTGCAGATTTGTTAACCGATTTTCAATCAAAAATTGAAAAAGAAGAAATGATATCA
CATAAAATGATGCCTGGAAAACGCTAA
>g12901.t1 Gene=g12901 Length=768
MEGCSIEVGNSVNIKRSDGRVHSAMVSKLNQAQRSVTVEWYERGETKGKEVELDILLVLN
PELIQNKQSTIIQPSSQIQAPINLQRESSDSSIDDDAYLDEQEDPMTDQQTQNNNETSTV
ATSGNTLPIKATGNAARSNQTQGNIQRLTRANNTSSAALNGNRISKIGTSTTIHNNQDHS
ENVPPQAKKVTNNRMLVTQQQQQTNQQQQAMSKAAASRRSYVVSEVERLKENREKRRARQ
LEMKEEKTALMNMDPGNPNWELAAMIREYQSTIDFRPLIDGLAIEDHQITVCVRKRPLSR
KEIMKKELDVISVPSKDTLIVHEPKTKVDLTKFLENHNFRFDYAFDDTCNNELVYKYTAK
PLVQTIFEGGMATCFAYGQTGSGKTHTMGGDFNGKVQDCKTGIYAMAAKDVFMFLRGPKY
RHLNLTISASFFEIYSGKVFDLLSEKNKLRVLEDGKQQVQVVGLTERVVDNVEEVLKLIQ
HGNVTRTSGQTSANANSSRSHAVFQLVLRPAGSAKIHGKFSFIDLAGNERGADTNSANRQ
TRMEGAEINKSLLALKECIRALGRQNAHLPFRVSKLTQVLRDSFIGEKSKTCMIAMISPG
LSSCEHTLNTLRYANRVKELVAIDPSERNEMIDDEEPMDSEPNEQNGNGKKMDLSQLRSL
NPFQEHDISVELYNQHAAISELQQVEDETIDQLKLLAEFYTKSLPELMELCRMTNNPDYD
QDAFCKRGNELLRQLFFYAQPCADLLTDFQSKIEKEEMISHKMMPGKR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g12901.t1 | CDD | cd01367 | KISc_KIF2_like | 288 | 618 | 0.0 |
| 10 | g12901.t1 | Coils | Coil | Coil | 226 | 246 | - |
| 9 | g12901.t1 | Gene3D | G3DSA:3.40.850.10 | Kinesin | 258 | 623 | 1.9E-137 |
| 14 | g12901.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 104 | 124 | - |
| 15 | g12901.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 626 | 649 | - |
| 2 | g12901.t1 | PANTHER | PTHR47971:SF14 | KINESIN-LIKE PROTEIN | 23 | 763 | 2.1E-221 |
| 3 | g12901.t1 | PANTHER | PTHR47971 | KINESIN-RELATED PROTEIN 6 | 23 | 763 | 2.1E-221 |
| 5 | g12901.t1 | PRINTS | PR00380 | Kinesin heavy chain signature | 369 | 390 | 8.6E-29 |
| 6 | g12901.t1 | PRINTS | PR00380 | Kinesin heavy chain signature | 491 | 508 | 8.6E-29 |
| 4 | g12901.t1 | PRINTS | PR00380 | Kinesin heavy chain signature | 519 | 537 | 8.6E-29 |
| 7 | g12901.t1 | PRINTS | PR00380 | Kinesin heavy chain signature | 569 | 590 | 8.6E-29 |
| 1 | g12901.t1 | Pfam | PF00225 | Kinesin motor domain | 294 | 619 | 2.4E-94 |
| 13 | g12901.t1 | ProSitePatterns | PS00411 | Kinesin motor domain signature. | 518 | 529 | - |
| 16 | g12901.t1 | ProSiteProfiles | PS50067 | Kinesin motor domain profile. | 288 | 620 | 105.828 |
| 12 | g12901.t1 | SMART | SM00129 | kinesin_4 | 286 | 626 | 4.3E-133 |
| 8 | g12901.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 260 | 620 | 6.64E-114 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:1990939 | NA | NA |
| GO:0007018 | microtubule-based movement | BP |
| GO:0005524 | ATP binding | MF |
| GO:0003777 | microtubule motor activity | MF |
| GO:0008017 | microtubule binding | MF |
KEGG
Orthology
- This transcript has been annotated with K10393 (kinesin family member 2/24)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
