General information for g13020.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Arylsulfatase B.
Parent gene
- The parent gene g13020 is located on chr_1: 27552906..27558881 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13020 | g13020.t2 | TSS | g13020.t2 | 27550950 | 27550950 |
| chr_1 | g13020 | g13020.t2 | isoform | g13020.t2 | 27550974 | 27552119 |
| chr_1 | g13020 | g13020.t2 | exon | g13020.t2.exon1 | 27550974 | 27551205 |
| chr_1 | g13020 | g13020.t2 | cds | g13020.t2.CDS1 | 27550974 | 27551205 |
| chr_1 | g13020 | g13020.t2 | exon | g13020.t2.exon2 | 27551264 | 27551310 |
| chr_1 | g13020 | g13020.t2 | cds | g13020.t2.CDS2 | 27551264 | 27551310 |
| chr_1 | g13020 | g13020.t2 | exon | g13020.t2.exon3 | 27551560 | 27552119 |
| chr_1 | g13020 | g13020.t2 | cds | g13020.t2.CDS3 | 27551560 | 27552117 |
| chr_1 | g13020 | g13020.t2 | TTS | g13020.t2 | NA | NA |
Sequences
>g13020.t2 Gene=g13020 Length=839
ATGAAGACACAAATTTTAATCCTCATAATTGTAGTTCTCGAATTTTCTTCATCTTTACCA
CAAAATCAGAAGAAAAATGTTCTTATTATAGTAGCTGATGATCTTGGTTTCAATGATGTA
AGTTATCGTGGCAGTAATGAGATTCCAACTTATAATATCGATGCATTGGCATATGGTGGA
ATTGTTCTTGACCGATTTTATACTGCTCCAATGTGCACTCCATCACGAAGTGCATTGATG
ACTGGCAAATATCCTTTCCATACGGGAATGCAGAACTTTGTGATCGTATCAGATGAACCA
TGGGGACTTCCATTAAATGAAAAAGTAATGCCGCAATATTTCAAAGAAGCAGGATATTCA
ACACATCTTATCGGTAAATGGCACTTGGGATTATACAAAGAACCTTATACACCAATGCAA
CGTGGTTATGACACATTTTTTGGATATCATGGTCCTTACATTGGTTACTTTGATTACACT
CATAAAATGTTCACTCGAAATTATTCACGCGGCTACGATCTGCGTCGAAATGCAAATATA
GAATGGAGAAATGATCGAGTTTATGCTACAGACATGTTTACAAAAGAAGCAGTAGCTCTC
ATTGAGAATCTTAATAATAAAAATCCATTTTTCATGATGGTCAATCATTTGGCACCGCAT
GCTGGAAATGAAGATGTTCCATTGGAAGCTAAAGAAGAGGATATCAAGCAATTTAGTTAC
ATTAAGAATCCAAGGCGACAAATCTTGAGTGCGATGGTAAAATCATTGGATGACAGTGTT
GGTGAAATTGTTTTGAGTTTAAGAAGGAAAAATTTATTGGATGACACAATTATTATTTT
>g13020.t2 Gene=g13020 Length=279
MKTQILILIIVVLEFSSSLPQNQKKNVLIIVADDLGFNDVSYRGSNEIPTYNIDALAYGG
IVLDRFYTAPMCTPSRSALMTGKYPFHTGMQNFVIVSDEPWGLPLNEKVMPQYFKEAGYS
THLIGKWHLGLYKEPYTPMQRGYDTFFGYHGPYIGYFDYTHKMFTRNYSRGYDLRRNANI
EWRNDRVYATDMFTKEAVALIENLNNKNPFFMMVNHLAPHAGNEDVPLEAKEEDIKQFSY
IKNPRRQILSAMVKSLDDSVGEIVLSLRRKNLLDDTIII
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g13020.t2 | CDD | cd16029 | 4-S | 26 | 279 | 3.32558E-130 |
| 6 | g13020.t2 | Gene3D | G3DSA:3.40.720.10 | Alkaline Phosphatase | 22 | 279 | 7.1E-81 |
| 2 | g13020.t2 | PANTHER | PTHR10342 | ARYLSULFATASE | 7 | 279 | 2.5E-123 |
| 3 | g13020.t2 | PANTHER | PTHR10342:SF264 | MIP05773P | 7 | 279 | 2.5E-123 |
| 1 | g13020.t2 | Pfam | PF00884 | Sulfatase | 25 | 279 | 1.5E-45 |
| 8 | g13020.t2 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 18 | - |
| 9 | g13020.t2 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 4 | - |
| 10 | g13020.t2 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 5 | 13 | - |
| 11 | g13020.t2 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 14 | 18 | - |
| 7 | g13020.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 19 | 279 | - |
| 13 | g13020.t2 | ProSitePatterns | PS00523 | Sulfatases signature 1. | 70 | 82 | - |
| 14 | g13020.t2 | ProSitePatterns | PS00149 | Sulfatases signature 2. | 118 | 128 | - |
| 4 | g13020.t2 | SUPERFAMILY | SSF53649 | Alkaline phosphatase-like | 23 | 279 | 6.28E-75 |
| 5 | g13020.t2 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 20 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008484 | sulfuric ester hydrolase activity | MF |
| GO:0003824 | catalytic activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed