General information for g13022.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Arylsulfatase B.
Parent gene
- The parent gene g13022 is located on chr_1: 27560699..27561677 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g13022 | g13022.t1 | isoform | g13022.t1 | 27558327 | 27561677 |
| chr_1 | g13022 | g13022.t1 | exon | g13022.t1.exon1 | 27558327 | 27558354 |
| chr_1 | g13022 | g13022.t1 | cds | g13022.t1.CDS1 | 27558327 | 27558354 |
| chr_1 | g13022 | g13022.t1 | exon | g13022.t1.exon2 | 27559811 | 27559951 |
| chr_1 | g13022 | g13022.t1 | cds | g13022.t1.CDS2 | 27559811 | 27559951 |
| chr_1 | g13022 | g13022.t1 | exon | g13022.t1.exon3 | 27560010 | 27560056 |
| chr_1 | g13022 | g13022.t1 | cds | g13022.t1.CDS3 | 27560010 | 27560056 |
| chr_1 | g13022 | g13022.t1 | exon | g13022.t1.exon4 | 27560126 | 27560699 |
| chr_1 | g13022 | g13022.t1 | cds | g13022.t1.CDS4 | 27560126 | 27560699 |
| chr_1 | g13022 | g13022.t1 | exon | g13022.t1.exon5 | 27560847 | 27560902 |
| chr_1 | g13022 | g13022.t1 | cds | g13022.t1.CDS5 | 27560847 | 27560902 |
| chr_1 | g13022 | g13022.t1 | exon | g13022.t1.exon6 | 27560961 | 27561677 |
| chr_1 | g13022 | g13022.t1 | cds | g13022.t1.CDS6 | 27560961 | 27561677 |
| chr_1 | g13022 | g13022.t1 | TTS | g13022.t1 | 27561908 | 27561908 |
| chr_1 | g13022 | g13022.t1 | TSS | g13022.t1 | NA | NA |
Sequences
>g13022.t1 Gene=g13022 Length=1563
ATGAATTTAAAATTCCATATTGAAAAATTAGCTGATGATCTTGGTTTCAATGATGTAAGT
TATCGTGGCAGTAATGAGATTCCGACTTATAATATCGATGCATTGGCATATGGTGGAATT
GTTCTTGACCGATTTTATACTGCTCCAATGTGCACTCCATCACGAAGTGCATTGATGACT
GGCAAATATCCTTTTCATACGGGAATGCAGAACTTTATGATCTTATCAGATGAACCATGG
GGACTTCCATTAAATGAAAAAGTAATGCCGCAATATTTCAAAGAAGCAGGCTATTCAACA
CATCTTATCGGTAAATGGCACTTAGGATCGTTCAAAAAATCTTATACACCAATGCAACGT
GGTTATGACACATTTTTTGGATATCATGGTCCTTACATTGGTTACTTTGATTACACTCAT
AAAATGTTCACTCGAAATTATTCACGCGGTTACGATCTGCGTCGAAATGCAAATATAGAA
TGGAGAAATGATCGAGTTTATGCTACAGACATGTTTACAAAAGAAGCAGTAGCTGTCATT
GAGAATCTTAATAATAAAAATCCATTTTTCATGATGGTCAATCATTTGGCACCGCATGCT
GGAAATGAGGATGTTCCATTGGAAGCTAAAGAAGAAGATATCAGACAATTTAGTTACATT
AAGAATCCAAGGCGACAAATCTTGAGTGCGATGGTAAAATCCTTGGATGACAGTGTTGGT
GAAATTGTTTCAAGTCTAAGAAGGAAAAATGTATTGAAAGACACAATTATTATTTTCTAT
TCTGACAATGGTGGACCAACAGAATTTCTTCTTTCGACAACAGCATCAAATTATCCATTG
AAAGGTCAAAAACAATCCGCATGGGAAGGTGGTATAAGAACAGCAGCAATAATCTATGCA
CCATTTTTACCTCAGGGTGTCATAAGAAATCGCTATTTTTACATTGCTGACTTTCTTCCA
ACACTTTTAACAATTTCAAATGCGAATGTAAATATTAGTACACCAATTGATGGAATGGAT
TTGTCAAATATGCTTATGAATGATCGACCACCATATAGAGATGAAGTGTTGACAATTGAT
GATATTTTTGGGTATAGTTCATATATTCGAGGTGATTTCAAATTAGTCAATGGAAGTTCA
TCTGAAGATGGAATTGCAGATAAATGGCTTGGTTCTAACAACAACACAAATGTCAATGCA
GCAAAGTACCTTTCTAATGTTCTCAATTCGAAAGTCGCAATCTCTCTTCAGTTTCCACTA
ACGGAAAGAAAAATTTCGAGTTTACGTAAGAAAACGGTTGTCAAATGTGGTAACAATGTA
GCCAATAATTGTAACTTGCTGAAGGGTCCATGTCTGTTTAATATCATCAATGATCCGTGT
GAAAAAGTTAATTTGGCAACTACGCAGAAAGCTAAGATGACCTCAATGCTTTTAAGGTTT
AATCAAAAATTAAAAACAGTTGTTCCGGCATTGAGAAAACCACCAAATCCCAATTGCGAT
CCAATATTTTTCAATTTAACTTGGACTAATTGGGATGATTATCCACCTCATATAGTTATT
TGA
>g13022.t1 Gene=g13022 Length=520
MNLKFHIEKLADDLGFNDVSYRGSNEIPTYNIDALAYGGIVLDRFYTAPMCTPSRSALMT
GKYPFHTGMQNFMILSDEPWGLPLNEKVMPQYFKEAGYSTHLIGKWHLGSFKKSYTPMQR
GYDTFFGYHGPYIGYFDYTHKMFTRNYSRGYDLRRNANIEWRNDRVYATDMFTKEAVAVI
ENLNNKNPFFMMVNHLAPHAGNEDVPLEAKEEDIRQFSYIKNPRRQILSAMVKSLDDSVG
EIVSSLRRKNVLKDTIIIFYSDNGGPTEFLLSTTASNYPLKGQKQSAWEGGIRTAAIIYA
PFLPQGVIRNRYFYIADFLPTLLTISNANVNISTPIDGMDLSNMLMNDRPPYRDEVLTID
DIFGYSSYIRGDFKLVNGSSSEDGIADKWLGSNNNTNVNAAKYLSNVLNSKVAISLQFPL
TERKISSLRKKTVVKCGNNVANNCNLLKGPCLFNIINDPCEKVNLATTQKAKMTSMLLRF
NQKLKTVVPALRKPPNPNCDPIFFNLTWTNWDDYPPHIVI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g13022.t1 | CDD | cd16029 | 4-S | 10 | 378 | 5.33393E-171 |
| 7 | g13022.t1 | Gene3D | G3DSA:3.40.720.10 | Alkaline Phosphatase | 10 | 353 | 1.3E-122 |
| 8 | g13022.t1 | Gene3D | G3DSA:3.30.1120.10 | - | 354 | 481 | 1.3E-122 |
| 2 | g13022.t1 | PANTHER | PTHR10342 | ARYLSULFATASE | 10 | 515 | 3.4E-188 |
| 3 | g13022.t1 | PANTHER | PTHR10342:SF264 | MIP05773P | 10 | 515 | 3.4E-188 |
| 1 | g13022.t1 | Pfam | PF00884 | Sulfatase | 10 | 325 | 1.1E-55 |
| 5 | g13022.t1 | ProSitePatterns | PS00523 | Sulfatases signature 1. | 49 | 61 | - |
| 6 | g13022.t1 | ProSitePatterns | PS00149 | Sulfatases signature 2. | 97 | 107 | - |
| 4 | g13022.t1 | SUPERFAMILY | SSF53649 | Alkaline phosphatase-like | 10 | 511 | 1.02E-107 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008484 | sulfuric ester hydrolase activity | MF |
| GO:0003824 | catalytic activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed